Results 21 to 30 of about 3,933 (191)

Method operable design region for robust RP-HPLC analysis of pioglitazone hydrochloride and teneligliptin hydrobromide hydrate: incorporating hybrid principles of white analytical chemistry and design of experiments

Future Journal of Pharmaceutical Sciences, 2023
Background A combination of pioglitazone hydrochloride with teneligliptin hydrobromide hydrate is used to treat type-2 diabetes. Several chromatographic techniques have been described in the literature for determination of each of these medications ...
Pintu Prajapati, Bageshree Rana, Veera Shakar Pulusu, Shailesh Shah   +3 more
doaj   +1 more source

A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]

, 2012
Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core   +2 more sources

Comparative effectiveness of dipeptidyl peptidase-4 (DPP-4) inhibitors and human glucagon-like peptide-1 (GLP-1) analogue as add-on therapies to sulphonylurea among diabetes patients in the Asia-Pacific region: a systematic review [PDF]

, 2014
The prevalence of diabetes mellitus is rising globally, and it induces a substantial public health burden to the healthcare systems. Its optimal control is one of the most significant challenges faced by physicians and policy-makers.
A Juutilainen, AA Riedel, AI Adler, AJ Garber, AR Saltiel, BD Green, BI Yan, BM Scirica, Brian C. Y. Fong, C Castell, C Levetan, Carmen K. M. Fan, CC Cowie, CE Van Dijk, CJ Bailey, CN Chan, Daisy D. X. Zhang, DC Simonson, DR Owens, DS Schade, FA Guisasola, François Blachier, Harry H. X. Wang, J Lopatynski, J Mest H, J Rosenstock, K Kaku, Kirin Q. L. Liu, L Groop, M Kobayashi, M Stumvoll, M Takihata, Mandy W. M. Kwan, Martin C. S. Wong, MC Wong, N Inagaki, N Inagaki, O Mosenzon, R Kawamori, RA DeFronzo, S Aronoff, S Clement, SE Kahn, SE Kahn, SE Nissen, Shannon T. S. Li, Sian M. Griffiths, Sky W. M. Chan, SL Zhang, T Kadowaki, V Mohan, W Gareth, W Yang, WB White, Y Guan, Y Seino, Y Seino, YG Kim, Z Zeng   +58 more
core   +3 more sources

Simultaneous Estimation of Metformin Hydrochloride, Pioglitazone Hydrochloride, and Glimepiride by RP-HPLC in Tablet Formulation [PDF]

Journal of Chromatographic Science, 2008
A simple, precise, rapid, and reproducible reversed-phase high-performance liquid chromatography method is developed for the simultaneous estimation of metformin hydrochloride (MET), pioglitazone hydrochloride (PIO), and glimepiride (GLP) present in multicomponent dosage forms. Chromatography is carried out isocratically at 25 degrees C +/- 0.5 degrees
Deepti, Jain, Surendra, Jain, Deepak, Jain, Maulik, Amin   +3 more
openaire   +2 more sources

Relaxation of human pulmonary arteries by PPARγ agonists [PDF]

, 2013
It has been suggested that activation of nuclear peroxisome proliferator-activated receptors γ (PPARγ) may represent a new strategy for the treatment of pulmonary arterial hypertension.
Barbara Malinowska, Eberhard Schlicker, Hanna Kozłowska, Marta Baranowska-Kuczko, Mirosław Kozłowski, Monika Kloza   +5 more
core   +1 more source

Development and validation of analytical procedure for analysis of polyvinylpyrrolidone in tablets containing metformin hydrochloride and pioglitazone hydrochloride [PDF]

Pharmacia
Polyvinylpyrrolidone (PVP) is a common excipient in pharmaceutical formulations due to its inert, biocompatible, and multifunctional properties. However, its presence can impact drug release.
Sri Paryanti, Benny Permana, Sophi Damayanti   +2 more
doaj   +3 more sources

Evaluation of Biochemical Toxicity and Antioxidant Properties of Pioglitazone on Albino Wistar Rats [PDF]

, 2016
Pioglitazone is one of the thiazolidinedione anti-diabetic drugs which have been used for the treatment of non-insulin dependent diabetes mellitus. This study aims at investigating the biochemical effects and safety of pioglitazone (PIO) at various ...
Ashano, Efejiro, Ogunlana, Olubanke Olujoke, Ogunlana, Oluseyi Ebenezer, Ugochukwu, Stanley K   +3 more
core   +1 more source

Pioglitazone and bladder cancer risk: a systematic review and meta-analysis [PDF]

, 2018
Current evidence about the association between pioglitazone and bladder cancer risk remains conflict. We aimed to assess the risk of bladder cancer associated with the use of pioglitazone and identify modifiers that affect the results.
Fu, Shuangshuang, Han, Jiali, Shi, Weilong, Song, Yiqing, Tang, Huilin, Wang, Tiansheng, Zhai, Suodi   +6 more
core   +1 more source

Estimation of Pioglitazone Hydrochloride and Metformin Hydrochloride in Tablets by Derivative Spectrophotometry and Liquid Chromatographic Methods [PDF]

Journal of AOAC INTERNATIONAL, 2005
Abstract Two simple and accurate methods of analysis to determine pioglitazone hydrochloride (PIO) and metformin hydrochloride (MET) in combined dosage forms were developed using second-derivative spectrophotometry and reversed-phase liquid chromatography (LC).
Madhira B, Shankar, Vaibhav D, Modi, Dimal A, Shah, Kashyap K, Bhatt, Rajendra S, Mehta, Madhira, Geetha, Binita J, Patel   +6 more
openaire   +2 more sources

Simultaneous Estimation of Glimepiride, Rosiglitazone and Pioglitazone Hydrochloride in the Pharmaceutical Dosage Form

E-Journal of Chemistry, 2010
A simple, specific, accurate and economical gradient reversed phase liquid chromatographic (RP-HPLC) method was developed and subsequently validated for the determination of glimipiride, rosiglitazone and pioglitazone hydrochloride.
Freddy H. Havaldar, Dharmendra L. Vairal
doaj   +1 more source