Nocturnal Light Pollution Synergistically Impairs Glucose Metabolism With Age and Weight in Monkeys
Over the past decades, the global prevalence of Type 2 diabetes mellitus (T2D) and impaired glucose tolerance (IGT) has been increasing at an epidemic rate, yet the exact cause remains unknown. It is widely accepted that glucose metabolism can be impaired by circadian rhythms and sleep disturbances.
Shuxing Wang +6 more
wiley +1 more source
Chronic fluoxetine treatment increases daytime melatonin synthesis in the rodent [PDF]
Circadian rhythm disturbances can occur as part of the clinical symptoms of major depressive disorder and have been found to resolve with antidepressant therapy.
Licinio, Julio +3 more
core +2 more sources
Circadian genomics of the chick pineal gland in vitro [PDF]
Background Chick pinealocytes exhibit all the characteristics of a complete circadian system, comprising photoreceptive inputs, molecular clockworks and an easily measured rhythmic output, melatonin biosynthesis. These properties make the in vitro pineal
Bailey, Michael J +5 more
core +4 more sources
P76 | PERICAPILLARY SPACES IN THE SHEEP PINEAL GLAND – 2D AND 3D ANALYSIS
The structural organization of pericapillary spaces in the mammalian pineal gland varies significantly among species. In rats - the most widely used in pineal research - fenestrated capillaries are surrounded by wide pericapillary spaces rich in ...
doaj +1 more source
COSMOS 2044. Experiment K-7-19. Pineal physiology in microgravity: Relation to rat gonadal function [PDF]
It is now known that the pineal organ can interact with many endocrine and nonendocrine tissues in a regulatory fashion. Given its key role in the regulation of melatonin synthesis, its high concentration, and that its levels may persist longer than the ...
Asadi, H. +3 more
core +1 more source
THE ANATOMICAL RELATIONSHIPS, ULTRASTRUCTURE, AND FUNCTION OF THE PINEAL GLAND IN SOME COMMON LABORATORY RODENTS [PDF]
The pineal complex of rodents is made up of a pineal organ which developmentally always originates from the area between the habenular and posterior commissure and a pineal sac which is continuous with the choroid plexus of the third ventricle.
Gregorek, Joseph Chester
core +1 more source
Homeobox Genes and Melatonin Synthesis: Regulatory Roles of the Cone-Rod Homeobox Transcription Factor in the Rodent Pineal Gland [PDF]
Nocturnal synthesis of melatonin in the pineal gland is controlled by a circadian rhythm in arylalkylamine N-acetyltransferase (AANAT) enzyme activity. In the rodent, Aanat gene expression displays a marked circadian rhythm; release of norepinephrine in ...
Møller, Morten +2 more
core +2 more sources
Transplantation of the Mammalian Pineal Gland: Studies of Survival, Revascularization, Reinnervation and Recovery of Function [PDF]
The survival, revascularization, reinnervation, and recovery of function of transplanted newborn rat pineal glands were studied following grafting into four different locations in pinealectomized rats.
Wu, Wutian
core +1 more source
Cholinergic signal transduction cascades in rat pinealocytes: functional and ontogenetic aspects [PDF]
Christof Schomerus, Horst‐Werner Korf
openalex +1 more source
Adrenergic Regulation of the Distribution of Transducer of Regulated cAMP-Response Element-Binding Protein (TORC2) in Rat Pinealocytes [PDF]
Richard Kanyo +4 more
openalex +1 more source

