Results 61 to 70 of about 479,217 (327)

Thermal Performance of an Energy Pile Group with a Deeply Penetrating U-Shaped Heat Exchanger

Energies, 2020
This study presents a novel heat exchanger configuration, called a deeply penetrating U-shaped configuration, for energy piles. The outlet water temperature, temperature variation along the tube, and heat transfer rate are simulated and computed using ...
Weidong Lyu, Hefu Pu, Jiannan (Nick) Chen   +2 more
doaj   +1 more source

X-ray Measurement of the subpixel structure of the XMM EPIC MOS CCD [PDF]

, 1999
We report here the results of a mesh experiment to measure the subpixel structure of the EPIC MOS CCDs on board the XMM X-ray observatory. The pixel size is 40$\mu$m square while the mesh hole spacing is 48$\mu$m, a combination quite different from our ...
Abbey, A. F., Bennie, P. J., Short, A. D., Tsunemi, H., Turner, M. J. L., Yoshita, K.   +5 more
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Study of CMS sensitivity to neutrinoless $\tau$ decay at LHC [PDF]

, 2002
The Large Hadron Collider (LHC), scheduled to start operation in 2006, is foreseen to provide in the first year of running a total of $\sim 10^{12}$ $\tau$ leptons.
Ellis, R. Santinelli
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Determination of the optimal row distance for double row piles and the calculation method for earth pressure between piles

Shuiwen dizhi gongcheng dizhi
The double-row pile system without a connecting beam is challenging to implement in practical engineering because of its complex load characteristics and the lack of a standardized model for soil pressure between piles.
Ke TANG, Hua ZHAO, Xuefeng TANG, Rusong CHENG   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Evaluation of compressive capacity of helical pile resting in cohesionless soil [PDF]

International Journal of Mining and Geo-Engineering
Current research deals with the numerical investigation on the behavior of helical piles resting in cohesionless soil subjected to compressive load.
Jitendra Yadav, Hitesh Rahi, Shaik Hussain   +2 more
doaj   +1 more source

3D Numerical Modeling of Large Piled-Raft Foundation on Clayey Soils for Different Loadings and Pile-Raft Configurations

Studia Geotechnica et Mechanica, 2020
In a piled-raft foundation, the interaction between structural elements and soil continuum can be simulated very precisely by numerical modeling. In the present study, 3D finite element model has been used to examine the settlement, load-sharing, bending
Mali Shivanand, Singh Baleshwar
doaj   +1 more source