Results 101 to 110 of about 51,359 (234)

A novel detrimental homozygous mutation in the WFS1 gene in two sisters from nonconsanguineous parents with untreated diabetes insipidus [PDF]

, 2019
Given the limited lifespan and with the recent progress in experimental treatments for WS, timely diagnosis and multidisciplinary treatment for DI/DM, hydronephrosis, and visual/psychiatric status-maintaining quality of life-are of crucial ...
Delides, Alexandros, Dinopoulos, Argyrios, Kleanthous, Kleanthis, Manolakos, Emmanouil, Mastorakos, Georgios, Nikolopoulos, Thomas, Papadimitriou, Anastasios, Papadimitriou, Dimitrios T, Tiulpakov, Anatoly, Urano, Fumihiko, Voros, Gerasimos, Zoupanos, George   +11 more
core   +2 more sources

Rosiglitazone and Pioglitazone Alter Aromatase Kinetic Properties in Human Granulosa Cells

PPAR Research, 2011
We have previously reported that, in human granulosa cells, thiazolidinediones rosiglitazone and pioglitazone inhibit estrogen synthesis by interfering with androgen binding to aromatase, without an effect on aromatase mRNA or protein expression.
Takako Araki, Miroslava Varadinova, Michael Goldman, Zev Rosenwaks, Leonid Poretsky, Donna Seto-Young   +5 more
doaj   +1 more source

Cardiovascular Outcomes in Patients With Previous Myocardial Infarction and Mild Diabetes Mellitus Following Treatment With Pioglitazone

EClinicalMedicine, 2018
Background: Secondary prevention in patients with myocardial infarction (MI) is critically important to prevent ischaemic heart failure and reduce social burden. Pioglitazone improves vascular dysfunction and prevents coronary atherosclerosis, mainly via
Masanori Asakura, Jiyoong Kim, Hiroshi Asanuma, Yasuharu Nakama, Kengo Tsukahara, Yorihiko Higashino, Tetsuya Ishikawa, Shinji Koba, Mitsuru Tsujimoto, Hideo Himeno, Yasuyuki Maruyama, Takanori Ookusa, Shunichi Yoda, Hiroshi Suzuki, Shinji Okubo, Makoto Shimizu, Yuji Hashimoto, Kazuo Satake, Susumu Fujino, Hiroyasu Uzui, Yoshiyuki Nagai, Tohru Kohno, Sumio Mizuno, Makoto Nakahama, Hounin Kanaya, Toyoaki Murohara, Kazuki Fukui, Hiroyuki Takase, Nobuyuki Ohte, Takaaki Shiono, Masatake Fukunami, Tsutomu Endo, Reimin Sawada, Kenshi Fujii, Motoshi Takeuchi, Shuntaro Ikeda, Koichi Mizuno, Masaaki Uematsu, Taku Matsubara, Shoji Yano, Jun Takahashi, Kousei Ueda, Yoshihiko Kinoshita, Koichi Tamita, Hideki Hayashi, Toshimitsu Hamasaki, Masafumi Kitakaze   +46 more
doaj   +1 more source

Cost-effectiveness of pioglitazone in type 2 diabetes patients with a history of macrovascular disease: a German perspective

Cost Effectiveness and Resource Allocation, 2009
Background The aim of this study was to project health-economic outcomes relevant to the German setting for the addition of pioglitazone to existing treatment regimens in patients with type 2 diabetes, evidence of macrovascular disease and at high risk ...
Massi-Benedetti Massimo, Erny-Albrecht Katrina M, Goodall Gordon, Scherbaum Werner A, Erdmann Erland, Valentine William J   +5 more
doaj   +1 more source

Effects of vitamin D combined with pioglitazone hydrochloride on bone mineral density and bone metabolism in Type 2 diabetic nephropathy [PDF]

, 2017
Ling-Xu Wang, Na Wang, Xu Qingli, Wei Yan, Dong Li, Baolin Li   +5 more
openalex   +1 more source

Effects of Resveratrol on pharmacokinetics and pharmacodynamics of Pioglitazone in Diabetic rats [PDF]

Perspectives In Medical Research, 2017
Introduction: Diabetes is a group of metabolic disorders characterized by a chronic hyperglycaemic condition resulting from insufficient action of insulin.
Raju Devde1 , Narasimha Reddy Y2 , Sravanthi K3 , Abid Ali4 , Imran Khan5
doaj  

Redox-dependent gating of VDAC by mitoNEET. [PDF]

, 2019
MitoNEET is an outer mitochondrial membrane protein essential for sensing and regulation of iron and reactive oxygen species (ROS) homeostasis. It is a key player in multiple human maladies including diabetes, cancer, neurodegeneration, and Parkinson's ...
Bai, Fang, Jennings, Patricia A, Lipper, Colin H, Mittler, Ron, Nechushtai, Rachel, Onuchic, José N, Roy, Susmita, Sohn, Yang-Sung, Stofleth, Jason T   +8 more
core  

Pioglitazone Ameliorates Intracerebral Insulin Resistance and Tau-protein Hyperphosphorylation in Rats with Type 2 Diabetes [PDF]

, 2013
Shengqing Hu, Tao Jiang, Shuo Yang, Yan Yang   +3 more
openalex   +1 more source

Identification of Potential Therapeutic Targets in the Liver of Pioglitazone-Treated Type 2 Diabetes Sprague-Dawley Rats via Expression Profile Chip and iTRAQ Assay

Journal of Diabetes Research, 2018
The aim of the present study was to identify key antidiabetic nodes in the livers of pioglitazone-treated type 2 diabetes mellitus Sprague-Dawley rats by transcriptomic and proteomic analysis.
Zhong-Xia Lu, Wen-Jun Xu, Yang-Sheng Wu, Chang-Yu Li, Yi-Tao Chen   +4 more
doaj   +1 more source

Efficacy of pioglitazone in treatment of metabolic dysfunction-associated fatty liver disease

Al-Azhar Assiut Medical Journal
Background and aim Nonalcoholic fatty liver disease has emerged as a major public health challenge, with limited approved pharmacological therapies.
Mahmoud M. Khafagi, Hamdy M. Moustafa, Ahmed A. Ahmed, Mohamed A. Bashir, Abdelghany Aish, Amro M. Hassan   +5 more
doaj   +1 more source