Forskolin stimulates pinealocyte cGMP accumulation Dramatic potentiation by an α1‐adrenergic → [Ca2+]i mechanism involving protein kinase C [PDF]
, 1989 A. Ho, C. Chik, D. C. Klein
semanticscholar +2 more sources
Modulation of Pineal Melatonin Synthesis by Glutamate Involves Paracrine Interactions between Pinealocytes and Astrocytes through NF-
, 2013 Darine Villela +10 more
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Molecular Basis for Defining the Pineal Gland and Pinealocytes as Targets for Tumor Necrosis Factor [PDF]
, 2011 The pineal gland, the gland that translates darkness into an endocrine signal by releasing melatonin at night, is now considered a key player in the mounting of an innate immune response.
Claudia E. Carvalho‐Sousa +7 more
openalex +5 more sources
Spatio-temporal dynamics of nuclear CREB1: what does it mean? [PDF]
, 2022 In the mammalian pineal gland (PG), cyclic AMP responsive element-binding protein 1 (CREB1) participates in the nocturnal melatonin synthesis that rhythmically modulates physiology and behavior.
Farías Altamirano, Luz Estefanía +5 more
core +1 more source
Study of the histomorphology of human pineal gland
National Journal of Clinical Anatomy, 2023 Introduction: Histologically, the pineal gland shows pinealocytes, glial cells, and sometimes calcific concretions. Age-related changes in these three components have been reported by various workers.
Gyanraj Singh +3 more
doaj +1 more source
Cellular Basis of Pineal Gland Development: Emerging Role of Microglia as Phenotype Regulator. [PDF]
PLoS One, 2016 The adult pineal gland is composed of pinealocytes, astrocytes, microglia, and other interstitial cells that have been described in detail. However, factors that contribute to pineal development have not been fully elucidated, nor have pineal cell ...
Ibañez Rodriguez MP +2 more
europepmc +7 more sources
CREB1 spatio-temporal dynamics within the rat pineal gland [PDF]
, 2023 In the rat pineal gland (PG), cyclic AMP responsive element-binding protein 1 (CREB1) participates in the nocturnal melatonin synthesis that rhythmically modulates physiology and behavior.
Farías Altamirano, Luz Estefanía +5 more
core +1 more source
On the presence of conspicuous electron dense bodies in the pinealocytes of the pig [PDF]
, 1979 The pinealocytes of the pig contain a large number of aldehydefuchsin positive granules. In order to determine their nature an ultrastructural study was carried out. Numerous bodies having a maximal diameter of about 1,600 nm were found.
César L. A. Gómez Dumm +1 more
openalex +3 more sources
Journal of Pineal Research, Volume 75, Issue 4, December 2023., 2023 Abstract Melatonin is synthesized in the pineal gland during nighttime in response to nocturnal increase in the activity of the enzyme aralkylamine N‐acetyltransferase (AANAT), the transcription of which is modulated by several homeodomain transcription factors. Recent work suggests that the homeodomain transcription factor ISL LIM homeobox 2 (ISL2) is
Kuno M.‐J. Mattern +6 more
wiley +1 more source
Autism Research, Volume 16, Issue 10, Page 1877-1890, October 2023., 2023 Abstract Prenatal exposure to valproic acid (VPA), a drug widely used to treat epilepsy and bipolar disorder, is an environmental risk factor for autism spectrum disorder (ASD). VPA has been used to reproduce the core symptoms of ASD in animal model organisms, including zebrafish.
Laura DeOliveira‐Mello +2 more
wiley +1 more source