Cytotoxic and Antileishmanial Potential of Pilocarpus microphyllus Essential Oil: In Vitro and In Silico Study [PDF]
Jaborandi (Pilocarpus microphyllus) essential oil is obtained by removal and characterization using GC‐MS, revealing γ‐cadinene and trans‐caryophyllene as major constituents. The oil exhibits biological activity, with antifungal action against Candida spp.
De Lima Sidney Gonçalo +2 more
exaly +3 more sources
Epiisopiloturine, an Alkaloid from Pilocarpus microphyllus, Attenuates LPS-Induced Neuroinflammation by Interfering in the TLR4/NF-κB-MAPK Signaling Pathway in Microglial Cells. [PDF]
Neuroinflammation is present in the pathophysiological mechanisms of several diseases that affect the central nervous system (CNS). Microglia have a prominent role in initiating and sustaining the inflammatory process. Epiisopiloturine (EPI) is an imidazole alkaloid obtained as a by‐product of pilocarpine extracted from Pilocarpus microphyllus ...
de Sousa JAC +7 more
europepmc +2 more sources
Herbal and Natural Treatments for the Management of the Glaucoma: An Update. [PDF]
Glaucoma causes the degeneration of the retinal ganglion cells (RGCs) and their axons, inducing a tissue reshaping that affects both the retina and the optic nerve head. Glaucoma care especially focuses on reducing intraocular pressure, a significant risk factor for progressive damage to the optic nerve.
Vitiello L +5 more
europepmc +2 more sources
A New Species of Pilocarpus Vahl (Rutaceae) from Peru
A new species of Pilocarpus Vahl (Ru- taceae) from Peru is described and illustrated as Pilocarpus manuensis Skorupa. The new taxon is known only from the type locality in Parque Na- cional Manu, Peru, and resembles Pilocarpus de- merarae Sandwith from Guyana.
exaly +4 more sources
Exploring the Therapeutic Potential of Traditional Antimalarial and Antidengue Plants: A Mechanistic Perspective. [PDF]
Malaria, a highly perilous infectious disease, impacted approximately 230 million individuals globally in 2019. Mosquitoes, vectors of over 10% of worldwide diseases, pose a significant public health menace. The pressing need for novel antimalarial drugs arises due to the imminent threat faced by nearly 40% of the global population and the escalating ...
Kamaraj C +12 more
europepmc +2 more sources
Hepatoprotective effects of Juglans regia on carbon tetrachloride-induced hepatotoxicity: In silico/in vivo approach. [PDF]
This study evaluated the liver‐protective effects of Juglans regia L. extract using a carbon tetrachloride (CCl4)‐induced hepatic damage rat model, demonstrating significant reductions in liver enzyme levels and bilirubin, along with histological evidence of liver injury mitigation.
Pandey B +3 more
europepmc +2 more sources
Linking seedling wood anatomical trade-offs with drought and seedling growth and survival in tropical dry forests. [PDF]
Summary Wood anatomy plays a key role in plants' ability to persist under drought and should therefore predict demography. Plants balance their resource allocation among wood cell types responsible for different functions. However, it remains unclear how these anatomical trade‐offs vary with water availability, and the extent to which they influence ...
González-Melo A +15 more
europepmc +2 more sources
Espécies de Pilocarpus Vahl (Rutaceae) da Amazônia brasileira [PDF]
Pilocarpus é gênero neotropical constituído de 16 espécies distribuídas desde o sul do México e América Central até o sul da América do Sul. O Brasil abriga 13 espécies, sendo que 11 delas ocorrem exclusivamente no território brasileiro.
Ladislau A. SKORUPA
doaj +1 more source
Unraveling the plant diversity of the Amazonian canga through DNA barcoding
Here we bring genetic information for the unique flora of the canga of the Serra dos Carajás in Eastern Amazon. DNA barcodes were obtained for 538 species, 323 genera, and 115 families of vascular plants, with 344 species being characterized for the first time.
Santelmo Vasconcelos +21 more
wiley +1 more source
Abstract Rutaceae is a family of angiosperms well known for the economically important genus Citrus. The division of Rutaceae into subfamilies is still inadequate and provisional. Previous phylogenetic studies at the family level are characterized by a limited sampling of genera and lack several crucial taxa. Here, we present a phylogenetic study based
Marc S. Appelhans +7 more
wiley +1 more source

