Results 31 to 40 of about 2,857 (229)

Role and neural regulation of clock genes in the rat pineal gland: Clock modulates amplitude of rhythmic expression of Aanat encoding the melatonin‐producing enzyme

open access: yesJournal of Pineal Research, Volume 75, Issue 2, September 2023., 2023
Abstract Circadian clock gene expression in the suprachiasmatic nucleus (SCN) controls 24 h rhythms in body functions, but clock genes are also expressed in extra‐hypothalamic tissues, including the melatonin‐producing pineal gland. The nocturnal increase in pineal melatonin synthesis is a hallmark in circadian biology, but the role of local clock gene
Aurea S. Blancas‐Velazquez   +3 more
wiley   +1 more source

Distribution of the transcription factor islet‐1 in the central nervous system of nonteleost actinopterygian fish: Relationship with cholinergic and catecholaminergic systems

open access: yesJournal of Comparative Neurology, Volume 531, Issue 11, Page 1126-1146, August 2023., 2023
Abstract Islet‐1 (Isl1) is one of the most conserved transcription factors in the evolution of vertebrates, due to its continuing involvement in such important functions as the differentiation of motoneurons, among other essential roles in cell fate in the forebrain.
Daniel Lozano   +5 more
wiley   +1 more source

Epiphysis morphology under light and radiation exposure in experiment

open access: yesБюллетень сибирской медицины, 2003
Epiphysis is an organ of the control of biorhythms and adaptogenesis connected with photoperiodism. To evaluate photoradiomodificating effect and conarium plasticity using the methods of light and electron microscopy, there have been analyzed changes in ...
S. V. Logvinov   +2 more
doaj   +1 more source

The photoreceptor protective cGMP‐analog Rp‐8‐Br‐PET‐cGMPS interacts with cGMP‐interactors PKGI, PDE1, PDE6, and PKAI in the degenerating mouse retina

open access: yesJournal of Comparative Neurology, Volume 531, Issue 8, Page 935-951, June 2023., 2023
cGMP can bind 13 various interactors in the retina such as PKGI/II, PKAI/II, PDE1,2,3,5, and 6, as well as EPAC2. However, the promising neuroprotective Rp‐8‐Br‐PET‐cGMPS analog shows target specificity within the photoreceptors and only showed to bind seven known cGMP‐binding proteins, including PKGI, PDE1, PDE6, and PKAI.
Michel Rasmussen   +5 more
wiley   +1 more source

The melatonin contained in beer can provide health benefits, due to its antioxidant, anti‐inflammatory and immunomodulatory properties

open access: yesJournal of the Science of Food and Agriculture, Volume 103, Issue 8, Page 3738-3747, June 2023., 2023
Abstract Beer is a fermented beverage with a low alcohol content originating from cereal fermentation (barley or wheat). It forms part of the diet for many people. It contains melatonin (N‐acetyl‐5‐methoxytryptamine). Melatonin is a molecule with a wide range of antioxidant, oncostatic, immunomodulatory, and cytoprotective properties.
MDolores Maldonado   +2 more
wiley   +1 more source

Treatment of unexplained facial numbness with stellate ganglion blockade: A case report

open access: yesClinical Case Reports, Volume 11, Issue 1, January 2023., 2023
Abstract To date, there is no established treatment for facial numbness or dysesthesia of unspecified causes. Herein, we report a case of unexplained facial numbness and confirmed hypesthesia that achieved clinical response to stellate ganglion blockade (SGB).
Uno Imaizumi   +2 more
wiley   +1 more source

BMAL1 but not CLOCK is associated with monochromatic green light-induced circadian rhythm of melatonin in chick pinealocytes

open access: yesEndocrine Connections, 2019
The avian pineal gland, an independent circadian oscillator, receives external photic cues and translates them for the rhythmical synthesis of melatonin.
Shuhui Ma   +4 more
doaj   +1 more source

Insights about circadian clock in glioma: From molecular pathways to therapeutic drugs

open access: yesCNS Neuroscience &Therapeutics, Volume 28, Issue 12, Page 1930-1941, December 2022., 2022
We summarized the connection between cell cycle clock and circadian clock. Previous studies reported that circadian clock proteins can affect cyclin‐CDK complex expression through p21, c‐Myc, and Wee1, and then participate in the regulation of the cell cycle.
Zongqi Wang, Gang Chen
wiley   +1 more source

Protein and mRNA expression of gonadotropin-releasing hormone receptor in yaks during estrus

open access: yesRevista Brasileira de Zootecnia, 2018
To demonstrate the role of gonadotropin-releasing hormone (GnRH) in yaks (Bos grunniens), we characterized the expression of gonadotropin-releasing hormone receptor (GnRHR) mRNA and protein.
Sheng-dong Huo   +5 more
doaj   +1 more source

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