Results 41 to 50 of about 2,857 (229)
Czech Journal of Animal Science, 2014 Melatonin plays key roles in a wide range of mammalian body functions, which are mediated by the melatonin-specific cell surface receptor (MTNR1A and MTNR1B).
S.-D. Huo, R.-J. Long
doaj +1 more source
Expression and cellular localization of the transcription factor NeuroD1 in the developing and adult rat pineal gland [PDF]
, 2015 Circadian rhythms govern many aspects of mammalian physiology. The daily pattern of melatonin synthesis and secretion is one of the classic examples of circadian oscillations.
Benitez, Sergio G. +5 more
core +2 more sources
Sympathetic Innervation of the Mammalian Pineal Gland: Its Involvement in Ontogeny and Physiology, and in Pineal Dysfunction [PDF]
, 2023 In mammals, the melatonin-producing pineal gland (PG) receives sympathetic innervation from the superior cervical ganglia (SCG). This chapter describes the role of this innervation on the PG’s ontogeny and rhythmic function, along with consequences to ...
Amiotti, Juan B. +5 more
core +2 more sources
6-Sulfatoxymelatonin predicts treatment response to fluoxetine in major depressive disorder. [PDF]
Ther Adv Psychopharmacol, 2019 Background: To date, no biomarker has been able to predict antidepressant response at an early blockade of norepinephrine or serotonin uptake. The transient nocturnal increase in plasma melatonin levels is upregulated by blocking these uptakes.
Jury Freitas J +7 more
europepmc +3 more sources
Rheumatology &Autoimmunity, Volume 4, Issue 4, Page 218-225, December 2024.Mast cells (MCs) and MC‐derived tumor necrosis factor (TNF) are important in chronic inflammatory and autoimmune diseases and post‐viral syndromes, having important mechanisms of action, and therapeutic potential. MC and MC‐derived TNF activation are involved in conditions like COVID‐19, and neuroinflammation, linking TNF to various pathological ...
Rachel da Silveira Gorman +1 more
wiley +1 more source
Characterization of lymphocyte subsets over a 24-hour period in Pineal-Associated Lymphoid Tissue (PALT) in the chicken [PDF]
, 2006 BACKGROUND: Homeostatic trafficking of lymphocytes in the brain has important relevance to the understanding of CNS disease processes. The pineal gland of the chicken contains large accumulations of lymphocytes that suggest an important role related to ...
McNulty, John A, Mosenson, Jeffrey A
core +3 more sources
Cytopathology, Volume 35, Issue 5, Page 561-571, September 2024.Abstract Embryonal and pineal tumours represent a diverse group of central nervous system (CNS) neoplasms. While many of the small round blue cell tumours that make up the embryonal neoplasms share similar histologic qualities, there are several morphologic and cytologic characteristics that are useful in distinguishing different tumour types ...
Joseph Reznicek +4 more
wiley +1 more source
Synaptic-like microvesicles, synaptic vesicle counterparts in endocrine cells, are involved in a novel regulatory mechanism for the synthesis and secretion of hormones [PDF]
, 2001 Microvesicles in endocrine cells are the morphological and functional equivalent of neuronal synaptic vesicles. Microvesicles accumulate various neurotransmitters through a transmitter-specific vesicular transporter energized by vacuolar H+-ATPase.
Hayashi, Mitsuko +5 more
core
Mouse Models in Circadian Rhythm and Melatonin Research
Journal of Pineal Research, Volume 76, Issue 5, August 2024.ABSTRACT This contribution reviews the role of inbred and transgenic mouse strains for deciphering the mammalian melatoninergic and circadian system. It focusses on the pineal organ as melatonin factory and two major targets of the melatoninergic system, the suprachiasmatic nuclei (SCN) and the hypophysial pars tuberalis (PT).
Horst‐Werner Korf, Charlotte von Gall
wiley +1 more source
Melatonin and Seasonal Synchrony in Mammals
Journal of Pineal Research, Volume 76, Issue 5, August 2024.ABSTRACT In mammals, seasonal opportunities and challenges are anticipated through programmed changes in physiology and behavior. Appropriate anticipatory timing depends on synchronization to the external solar year, achieved through the use of day length (photoperiod) as a synchronizing signal.
David G. Hazlerigg +2 more
wiley +1 more source