Results 31 to 40 of about 498,615 (306)
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
"My favorite time of day is … when I discuss new ideas and experimental results with my students. The most important lesson I have learnt … is to never give up and to maintain my enthusiasm for research." This and more about Huai-Ping Cong can be found on page 94.
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
gjacopo/PING: Pre-release of PING software
<p>This is a pre-release of PING software developed and deployed in data production environments.</p> <p>This software offers a collection of macro/function utilities implemented in R/SAS/Stata for statistical data handling and ...
Jacopo Grazzini +9 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Ping modo gráfico com Software PING TEST
Mostra uma ferramenta chamada Ping Test que dá um "Ping" através de uma interface gráficaEducação Profissional::Informação e ...
Ramos, Leandro
core +1 more source
A New Key Delivery Method in Wireless Network
The development of networking technologies and the increase of digital devices have made multimedia transmission quick and easy. However, digital data transmission over open communication channels has introduced a number of security implications, such as
Çağatay Ay
doaj
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Container Relocation and Retrieval Tradeoffs Minimizing Schedule Deviations and Relocations
Ports are striving to improve operational efficiency in the context of constantly growing volumes of trade. In this context, port terminal storage yard operation is key, since complexity and poor coordination lead to containers stacked without ...
Robert Klar +3 more
doaj +1 more source
With the development of the electric market, electric load forecasting has been increasingly pursued by many scholars. Because the electric load is affected by many factors, it is characterized by volatility and uncertainty, and it cannot be forecasted ...
Guo‐Feng Fan +4 more
doaj +1 more source

