Results 161 to 170 of about 3,933 (191)
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Journal of Pharmaceutical Investigation, 2016
The primary objective of the present investigation was to formulate and evaluate fixed dose bilayer tablet of two antihyperglycemic agents with different mechanisms of action to improve glycemic control in patients with type 2 diabetes. A secondary objective is to ensure that metformin release should be less in stomach and completely released in ...
Boddu Prasanthi +3 more
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The primary objective of the present investigation was to formulate and evaluate fixed dose bilayer tablet of two antihyperglycemic agents with different mechanisms of action to improve glycemic control in patients with type 2 diabetes. A secondary objective is to ensure that metformin release should be less in stomach and completely released in ...
Boddu Prasanthi +3 more
openaire +1 more source
Spectroscopic Study of Site-Selective Binding of Pioglitazone Hydrochloride to Trypsin
Journal of Applied Spectroscopy, 2019Site-selective binding between pioglitazone hydrochloride (PGH) and trypsin (TRP) was investigated by fluorescence spectroscopy, ultraviolet spectroscopy, synchronous fluorescence spectroscopy, and circular dichroism spectroscopy. The results demonstrated that PGH could quench the intrinsic fluorescence of TRP strongly by a static quenching process ...
Ch.-D. Wang +5 more
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Main Group Chemistry, 2018
A précised and reproducible HPLC method was developed for simultaneous estimation of antidiabetic drug, pioglitazone HCl and antihypertensive losartan potassium. Diabetics are prone to hypertension hence co-administration of antihypertensive and antidiabetic drugs is most common.
Ayad, Magda Mohamed +3 more
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A précised and reproducible HPLC method was developed for simultaneous estimation of antidiabetic drug, pioglitazone HCl and antihypertensive losartan potassium. Diabetics are prone to hypertension hence co-administration of antihypertensive and antidiabetic drugs is most common.
Ayad, Magda Mohamed +3 more
openaire +1 more source
DETERMINATION OF PIOGLITAZONE HYDROCHLORIDE IN BOTH PURE FORM AND PHARMACEUTICAL FORMULATIONS
2023A novel, high throughput and sensitive method is described for the determination of pioglitazone hydrochloride (PGZ-HCl) as anti-diabetic in its pure form and pharmaceutical formulations. The proposed method depends on the polarographic activity of in HCl (0.5 M) using by cyclic voltammetry (CV), and it showed well-defined one cathodic peak with high ...
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Yao xue xue bao = Acta pharmaceutica Sinica, 2008
To develop limited sampling strategy (LSS) for estimation of C(max) and AUC(0-t) and assessing the bioequivalence of two pioglitazone hydrochloride (PGT) preparations.Healthy subjects (n = 20), enrolled in a bioequivalence study, were received 30 mg PGT po of reference or test formulation. The plasma concentration of PGT was determined by the validated
Jun-jie, Ding +3 more
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To develop limited sampling strategy (LSS) for estimation of C(max) and AUC(0-t) and assessing the bioequivalence of two pioglitazone hydrochloride (PGT) preparations.Healthy subjects (n = 20), enrolled in a bioequivalence study, were received 30 mg PGT po of reference or test formulation. The plasma concentration of PGT was determined by the validated
Jun-jie, Ding +3 more
openaire +1 more source
Solid-State Screening and Evaluation of Pioglitazone Hydrochloride
Current Pharmaceutical Analysis, 2017B. Poornima +2 more
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UV Spectroscopic Degradation Study of Pioglitazone Hydrochloride
Asian Journal of Pharmaceutical Analysis, 2018Omkar A. Patil +5 more
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[Pharmacokinetic interaction of pioglitazone hydrochloride and atorvastatin calcium in Beagle dogs].
Yao xue xue bao = Acta pharmaceutica Sinica, 2016The object of this study is to investigate the pharmacokinetic interaction of pioglitazone hydrochloride and atorvastatin calcium in healthy adult Beagle dogs following single and multiple oral dose administration. A randomized, cross-over study was conducted with nine healthy adult Beagle dogs assigned to three groups.
He-Li, Chen +5 more
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