Results 41 to 50 of about 2,934 (238)

Histomorphology of Parenchymal Cells in the Prenatal Period of the Human Foetal Pineal Gland: An Observational Study

Journal of Medical Evidence
Background: Human foetal pineal gland, a cone-shaped structure located in the roof of mesencephalon, plays a pivotal role in regulating circadian rhythms and melatonin production.
Pooja Bhadoria, Urvi Sharma, Bhamini Sharma, Bhavya Mishra, Brijendra Singh   +4 more
doaj   +1 more source

Pinopsin Regulates Melatonin Production and Daily Locomotor Activity: Functional Insights From Gene‐Edited Xenopus Tadpoles

Journal of Pineal Research, Volume 78, Issue 2, March 2026.
ABSTRACT Circadian rhythm alignment depends on environmental light detection via opsins. Pinopsin, originally identified in the pineal organ of birds and later in amphibian pineal complex and eyes, may play a role in this process, though its function has not been genetically tested.
Neda Heshami, Ricardo D. Romero, Flavio S. J. de Souza, Gabriel E. Bertolesi, Sarah McFarlane   +4 more
wiley   +1 more source

Synaptic-like microvesicles, synaptic vesicle counterparts in endocrine cells, are involved in a novel regulatory mechanism for the synthesis and secretion of hormones [PDF]

, 2001
Microvesicles in endocrine cells are the morphological and functional equivalent of neuronal synaptic vesicles. Microvesicles accumulate various neurotransmitters through a transmitter-specific vesicular transporter energized by vacuolar H+-ATPase.
Hayashi, Mitsuko, Ishio, Shougo, Moriyama, Yoshinori, Yamada, Hiroshi, Yamamoto, Akitsugu, Yatsushiro, Shouki   +5 more
core  

The Effects of Food on Circadian Rhythm: A Comprehensive Review

eFood, Volume 6, Issue 5, October 2025.
(a) Light signals are received by the retina and transmitted to the suprachiasmatic nucleus (SCN), the master circadian clock, which synchronizes peripheral clocks in metabolic tissues via neural and humoral pathways (e.g., cortisol). (b) The molecular clock is governed by a transcriptional‐translational feedback loop.
Jiazheng Hu, Hongyu Ye, Mengxin Wang, Han Yang, Manxi Wu, Jinping Cao, Chongde Sun, Yue Wang   +7 more
wiley   +1 more source

Radioimmunoassay and immunocytochemical studies on the recovery of pineal innervation and function following unilateral denervation : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in physiology at Massey University [PDF]

, 1993
PLEASE NOTE Page 106 is missing from the original copyThe sympathetic noradrenergic neurons of the superior cervical ganglia provide the major source of innervation to the pineal gland Studies described in this thesis were designed to further ...
Prangley, John Richard
core  

Characterization of lymphocyte subsets over a 24-hour period in Pineal-Associated Lymphoid Tissue (PALT) in the chicken [PDF]

, 2006
BACKGROUND: Homeostatic trafficking of lymphocytes in the brain has important relevance to the understanding of CNS disease processes. The pineal gland of the chicken contains large accumulations of lymphocytes that suggest an important role related to ...
McNulty, John A, Mosenson, Jeffrey A
core   +3 more sources

Noradrenaline upregulates T‐type calcium channels in rat pinealocytes [PDF]

The Journal of Physiology, 2015
Key pointsThe mammalian pineal gland is a neuroendocrine organ that responds to circadian and seasonal rhythms. Its major function is to secrete melatonin as a hormonal night signal in response to nocturnal delivery of noradrenaline from sympathetic neurons.Culturing rat pinealocytes in noradrenaline for 24 h induced a low‐voltage activated transient ...
Haijie, Yu, Jong Bae, Seo, Seung-Ryoung, Jung, Duk-Su, Koh, Bertil, Hille   +4 more
openaire   +2 more sources

The Chronological Trigger: The Orchestra Between Homeobox Genes and the Circadian Clock During Development

Biology of the Cell, Volume 117, Issue 7, July 2025.
Homeobox genes associated with the circadian rhythm and the development of specific tissues, playing crucial roles in regulating cellular differentiation and the formation of structures during embryonic development. ABSTRACT As master regulators of embryonic development, regulating homeobox genes is fundamental for developmental biology.
Joice de Faria Poloni, Bruno César Feltes   +1 more
wiley   +1 more source

Luminal acidification of diverse organelles by V-ATPase in animal cells [PDF]

, 2000
Eukaryotic cells contain organelles bounded by a single membrane in the cytoplasm. These organelles have differentiated to carry out various functions in the pathways of endocytosis and exocytosis. Their lumina are acidic, with pH ranging from 4.5 to 6.5.
Futai, Masamitsu, Kanazawa, Hiroshi, Moriyama, Yoshinori, Oka, Toshihiko, Sun-Wada, Ge-hong, Wada, Yoh   +5 more
core  

The melatonergic system in mood and anxiety disorders and the role of agomelatine: implications for clinical practice [PDF]

, 2013
Melatonin exerts its actions through membrane MT1/MT2 melatonin receptors, which belong to the super family of G-protein-coupled receptors consisting of the typical seven transmembrane domains.
De Berardis D., di Giannantonio M., Fornaro Michele, Iasevoli Felice, Marini S., Martinotti G., Perna G., Quera-Salva M. A., Srinivasan V., Tomasetti C., Valchera A.   +10 more
core   +2 more sources