Results 51 to 60 of about 2,934 (238)

Seizure‐related death exhibits a circadian rhythm independent of seizure timing or sleep in a mouse model of Dravet syndrome

The Journal of Physiology, Volume 603, Issue 12, Page 3571-3587, 15 June 2025.
Abstract figure legend Sudden unexpected death in epilepsy (SUDEP) frequently occurs at night when humans are asleep. Nocturnal mouse models of seizure‐associated death also exhibit higher mortality during the night. This nighttime risk of death may be under the regulation of independent circadian and sleep state‐dependent processes.
Benjamin L. Kreitlow, Ana T. Novella‐Maciel, Ariana M. Hernández Vázquez, Gordon F. Buchanan   +3 more
wiley   +1 more source

Expanding the scope of mast cell disease: Does mast cell‐derived TNF play a role in immune‐mediated chronic illness and autoimmunity?

Rheumatology &Autoimmunity, Volume 4, Issue 4, Page 218-225, December 2024.
Mast cells (MCs) and MC‐derived tumor necrosis factor (TNF) are important in chronic inflammatory and autoimmune diseases and post‐viral syndromes, having important mechanisms of action, and therapeutic potential. MC and MC‐derived TNF activation are involved in conditions like COVID‐19, and neuroinflammation, linking TNF to various pathological ...
Rachel da Silveira Gorman, Iffath Unissa Syed   +1 more
wiley   +1 more source

Embryonal and pineal tumours

Cytopathology, Volume 35, Issue 5, Page 561-571, September 2024.
Abstract Embryonal and pineal tumours represent a diverse group of central nervous system (CNS) neoplasms. While many of the small round blue cell tumours that make up the embryonal neoplasms share similar histologic qualities, there are several morphologic and cytologic characteristics that are useful in distinguishing different tumour types ...
Joseph Reznicek, Nima Sharifai, Pouya Jamshidi, Nitin Wadhwani, Jared T. Ahrendsen   +4 more
wiley   +1 more source

Mouse Models in Circadian Rhythm and Melatonin Research

Journal of Pineal Research, Volume 76, Issue 5, August 2024.
ABSTRACT This contribution reviews the role of inbred and transgenic mouse strains for deciphering the mammalian melatoninergic and circadian system. It focusses on the pineal organ as melatonin factory and two major targets of the melatoninergic system, the suprachiasmatic nuclei (SCN) and the hypophysial pars tuberalis (PT).
Horst‐Werner Korf, Charlotte von Gall
wiley   +1 more source

Melatonin and Seasonal Synchrony in Mammals

Journal of Pineal Research, Volume 76, Issue 5, August 2024.
ABSTRACT In mammals, seasonal opportunities and challenges are anticipated through programmed changes in physiology and behavior. Appropriate anticipatory timing depends on synchronization to the external solar year, achieved through the use of day length (photoperiod) as a synchronizing signal.
David G. Hazlerigg, Valérie Simonneaux, Hugues Dardente   +2 more
wiley   +1 more source

A Seasonal and Age-Related Study of Interstitial Cells in the Pineal Gland of Male Viscacha (Lagostomus maximus maximus) [PDF]

, 2017
The pineal gland of viscacha exhibits histophysiological variations throughout the year, with periods of maximal activity in winter and minimal activity in summer. The aim of this work is to analyze the interstitial cells (IC) in the pineal gland of male
Acosta, Acosta, Aguilera-Merlo, Aguilera-Merlo, Borregón, Boya, Böni, Calvo, Calvo, Calvo, Calvo, Calvo, Cernuda-Cernuda, Chaves, Cruceño, Dahl, Dominguez, Donato, Donato, Donato, Eng, Eng, Filippa, Filippa, Franco, Fuentes, Fuentes, Fuentes, Girod, Gonzales, Haimoto, Hernández Díaz, Huang, Inagaki, Ivaska, Jackson, Lehtonen, Liedtke, Llanos, Lopez-Egido, López-Muñoz, McCall, Muñoz, Muñoz, Muñoz, Muñoz, Møller, Nieminen, Oshima, Piezzi, Rambotti, Redford, Redondo, Redondo, Regodón, Rodriguez, Runembert, Safwat, Schachner, Schietke, Shibuki, Suzuki, Tolstonog, Tolstonog, Vollrath, Welsh, Yang   +66 more
core   +1 more source

The physiological and pathophysiological roles of copper in the nervous system

European Journal of Neuroscience, Volume 60, Issue 1, Page 3505-3543, July 2024.
Copper is absorbed in the small intestines via the copper transporter CTR1 and the divalent metal transporter DMT1 and is released into the circulation by the copper transporter ATP7A. Copper is then transported to the liver where it is stored and delivered by ATP7B to the copper binding protein ceruloplasmin.
Jenna Gale, Elias Aizenman
wiley   +1 more source

Melatonin uptake by cells: An answer to its relationship with glucose? [PDF]

, 2018
Melatonin, N-acetyl-5-methoxytryptamine, is an indole mainly synthesized from tryptophan in the pineal gland and secreted exclusively during the night in all the animals reported to date.
Aguado, Arturo, Cepas López, Vanesa, Cernuda Cernuda, Rafael, Hevia Sánchez, David, Mayo Barrallo, Juan Carlos, Quirós González, Isabel, Sainz Menéndez, Rosa María, Álvarez Artime, Alejandro   +7 more
core   +2 more sources

Microstructural aspect of pineal body: pinealocytes population

Intisari Sains Medis, 2018
Background: Pineal tissue was compound with 2 types of cell known as pinealocytes and astrocyte cell. Furthermore, microanatomical research of pineal body is a rare procedure conducted for several years even in Indonesia, and its anatomical aspect needs to be explained.  Aim: enrich the scope of knowledge related to mammalian pineal within the pineal
Gede Wirata, Putu Nia Calista Santoso, Putu Ayu Utami Dewantari   +2 more
openaire   +2 more sources

The Rohde‐like cells at the posterior end of the dorsal nerve cord of amphioxus (Cephalochordata)

Journal of Comparative Neurology, Volume 532, Issue 6, June 2024.
For adult amphioxus, we used serial block‐face scanning electron microscopy (SBSEM) to describe the three‐dimensional fine structure of enigmatic Rohde‐like cells (RLCs) at the extreme tail end of the dorsal nerve cord. Up to 40% of the cell surface was covered by microvilli (arrowheads) not detected previously, suggesting that these cells are ...
Nicholas D. Holland, Linda Z. Holland
wiley   +1 more source