Results 41 to 50 of about 1,633 (196)

Pressurized intraperitoneal aerosol chemotherapy, reasons for interrupting treatment: a systematic review of the literature

Pleura and Peritoneum, 2023
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) gives encouraging results in the treatment of peritoneal metastasis (PM). The current recommendations require at least 3 sessions of PIPAC. However, some patients do not complete the full treatment
Ezanno Anne-Cecile, Malgras Brice, Pocard Marc   +2 more
doaj   +1 more source

Impact of Pressurized Intraperitoneal Aerosol Chemotherapy on Quality of Life and Symptoms in Patients with Peritoneal Carcinomatosis: A Retrospective Cohort Study

Gastroenterology Research and Practice, 2017
Background. Peritoneal cancer treatment aims to prolong survival, but preserving Quality of Life (QoL) under treatment is also a priority. Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) is a novel minimally invasive repeatable treatment ...
Hugo Teixeira Farinha, Fabian Grass, Amaniel Kefleyesus, Chahin Achtari, Benoit Romain, Michael Montemurro, Nicolas Demartines, Martin Hübner   +7 more
doaj   +1 more source

Advancements in nebulizers for pressurized intraperitoneal aerosol chemotherapy (PIPAC). [PDF]

Pleura Peritoneum
Abstract Introduction Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is an innovative intraperitoneal drug delivery technique utilizing a nebulizer to aerosolize liquid chemotherapy agents under pressure, distributing them evenly throughout the peritoneal cavity to achieve therapeutic
Lin X, Yang Z, Li Y.
europepmc   +3 more sources

Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma

International Journal of Cancer, Volume 147, Issue 10, Page 2847-2861, 15 November 2020., 2020
Abstract Pancreatic ductal adenocarcinoma (PDAC) is resistant to virtually all chemo‐ and targeted therapeutic approaches. Epigenetic regulators represent a novel class of drug targets. Among them, BET and HDAC proteins are central regulators of chromatin structure and transcription, and preclinical evidence suggests effectiveness of combined BET and ...
Xin Zhang, Tim Zegar, Tim Weiser, Feda H. Hamdan, Benedict‐Tilman Berger, Romain Lucas, Dimitrios‐IIias Balourdas, Swetlana Ladigan, Phyllis F. Cheung, Sven‐Thorsten Liffers, Marija Trajkovic‐Arsic, Bjoern Scheffler, Andreas C. Joerger, Stephan A. Hahn, Steven A. Johnsen, Stefan Knapp, Jens T. Siveke   +16 more
wiley   +1 more source

Pressurized Intra Peritoneal Aerosol Chemotherapy in patients suffering from peritoneal carcinomatosis of pancreatic adenocarcinoma. [PDF]

PLoS ONE, 2017
Patients suffering from peritoneal carcinomatosis of pancreatic adenocarcinoma were treated with Pressurized Intra Peritoneal Aerosol Chemotherapy (PIPAC), initial clinical findings are presented.Single institution, tertiary referral center certified for
Tanja Khosrawipour, Veria Khosrawipour, Urs Giger-Pabst   +2 more
doaj   +1 more source

Safe management of surgical smoke in the age of COVID‐19

BJS (British Journal of Surgery), Volume 107, Issue 11, Page 1406-1413, October 2020., 2020
The COVID‐19 pandemic is unprecedented and raises concerns regarding transmission of the virus within surgical smoke. This review summarizes the current evidence and provides advice for its management. Bad for your health? Background The COVID‐19 global pandemic has resulted in a plethora of guidance and opinion from surgical societies. A controversial
N. G. Mowbray, J. Ansell, J. Horwood, J. Cornish, P. Rizkallah, A. Parker, P. Wall, A. Spinelli, J. Torkington   +8 more
wiley   +1 more source

The scientific report from the first pressurized intraperitoneal aerosol chemotherapy (PIPAC) procedures performed in the eastern part of Central Europe

Journal of International Medical Research, 2018
Objective To perform a single-centre, detailed analysis of the preparations for the introduction of the first pressurized intraperitoneal aerosol chemotherapy (PIPAC) programme in the eastern part of Central Europe.
Maciej Nowacki, Wojciech Zegarski
doaj   +1 more source

The Negative Impact of a Non‐Therapeutic Laparotomy in Patients With Inoperable Colorectal Peritoneal Metastases

Journal of Surgical Oncology, Volume 133, Issue 7, Page 843-851, June 2026.
ABSTRACT Background The peritoneum is the third most prevalent location for metastases of colorectal cancer. In patients with resectable disease, cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CRS‐HIPEC) is the preferred treatment in the Netherlands, achieving median overall survival (OS) of 36–42 months. However, during
Teun van den Heuvel, Lars van Kesteren, Simon Nienhuijs, Pim Burger, Tineke Buffart, Jurriaan Tuynman, Ignace De Hingh   +6 more
wiley   +1 more source

Clinical characteristics, treatment response, and survival outcomes in melanoma patients with cavity carcinomatosis: A retrospective analysis

International Journal of Cancer, Volume 158, Issue 9, Page 2418-2428, 1 May 2026.
What's new? Cavity carcinomatosis, a late manifestation of cancer, fuels tumor formation throughout a large area, most commonly the peritoneal and pleural cavities. The condition also can lead to resistance to otherwise effective treatment strategies.
Zhongqiao Lin, Li Zhu, Yuyang Huang, Lizhu Chen, Yuping Lu, Yu Chen, Jing Lin   +6 more
wiley   +1 more source

Response Evaluation in Patients with Peritoneal Metastasis Treated with Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) [PDF]

, 2023
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) directed therapy emerged as a treatment of peritoneal metastasis (PM) a decade ago. The response assessment of PIPAC is not uniform.
Signe Roensholdt, Roensholdt, Signe; id_orcid, Martin Graversen, Graversen, Martin, Mortensen, Michael Bau; id_orcid, Sönke Detlefsen, Michael Mortensen, Detlefsen, Sönke; id_orcid, Michael Bau Mortensen, Detlefsen, Sönke, Mortensen, Michael Bau, Roensholdt, Signe   +11 more
core   +1 more source