Results 71 to 80 of about 39,152 (265)

Case report: Ten cases of acquired idiopathic generalized anhidrosis treated with oral pilocarpine

Journal of Cutaneous Immunology and Allergy
Acquired idiopathic generalized anhidrosis is a rare disease characterized by systemic anhidrosis or hypohidrosis without other systemic diseases. However, its etiology remains unclear.
Hanako Miyahara, Noriko Kubota, Mari Okune, Yoshiyuki Ishii, Naoko Okiyama, Toshifumi Nomura, Junichi Furuta   +6 more
doaj   +1 more source

Flight and Walking in Locusts–Cholinergic Co-Activation, Temporal Coupling and Its Modulation by Biogenic Amines [PDF]

, 2015
Walking and flying in locusts are exemplary rhythmical behaviors generated by central pattern generators (CPG) that are tuned in intact animals by phasic sensory inputs. Although these two behaviors are mutually exclusive and controlled by independent
Pflueger, Hans-Joachim, Rillich, Jan, Stevenson, Paul A.   +2 more
core   +1 more source

Effects of cell therapy on seizures in animal models of epilepsy: Systematic review and meta‐analysis

Epilepsia, EarlyView.
Abstract This study was undertaken to systematically evaluate the efficacy of cell therapy in reducing seizures in animal models of chronic epilepsy. Three databases, Ovid MEDLINE, Ovid Embase, and Web of Science, were searched using predetermined eligibility criteria.
Afaf S. Altalhi, Muhammad S. Javaid, Nigel C. Jones, Kim L. Powell, Patrick Kwan, Terence J. O'Brien, Ana Antonic‐Baker   +6 more
wiley   +1 more source

Neo-Timm staining in the thalamus of chronically epileptic rats [PDF]

, 2005
The thalamus is an important modulator of seizures and is severely affected in cholinergic models of epilepsy. In the present study, chronically epileptic rats had their brains processed for neo-Timm and acetylcholinesterase two months after the ...
Hamani, Clement, Mello, Luiz Eugenio Araujo de Moraes, Paulo, I. de   +2 more
core   +2 more sources

Extracellular vesicle microRNAs are biomarkers of focal epilepsy but not epilepsy‐related respiratory dysfunction

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the diagnostic value of a set of preselected candidate microRNAs (miRNAs) extracted from plasma‐based extracellular vesicles (EVs) to identify patients with seizure‐related respiratory dysfunction. Methods A two‐step design was applied.
Sylvain Rheims, Hayet Kouchi, Florence Busato, Stanislas Lagarde, David Derbala, Sébastien Boulogne, Mathilde Leclercq, Jessica Chenais, Sandrine Bouvard, Fabrice Bartolomei, Laurent Bezin, Jorg Tost   +11 more
wiley   +1 more source

In vitro effects of Pilocarpus microphyllus extracts and pilocarpine hydrochloride on Rhipicephalus (Boophilus) microplus

Revista Brasileira de Parasitologia Veterinária, 2016
The aim of this study was to assess the activity of aqueous (AE) and ethanolic extracts (EE) and pilocarpine hydrochloride, which were extracted and isolated from Pilocarpus microphyllus (Jaborandi), respectively, on Rhipicephalus (Boophilus) microplus ...
Karina Neoob de Carvalho Castro, David Fernandes Lima, Dolores Wolschick, Ivanilza Moreira de Andrade, Raimunda Cardoso dos Santos, Francisco José de Seixas dos Santos, Leiz Maria Costa Veras, Lívio Martins Costa-Júnior   +7 more
doaj   +1 more source

Cannabidiol reduces seizures and associated behavioral comorbidities in a range of animal seizure and epilepsy models [PDF]

, 2019
Objective Epilepsy is a progressive neurological disease characterized by recurrent seizures and behavioral comorbidities. We investigated the antiseizure effect of cannabidiol (CBD), in a battery of acute seizure models.
Barker-Haliski, Melissa, Bazelot, Michael, Glyn, Sarah, Jones, Nicholas, McNeish, Alister James, Patra, Pabitra H., Sandhu, Haramrit, Whalley, Benjamin J., White, H. Steve, Williams, Claire M.   +9 more
core   +4 more sources

Respiratory dysfunction and fatal apnea during pilocarpine‐induced status epilepticus

Epilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is second only to sudden unexpected death in epilepsy as a cause of seizure‐related mortality. The progression of respiratory dysfunction during experimental SE remains poorly characterized. We investigated how pilocarpine‐induced SE affects respiration in mice.
Chengsan Sun, Rachel Spera, John M. Williamson, Suchitra Joshi, Bhavya Guduru, Harini Ganabady, Jaideep Kapur   +6 more
wiley   +1 more source

Transdermal pilocarpine on the skin over salivary glands to increase salivation: an in vivo study

BMC Oral Health
Background Hyposalivation is treated using oral cholinergic drugs; however, systemic side effects occasionally lead to discontinuation of treatment.
Natsuko Ishida, Ayano Katsura, Koichi Takagaki, Hiroshi Arakawa, Tsutomu Shimada, Satoshi Mizuno, Yoshimichi Sai, Yukio Kato, Hiroyuki Nakamura, Yukio Suga, Ryo Matsushita   +10 more
doaj   +1 more source

The Evolving Role of Mesenchymal Stem Cells and Their Exosomes in Epilepsy Management: From Bench to Bedside [PDF]

Stem Cells Int
Epilepsy affects over 70 million individuals globally, with nearly one‐third of patients failing to achieve seizure control despite the continued availability of new technologies and medications. Current epilepsy research aims to prevent or arrest the onset and progression of epilepsy by seeking novel therapeutic targets and developing potent ...
Li A, Zhao Z, Mi R, Xue G.
europepmc   +2 more sources