Ecometabolomic Analysis of Wild Populations of Pilocarpus pennatifolius (Rutaceae) Using Unimodal Analyses [PDF]
Frontiers in Plant Science, 2019 Studies examining the diversity of plant specialized metabolites suggest that biotic and abiotic pressures greatly influence the qualitative and quantitative diversity found in a species. Large geographic distributions expose a species to a great variety
Paulo Mazzafera, Kevin Cj Nixon
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HPLC-ESI-MS/MS of Imidazole Alkaloids in Pilocarpus microphyllus [PDF]
Molecules, 2008 Pilocarpine, an important imidazole alkaloid, is extracted from the leaves of Pilocarpus microphyllus (Rutaceae), known in Brazil as jaborandi and used mainly for the treatment of glaucoma.
Alexandra Christine Helena Frankland Sawaya +2 more
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New chromosome numbers in Pilocarpus Vahl (Rutaceae) Novos números cromossômicos em Pilocarpus Vahl (Rutaceae) [PDF]
Acta Botânica Brasílica, 2000 Chromosome counts for eight species of Pilocarpus Vahl (Rutaceae) a native of Brazil are reported for the first time. Chromosome numbers were determined from mitotic root tip cells of seedlings derived from field collections and grown in the greenhouse ...
Ladislau A. Skorupa
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Unraveling the Biosynthesis of Pilocarpine in [PDF]
Natural Product Communications, 2015 Pilocarpine is found exclusively in species of Pilocarpus and the presence of other imidazole alkaloids has been reported in several species of the genus. Pilocarpine has several important pharmaceutical applications. Although several imidazole alkaloids
Alexandra Christine Helena Frankland Sawaya +2 more
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Potential Distribution of Pilocarpus microphyllus in the Amazonia/Cerrado Biomes under Near-Future Climate Change Scenarios [PDF]
Plants, 2023 Pilocarpus microphyllus Stapf. ex Wardlew. (Rutaceae) is an endemic and threatened medicinal plant species from tropical Brazil. Popularly known as “jaborandi”, it is the unique natural source of pilocarpine, an alkaloid used to medical treat glaucoma ...
Waléria P. Monteiro +4 more
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Decoding pilocarpine biosynthesis and its roles in Pilocarpus microphyllus through a comparative transcriptomics approach [PDF]
BMC Plant BiologyBackground Pilocarpus microphyllus, widely known as jaborandi, faces a decline in its natural population due to unsustainable harvesting for pilocarpine extraction, an imidazole alkaloid with significant pharmacological properties.
Mariane Brom Sobreiro +12 more
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Seasonal variation in the essential oil of Pilocarpus microphyllus Stapf. [PDF]
Anais da Academia Brasileira de Ciências, 2003 The essential oils of the leaves and fine stems of Pilocarpus microphyllus, collected on iron mineralized soil of the Serra de Carajás, Southeast of Pará State, Brazil, during the rainy and dry seasons, were obtained by hydrodistillation and analyzed by ...
FRANCISCA S. N. TAVEIRA +3 more
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Climate change and the sustainable use of medicinal plants: a call for “new” research strategies [PDF]
Frontiers in PharmacologyClimate change and human activities severely impact the viability of plants and ecosystems, threatening the environment, biodiversity, and the sustainable development of plant-based products.
Olha Mykhailenko +8 more
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ANATOMÍA FOLIAR DE PILOCARPUS GOUDOTIANUS TUL. (RUTACEAE)
Caldasia, 2002 El género Pilocarpus (Rutaceae), distribuido en la región neotropical, constituye unrecurso de gran importancia en el campo de la medicina, como materia prima para laobtención del nitrato de pilocarpina, el cual se utiliza en el tratamiento del glaucoma ...
HERMOSO GALLARDO LUIS +1 more
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Seasonal change in main alkaloids of jaborandi (Pilocarpus microphyllus Stapf ex Wardleworth), an economically important species from the Brazilian flora. [PDF]
PLoS ONE, 2017 Pilocarpus microphyllus Stapf ex Wardleworth (jaborandi, Rutaceae) is one of the most important Brazilian medicinal species owing to its content of pilocarpine (PIL), an alkaloid used for treating glaucoma and xerostomia.
David Fernandes Lima +13 more
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