The physiological and pathophysiological roles of copper in the nervous system
Copper is absorbed in the small intestines via the copper transporter CTR1 and the divalent metal transporter DMT1 and is released into the circulation by the copper transporter ATP7A. Copper is then transported to the liver where it is stored and delivered by ATP7B to the copper binding protein ceruloplasmin.
Jenna Gale, Elias Aizenman
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Radioimmunoassay and immunocytochemical studies on the recovery of pineal innervation and function following unilateral denervation : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in physiology at Massey University [PDF]
PLEASE NOTE Page 106 is missing from the original copyThe sympathetic noradrenergic neurons of the superior cervical ganglia provide the major source of innervation to the pineal gland Studies described in this thesis were designed to further ...
Prangley, John Richard
core
Circadian genomics of the chick pineal gland in vitro [PDF]
Background Chick pinealocytes exhibit all the characteristics of a complete circadian system, comprising photoreceptive inputs, molecular clockworks and an easily measured rhythmic output, melatonin biosynthesis. These properties make the in vitro pineal
Bailey, Michael J+5 more
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The Rohde‐like cells at the posterior end of the dorsal nerve cord of amphioxus (Cephalochordata)
For adult amphioxus, we used serial block‐face scanning electron microscopy (SBSEM) to describe the three‐dimensional fine structure of enigmatic Rohde‐like cells (RLCs) at the extreme tail end of the dorsal nerve cord. Up to 40% of the cell surface was covered by microvilli (arrowheads) not detected previously, suggesting that these cells are ...
Nicholas D. Holland, Linda Z. Holland
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Melatonin in energy control: Circadian time‐giver and homeostatic monitor
Abstract Melatonin is a neurohormone synthesized from dietary tryptophan in various organs, including the pineal gland and the retina. In the pineal gland, melatonin is produced at night under the control of the master clock located in the suprachiasmatic nuclei of the hypothalamus.
Etienne Challet, Paul Pévet
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A Seasonal and Age-Related Study of Interstitial Cells in the Pineal Gland of Male Viscacha (Lagostomus maximus maximus) [PDF]
The pineal gland of viscacha exhibits histophysiological variations throughout the year, with periods of maximal activity in winter and minimal activity in summer. The aim of this work is to analyze the interstitial cells (IC) in the pineal gland of male
Acosta+66 more
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Abstract Homeobox genes encode transcription factors that are widely known to control developmental processes. This is also the case in the pineal gland, a neuroendocrine brain structure devoted to nighttime synthesis of the hormone melatonin. Thus, in accordance with high prenatal gene expression, knockout studies have identified a specific set of ...
Martin F. Rath
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Inmunohistochemical methods showed that GABAergic cells, fibers, and terminals are widely distributed throughout the brain and spinal cord of the sturgeon. Comparison among sturgeon and other vertebrates, revealed numerous differences in the complexity of specific subsystems reflecting different trends followed by vertebrate brains during evolution ...
Ramón Anadón+2 more
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Nocturnal Light Pollution Synergistically Impairs Glucose Metabolism With Age and Weight in Monkeys
Over the past decades, the global prevalence of Type 2 diabetes mellitus (T2D) and impaired glucose tolerance (IGT) has been increasing at an epidemic rate, yet the exact cause remains unknown. It is widely accepted that glucose metabolism can be impaired by circadian rhythms and sleep disturbances.
Shuxing Wang+6 more
wiley +1 more source
Wpływ melatoniny, N-acetyloserotoniny i 6-hydroksymelatoniny na ultrastrukturę pinealocytów chomika syryjskiego (Mesocricetus auratus) [PDF]
Objectives: The aim of this study was to examine the effects of melatonin as well as of its precursor (N-acetylserotonin) and metabolite (6-hydroxymelatonin) on the ultrastructure of the pinealocytes of the Syrian hamster.
Karasek, Michał+3 more
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