Results 11 to 20 of about 682 (124)

Seasonal change in main alkaloids of jaborandi (Pilocarpus microphyllus Stapf ex Wardleworth), an economically important species from the Brazilian flora. [PDF]

PLoS ONE, 2017
Pilocarpus microphyllus Stapf ex Wardleworth (jaborandi, Rutaceae) is one of the most important Brazilian medicinal species owing to its content of pilocarpine (PIL), an alkaloid used for treating glaucoma and xerostomia.
David Fernandes Lima, Luiza Ianny de Lima, Jefferson Almeida Rocha, Ivanilza Moreira de Andrade, Liliana Gonçalves Grazina, Caterina Villa, Liliana Meira, Leiz Maria Costa Véras, Iábita Fabiana Sousa Azevedo, Adriele Giaretta Biase, Joana Costa, Maria Beatriz P P Oliveira, Isabel Mafra, José Roberto de Souza de Almeida Leite   +13 more
doaj   +3 more sources

Industrial Scale Isolation, Structural and Spectroscopic Characterization of Epiisopiloturine from Pilocarpus microphyllus Stapf Leaves: A Promising Alkaloid against Schistosomiasis. [PDF]

PLoS ONE, 2013
This paper presents an industrial scale process for extraction, purification, and isolation of epiisopiloturine (EPI) (2(3H)-Furanone,dihydro-3-(hydroxyphenylmethyl)-4-[(1-methyl-1H-imidazol-4-yl)methyl]-, [3S-[3a(R*),4b]]), which is an alkaloid from ...
Leiz M C Véras, Vanessa R R Cunha, Filipe C D A Lima, Maria A Guimarães, Marianne M Vieira, Yuri D M Campelo, Vanessa Y Sakai, David F Lima, Paulo S Carvalho, Javier A Ellena, Paulo R P Silva, Luciene C Vasconcelos, Markus Godejohann, Helena M Petrilli, Vera R L Constantino, Yvonne P Mascarenhas, José Roberto de Souza de Almeida Leite   +16 more
doaj   +3 more sources

Extraction and Identification of Flavonoids from the Leaves of Pilocarpus microphyllus: Focus on Antioxidant Activity and Neuroprotective Profile

Drugs and Drug Candidates
This work is based on research aiming to extract and identify flavonoids from jaborandi (Pilocarpus microphyllus) leaves and investigate their antioxidant and acute antinociceptive capacity.
Márcia Luana Gomes Perfeito, Fábio de Oliveira Silva Ribeiro, Joilson Ramos de Jesus, Leiz Maria Costa Véras, Alyne Rodrigues de Araújo Nobre, Everton Moraes Lopes, José Carlos Eloi de Queiroz, Andreanne Gomes Vasconcelos, Miguel Gomes Cardoso, João Gonçalves, Fernanda Regina de Castro Almeida, Daniel Dias Rufino Arcanjo, José Roberto de Souza de Almeida Leite   +12 more
doaj   +3 more sources

Scientific and technological prospection of Pilocarpus microphyllus and epiisopilothurin related to their anti-inflammatory activity in wound treatment

International Journal of Advanced Engineering Research and Science, 2022
Wounds are a serious public health problem and tissue healing is a complex process that requires clinical intervention. Thus, the use of biomolecules, mainly extracted from plants, presents itself as an alternative that facilitates the innate mechanisms of tissue repair.
Daniel Vasconcelos
exaly   +3 more sources

Extrativismo, cultivo e privatização do jaborandi (Pilocarpus microphyllus Stapf ex Holm.; Rutaceae) no Maranhão, Brasil Extractivism, cultivation and privatization of jaborandi (Pilocarpus microphyllus Stapf ex Holm.; Rutaceae) in Maranhão, Brazil

Acta Botânica Brasílica, 2002
Um dos processos associados com a expansão de fronteiras em países em desenvolvimento consiste na privatização de recursos naturais, anteriormente de uso comum por populações tradicionais.
Claudio Urbano B. Pinheiro
doaj   +3 more sources

Alkaloids as Potential Phytochemicals against SARS-CoV-2: Approaches to the Associated Pivotal Mechanisms. [PDF]

Evid Based Complement Alternat Med, 2021
Since its inception, the coronavirus disease 2019 (COVID‐19) pandemic has infected millions of people around the world. Therefore, it is necessary to find effective treatments against Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2), as it is the viral source of COVID‐19.
Majnooni MB, Fakhri S, Bahrami G, Naseri M, Farzaei MH, Echeverría J.   +5 more
europepmc   +2 more sources

Hepatoprotective effects of Juglans regia on carbon tetrachloride-induced hepatotoxicity: In silico/in vivo approach. [PDF]

Food Sci Nutr
This study evaluated the liver‐protective effects of Juglans regia L. extract using a carbon tetrachloride (CCl4)‐induced hepatic damage rat model, demonstrating significant reductions in liver enzyme levels and bilirubin, along with histological evidence of liver injury mitigation.
Pandey B, Thapa S, Kaundinnyayana A, Panta S.   +3 more
europepmc   +2 more sources

An experimental study on the ocular effects of Pilocarpus microphyllus 5X on rabbit eye

International Journal of Homoeopathic Sciences
Kanchan Kumar, Subhajit Dey
exaly   +3 more sources

Climate change and the sustainable use of medicinal plants: a call for “new” research strategies [PDF]

Frontiers in Pharmacology
Climate change and human activities severely impact the viability of plants and ecosystems, threatening the environment, biodiversity, and the sustainable development of plant-based products.
Olha Mykhailenko, Olha Mykhailenko, Banaz Jalil, Lyndy J. McGaw, Javier Echeverría, Marce Takubessi, Marce Takubessi, Michael Heinrich, Michael Heinrich   +8 more
doaj   +2 more sources

In Vitro Schistosomicidal Activity of the Alkaloid-Rich Fraction from Ruta graveolens L. (Rutaceae) and Its Characterization by UPLC-QTOF-MS. [PDF]

Evid Based Complement Alternat Med, 2019
Schistosomiasis is a neglected tropical disease that affects million people worldwide, mostly in developing countries. Ruta graveolens (Rutaceae) is a plant used in folk medicine to treat several diseases, including parasitic infections. In this study, we reported the in vitro schistosomicidal activity of the R.
de Carvalho LSA, Queiroz LS, Alves Junior IJ, Almeida ADC, Coimbra ES, de Faria Pinto P, da Silva MPN, De Moraes J, Da Silva Filho AA.   +8 more
europepmc   +2 more sources