Results 31 to 40 of about 23,504 (181)
Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease
Arthritis &Rheumatology, EarlyView.Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel +12 more
wiley +1 more source
Status epilepticus in adults: From etiology to treatment response
Epilepsia, EarlyView.Abstract This study explored the association between etiology of status epilepticus (SE) and treatment responsiveness. Consecutive episodes of nonhypoxic SE in patients ≥14 years old were included. Etiology was classified into acute, remote, progressive, defined electroclinical syndromes, and unknown.
Simona Lattanzi +5 more
wiley +1 more source
Estudo farmacológico, fisiológico e comportamental de ratos tratados com dose subconvulsivante de pilocarpina [PDF]
, 2013 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013Este trabalho teve como objetivo ampliar e aprofundar o entendimento do modelo proposto de ...
Guarnieri, Leonardo de Oliveira
core
Pharmacokinetics of Pilocarpine
, 1995 An ion‐pair HPLC assay was established to measure pilocarpine in plasma and in urine. Half‐lives of 1 h and 30 min, respectively, were found for pilocarpine in blood and plasma after incubation at 37°C.
ROBERTS, M. S. +2 more
core +1 more source
Pharmaceuticals, 2022 Xerostomia is linked to an increased risk of dental caries, oral fungal infections, and speaking/swallowing difficulties, factors that may significantly degrade patients’ life, socially- or emotionally-wise.
Afroditi Kapourani +2 more
doaj +1 more source
Epilepsia, EarlyView.Abstract Theta oscillations (4–12 Hz) are a prominent network rhythm within hippocampal and parahippocampal structures. Driven by cholinergic and γ‐aminobutyric acidergic inputs originating from the medial septum, physiological theta gates network excitability to control spatial navigation, memory encoding, and sensorimotor integration during specific ...
Maxime Lévesque, Massimo Avoli
wiley +1 more source
Arthritis Research & Therapy, 2019 Background Primary Sjögren’s syndrome (pSS) is associated with dental caries. Pilocarpine, a salivary stimulant, can improve the amount and flow rate of saliva in patients with pSS.
Chung-Yuan Hsu +7 more
doaj +1 more source
Epilepsia Open, EarlyView.Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley +1 more source
Iraqi Journal of Pharmaceutical Sciences, 2017 Previous data indicated the effectiveness of silibinin as intraocular pressure (IOP) - lowering agent. The present study was performed to evaluate the interaction of silibinin with pilocarpine or cyclopentolate in lowering IOP in normotensive rabbits ...
Saad A. Hussain +3 more
doaj +3 more sources
Controlled delivery of pilocarpine.
, 1990 The purpose of this project was to fabricate biodegradable ophthalmic inserts for controlled delivery of pilocarpine and evaluate them by both in-vitro and in-vivo studies.
Nadkarni, Sreekant Raghuveer.
core +4 more sources