Results 91 to 100 of about 23,850 (163)

Upcoming therapies for steatotic liver disease: Translating breakthroughs into clinical practice

Journal of Internal Medicine, Volume 300, Issue 4, Page 440-460, October 2026.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide and a leading cause of cirrhosis, hepatocellular carcinoma, and cardiometabolic morbidity. Often clinically silent until advanced fibrosis develops, management has largely relied on lifestyle interventions, with limited ...
Philip N. Newsome, Saima Ajaz
wiley   +1 more source

Recent Advances and Emerging Applications in Embryo Vitrification for Livestock

Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.
ABSTRACT Vitrification has progressively supplanted conventional slow freezing as the method of choice for embryo cryopreservation in both human medicine and animal production, particularly for in vitro‐produced embryos and for species or developmental stages highly sensitive to conventional freezing.
Cristina Cuello, Marcos Torregrosa‐Fuentes, Manuela Garcia‐Canovas, Adelina Lopez‐Jara, Inmaculada Parrilla, Maria A. Gil, Emilio A. Martinez   +6 more
wiley   +1 more source

Combination therapy with DPP-4 inhibitors and pioglitazone in type 2 diabetes: theoretical consideration and therapeutic potential

Vascular Health and Risk Management, 2008
Nasser MikhailEndocrinology Division, Olive View-UCLA Medical Center, David-Geffen School of Medicine, CA, USAAbstract: Sitagliptin and vildagliptin represent a new class of anti-diabetic agents that enhance the action of incretin hormones through ...
Nasser Mikhail
doaj  

Lichtgesteuerte Dosierung der PPARγ‐Aktivierung Mittels Schnell Relaxierender Photoschalter

Angewandte Chemie, Volume 138, Issue 40, 28 September 2026.
Um eine räumlich‐zeitliche Kontrolle der PPARγ‐Aktivität zu ermöglichen, entwickelten wir den schnell relaxierenden photoschaltbaren Agonisten 6, der PPARγ selektiv in seinem lichtinduzierten Z‐Zustand aktiviert und innerhalb von Sekunden (t1/2 = 47 s) in den inaktiven E‐Zustand relaxiert.
Loris Knümann, Alba Rodriguez‐Paniagua, Martin Reynders, Silke Duensing‐Kropp, Oliver Thorn‐Seshold, Vasily Morozov, Julian A. Marschner, Daniel Merk   +7 more
wiley   +1 more source

Modulation of TLR4 and upregulation of HO-1 & PPAR-γ by Pioglitazone ameliorates methotrexate-induced liver damage in rats

Future Journal of Pharmaceutical Sciences
Background Methotrexate is a frequently prescribed antifolate immunosuppressant and antineoplastic agent that has been associated with serious systemic adverse effects including hepatotoxicity.
Rasha Abdelhady, Rana M. Abdelnaby, Mohamed Elsayed Mohamed Amer, Nancy S. Younis, Ebtehal Mohammad Fikry   +4 more
doaj   +1 more source

Ectopic Adipocytes in Scarring Alopecias: Comparison With Normal Scalp and Potential Therapeutic Implications

Journal of Cutaneous Pathology, Volume 53, Issue 10, Page 878-882, October 2026.
Annelise de Almeida Verdolin, Nadia El Kadi, Leonard Sperling, Luciana Pantaleão, Maria Fernanda Reis Gavazzoni Dias   +4 more
wiley   +1 more source

Research progress on the pathophysiological mechanisms of pioglitazone-induced heart failure: a review. [PDF]

Front Cardiovasc Med
Li J, Zhang Y, Li X.
europepmc   +1 more source

Semaglutide and pioglitazone restore airway mucosal homeostasis by resolving <i>Pseudomonas aeruginosa</i> pyocyanin-induced mucus hypersecretion, ciliostasis, and type 2 airway inflammation. [PDF]

Front Immunol
Wu C, Kulkarni NA, Lew SQ, Choi W, Sivaguru M, Kosmider B, Nanjappa SG, Lau GW.   +7 more
europepmc   +1 more source

Cost-Effectiveness Analysis of Triple Oral Antidiabetic Drug Combination in Patients With Type 2 Diabetes Mellitus: An Outpatient Study in Indonesia. [PDF]

J ASEAN Fed Endocr Soc
Hanifiyah IA, Nita Y, Libriansyah, Ridwan A, Achmad GNV.   +4 more
europepmc   +1 more source

PPARγ-Dependent Pioglitazone Treatment Suppresses Neuroinflammation and Improves Cognition in Sepsis-Associated Encephalopathy in Mice. [PDF]

CNS Neurosci Ther
Zhang J, Wang P, Li N, Gao Y.
europepmc   +1 more source