Results 11 to 20 of about 17,396 (187)

Don't Sweat It: Cannabinoid CB1 Receptors Reduce Sweating in a Mouse Model. [PDF]

open access: yesFASEB J
A new galvanic skin response‐based approach offers a simple method for measuring sweating in the paws of mice. This method is used to demonstrate that cannabinoid CB1 receptors reduce baseline sweating in mice, likely via inhibition of sympathetic acetylcholine release via axonal CB1 receptors.
Murataeva N   +3 more
europepmc   +2 more sources

Lipoic acid effects on glutamate and taurine concentrations in rat hippocampus after pilocarpine-induced seizures

open access: yesArquivos de Neuro-Psiquiatria, 2011
Pilocarpine-induced seizures can be mediated by increases in oxidative stress and by cerebral amino acid changes. The present research suggests that antioxidant compounds may afford some level of neuroprotection against the neurotoxicity of seizures in ...
P S Santos   +5 more
doaj   +1 more source

Aging and topical pilocarpine concentrations effects on pupil size and tear flow rate

open access: yesJournal of Optometry, 2010
Purpose: This is to evaluate the effects of age and different concentrations of pilocarpine on tear flow rate and pupil size. Methods: The tear flow rates and pupil sizes of eighty-one volunteers were measured with Schimer's strips and a meter rule gauge,
Michael O. Emina
doaj   +1 more source

Administration of pilocarpine by microneedle patch as a novel method for cystic fibrosis sweat testing

open access: yesBioengineering & Translational Medicine, 2021
The sweat test is the gold standard for the diagnosis of cystic fibrosis (CF). The test utilizes iontophoresis to administer pilocarpine to the skin to induce sweating for measurement of chloride concentration in sweat.
Song Li   +5 more
doaj   +1 more source

Pilocarpine [PDF]

open access: yesThe American Journal of the Medical Sciences, 1898
n ...
openaire   +2 more sources

Pilocarpine induces the residual secretion of salivary fluid in perfused submandibular glands of rats.

open access: yesPLoS ONE, 2019
Pilocarpine is an M3 muscarinic agonist that is widely used for the treatment of xerostomia caused by various diseases and medical conditions. Pilocarpine induced the secretion of salivary fluid in perfused submandibular glands of rats.
Takanori Narita   +3 more
doaj   +1 more source

Excitatory synaptic transmission in hippocampal area CA1 is enhanced then reduced as chronic epilepsy progresses

open access: yesNeurobiology of Disease, 2021
This study examines changes in synaptic transmission with progression of the chronic epileptic state. Male Sprague-Dawley rats (P40–45) were injected with either saline or pilocarpine.
Benjamin Owen   +2 more
doaj   +1 more source

Unraveling the Biosynthesis of Pilocarpine in

open access: yesNatural Product Communications, 2015
Pilocarpine is found exclusively in species of Pilocarpus and the presence of other imidazole alkaloids has been reported in several species of the genus. Pilocarpine has several important pharmaceutical applications. Although several imidazole alkaloids
Alexandra Christine Helena Frankland Sawaya   +2 more
doaj   +1 more source

Effect of pilocarpine mouthwash on salivary flow

open access: yesBrazilian Journal of Medical and Biological Research, 2002
Pilocarpine is a cholinergic agonist that increases salivary flow and has been used to treat xerostomia. Oral intake is the most frequent route of administration.
R. Bernardi   +7 more
doaj   +1 more source

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