The Role of the Mammalian Prion Protein in the Control of Sleep [PDF]
Sleep disruption is a prevalent clinical feature in many neurodegenerative disorders, including human prion diseases where it can be the defining dysfunction, as in the case of the “eponymous” fatal familial insomnia, or an early-stage symptom as in ...
Amber Roguski, Andrew C. Gill
doaj +6 more sources
Diurnal rhythms of pinealocyte ultrastructure, pineal serotonin content and plasma melatonin level in the domestic pig. [PDF]
The study was conducted to investigate diurnal changes in pinealocyte ultrastructure, pineal serotonin content and plasma melatonin concentration in the domestic pig.
Marcin Nowicki+3 more
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Salt-inducible kinase 1 in the rat pinealocyte: adrenergic regulation and role in arylalkylamine N-acetyltransferase gene transcription. [PDF]
The recognition of the basic leucine zipper domain in the regulation of transcriptional activity of cAMP response element-binding protein by salt-inducible kinase (SIK) prompted our investigation of the regulatory role of this kinase in the induction of ...
R. Kanyo, D. Price, C. Chik, A. Ho
semanticscholar +2 more sources
Neural Adrenergic/Cyclic AMP Regulation of the Immunoglobulin E Receptor α-Subunit Expression in the Mammalian Pinealocyte [PDF]
The high affinity immunoglobulin E receptor (FcϵRI) complex is dedicated to immunoglobulin E-mediated allergic responses. Expression of the FcϵRI receptor is thought to be relatively stable and limited to mast cells, basophils, eosinophils, monocytes ...
Surajit Ganguly+9 more
semanticscholar +2 more sources
Ceramide inhibits the outward potassium current in rat pinealocytes [PDF]
In the present study, we investigated the effect of ceramide on the outward K+ current in rat pinealocytes using whole cell and single channel recordings. Three components of the whole cell outward K+ current were separated, an iberiotoxin (IBTX)‐sensitive K+ current (IKCa), a transient A current (IA) and a delayed rectifier current (IK).
B. Li+3 more
openaire +4 more sources
The pinealocytes--the main cellular elements of the pineal organ--are polarized, displaying a (photo)receptor and an axonic effector cell pole. The receptor endings are of two main types: they bear rod-type or cone-type outer segments characterized by ...
B. Vígh, I. Vígh‐Teichmann
semanticscholar +3 more sources
Adrenergic control of pinealocyte chondriome – an in vitro study [PDF]
Abstract Norepinephrine released from sympathetic innervation plays the main role in the regulation of melatonin secretion in mammalian pinealocytes. The present study was conducted for the following reasons: 1) to establish whether the pinealocyte chondriome is controlled by norepinephrine, 2) to determine the effect of adrenergic stimulation on ...
Bogdan Lewczuk+3 more
openaire +4 more sources
Connexin36 localization to pinealocytes in the pineal gland of mouse and rat. [PDF]
AbstractSeveral cell types in the pineal gland are known to establish intercellular gap junctions, but the connexin constituents of those junctions have not been fully characterized. Specifically, the expression of connexin36 (Cx36) protein andmRNAhas been examined in the pineal, but the identity of cells that produce Cx36 and that form Cx36‐containing
Wang SG+5 more
europepmc +4 more sources
Active zone proteins are dynamically associated with synaptic ribbons in rat pinealocytes [PDF]
Synaptic ribbons (SRs) are prominent organelles that are abundant in the ribbon synapses of sensory neurons where they represent a specialization of the cytomatrix at the active zone (CAZ).
Isabella Spiwoks‐Becker+8 more
openalex +5 more sources
Microglia in Circumventricular Organs: The Pineal Gland Example. [PDF]
The circumventricular organs (CVOs) are unique areas within the central nervous system. They serve as a portal for the rest of the body and, as such, lack a blood-brain barrier.
Muñoz EM.
europepmc +3 more sources