The physiological and pathophysiological roles of copper in the nervous system
European Journal of Neuroscience, Volume 60, Issue 1, Page 3505-3543, July 2024.Copper is absorbed in the small intestines via the copper transporter CTR1 and the divalent metal transporter DMT1 and is released into the circulation by the copper transporter ATP7A. Copper is then transported to the liver where it is stored and delivered by ATP7B to the copper binding protein ceruloplasmin.
Jenna Gale, Elias Aizenman
wiley +1 more source
The Rohde‐like cells at the posterior end of the dorsal nerve cord of amphioxus (Cephalochordata)
Journal of Comparative Neurology, Volume 532, Issue 6, June 2024.For adult amphioxus, we used serial block‐face scanning electron microscopy (SBSEM) to describe the three‐dimensional fine structure of enigmatic Rohde‐like cells (RLCs) at the extreme tail end of the dorsal nerve cord. Up to 40% of the cell surface was covered by microvilli (arrowheads) not detected previously, suggesting that these cells are ...
Nicholas D. Holland, Linda Z. Holland
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Melatonin uptake by cells: An answer to its relationship with glucose? [PDF]
, 2018 Melatonin, N-acetyl-5-methoxytryptamine, is an indole mainly synthesized from tryptophan in the pineal gland and secreted exclusively during the night in all the animals reported to date.
Aguado, Arturo +7 more
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Melatonin in energy control: Circadian time‐giver and homeostatic monitor
Journal of Pineal Research, Volume 76, Issue 4, May 2024.Abstract Melatonin is a neurohormone synthesized from dietary tryptophan in various organs, including the pineal gland and the retina. In the pineal gland, melatonin is produced at night under the control of the master clock located in the suprachiasmatic nuclei of the hypothalamus.
Etienne Challet, Paul Pévet
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Noradrenaline upregulates T‐type calcium channels in rat pinealocytes [PDF]
The Journal of Physiology, 2015 Key pointsThe mammalian pineal gland is a neuroendocrine organ that responds to circadian and seasonal rhythms. Its major function is to secrete melatonin as a hormonal night signal in response to nocturnal delivery of noradrenaline from sympathetic neurons.Culturing rat pinealocytes in noradrenaline for 24 h induced a low‐voltage activated transient ...
Duk Su Koh +5 more
openaire +3 more sources
Histomorphometric examination of the pineal gland in foals and adult horses [PDF]
, 2018 WOS: 000425921400014This study was conducted to evaluate the pineal glands of the foal and adult horses with histomorphometry. The pineal glands were sectioned at a thickness of 40 mu m and stained with AgNOR for stereological analyses.
Bahar, Sadullah +3 more
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Rhythmic Diurnal Synthesis and Signaling of Retinoic Acid in the Rat Pineal Gland and Its Action to Rapidly Downregulate ERK Phosphorylation [PDF]
, 2018 Open access via Springer Compact Agreement Funding was provided by a Biological Sciences Research Council East of Scotland BioScience Doctoral Training Partnership PhD Studentship awarded to Anna Ashton.
Ashton, Anna +3 more
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Journal of Pineal Research, Volume 76, Issue 3, April 2024.Abstract Homeobox genes encode transcription factors that are widely known to control developmental processes. This is also the case in the pineal gland, a neuroendocrine brain structure devoted to nighttime synthesis of the hormone melatonin. Thus, in accordance with high prenatal gene expression, knockout studies have identified a specific set of ...
Martin F. Rath
wiley +1 more source
Morphological and molecular characterization of two trematode worms in the gastropod Asolene pulchella (Anton, 1859) [PDF]
, 2019 Asolene pulchella (Anton, 1859) Asolene pulchella (Caenogastropoda, Ampullariidae) is a native gastropod from La Plata River. In a previous study we reported the presence of parasite forms of Trematoda (Plathyhelminthes) in the digestive gland of adult ...
Dellagnola, F. A. +4 more
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Wpływ melatoniny, N-acetyloserotoniny i 6-hydroksymelatoniny na ultrastrukturę pinealocytów chomika syryjskiego (Mesocricetus auratus) [PDF]
, 2006 Objectives: The aim of this study was to examine the effects of melatonin as well as of its precursor (N-acetylserotonin) and metabolite (6-hydroxymelatonin) on the ultrastructure of the pinealocytes of the Syrian hamster.
Karasek, Michał +3 more
core +1 more source