Results 71 to 80 of about 543,490 (298)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Parametric Digital Twins for Preserving Historic Buildings: A Case Study at Löfstad Castle in Östergötland, Sweden

open access: yesIEEE Access
This study showcases the digitalization of Löstad Castle in Sweden to contribute to preserving its heritage values. The castle and its collections are deteriorating due to an inappropriate indoor climate.
Zhongjun Ni   +5 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Throughput and Delay Analysis of LWA With Bursty Traffic and Randomized Flow Splitting

open access: yesIEEE Access, 2019
We investigate the effect of bursty traffic in a long term evolution (LTE) and Wi-Fi aggregation (LWA)-enabled network. The LTE base station routes packets of the same IP flow through the LTE and Wi-Fi links independently.
Bolin Chen   +4 more
doaj   +1 more source

Ping modo gráfico com Software PING TEST

open access: yes, 2019
Mostra uma ferramenta chamada Ping Test que dá um "Ping" através de uma interface gráficaEducação Profissional::Informação e ...
Ramos, Leandro
core  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

A Multi-Heuristic Algorithm for Multi-Container 3-D Bin Packing Problem Optimization Using Real World Constraints

open access: yesIEEE Access
With the growing demand for sustainable and optimal packaging solutions, this study proposes a novel two-stage algorithm for the multi-container three-dimensional bin packing problem. The research addresses this problem within the context of a real-world
Anan Ashrabi Ananno, Luis Ribeiro
doaj   +1 more source

Application of the Weighted K-Nearest Neighbor Algorithm for Short-Term Load Forecasting

open access: yesEnergies, 2019
In this paper, the historical power load data from the National Electricity Market (Australia) is used to analyze the characteristics and regulations of electricity (the average value of every eight hours).
Guo-Feng Fan   +3 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

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