Results 11 to 20 of about 39,152 (265)
The inhibitory effects of Npas4 on seizures in pilocarpine-induced epileptic rats. [PDF]
PLoS ONE, 2014 To explore the effects of neuronal Per-Arnt-Sim domain protein 4 (Npas4) on seizures in pilocarpine-induced epileptic rats, Npas4 expression was detected by double-label immunofluorescence, immunohistochemistry, and Western blotting in the brains of ...
Dan Wang +8 more
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Arquivos de Neuro-Psiquiatria, 2011 Pilocarpine-induced seizures can be mediated by increases in oxidative stress and by cerebral amino acid changes. The present research suggests that antioxidant compounds may afford some level of neuroprotection against the neurotoxicity of seizures in ...
P S Santos +5 more
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Structural determinants at the M2 muscarinic receptor modulate the RGS4-GIRK response to pilocarpine by impairment of the receptor voltage sensitivity. [PDF]
, 2017 Membrane potential controls the response of the M2 muscarinic receptor to its ligands. Membrane hyperpolarization increases response to the full agonist acetylcholine (ACh) while decreasing response to the partial agonist pilocarpine.
Chen, I-Shan +2 more
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Aging and topical pilocarpine concentrations effects on pupil size and tear flow rate
Journal of Optometry, 2010 Purpose: This is to evaluate the effects of age and different concentrations of pilocarpine on tear flow rate and pupil size. Methods: The tear flow rates and pupil sizes of eighty-one volunteers were measured with Schimer's strips and a meter rule gauge,
Michael O. Emina
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Ontogenic study of lithium-pilocarpine-induced status epilepticus in rats. [PDF]
, 1992 Lithium is known to potentiate the ability of pilocarpine to induce status epilepticus in rats. The goal of this study was to determine whether lithium could potentiate pilocarpine-induced seizures in developing animals.
Baram, TZ, Hirsch, E, Snead, OC
core +1 more source
Bioengineering & Translational Medicine, 2021 The sweat test is the gold standard for the diagnosis of cystic fibrosis (CF). The test utilizes iontophoresis to administer pilocarpine to the skin to induce sweating for measurement of chloride concentration in sweat.
Song Li +5 more
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Neurobiology of Disease, 2021 This study examines changes in synaptic transmission with progression of the chronic epileptic state. Male Sprague-Dawley rats (P40–45) were injected with either saline or pilocarpine.
Benjamin Owen +2 more
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PLoS ONE, 2019 Pilocarpine is an M3 muscarinic agonist that is widely used for the treatment of xerostomia caused by various diseases and medical conditions. Pilocarpine induced the secretion of salivary fluid in perfused submandibular glands of rats.
Takanori Narita +3 more
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Effect of pilocarpine mouthwash on salivary flow
Brazilian Journal of Medical and Biological Research, 2002 Pilocarpine is a cholinergic agonist that increases salivary flow and has been used to treat xerostomia. Oral intake is the most frequent route of administration.
R. Bernardi +7 more
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Liječnički vjesnik, 2023 Peptadecapeptide BPC -157 has been reported to have a large spectrum of in vivo activities, from anti-ulcer to central action on the brain dopaminergic system, in addition to the aforementioned, BPC-157 might counteract standard convulsant induced ...
Helen Marie Chiddenton +2 more
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