Results 41 to 50 of about 3,380 (162)

Metabolome and Mycobiome of Aegilops tauschii Subspecies Differing in Susceptibility to Brown Rust and Powdery Mildew Are Diverse

Plants
The present study demonstrated the differences in the seed metabolome and mycobiome of two Aegilops tauschii Coss accessions with different resistance to brown rust and powdery mildew.
Veronika N. Pishchik, Elena P. Chizhevskaya, Arina A. Kichko, Tatiana S. Aksenova, Evgeny E. Andronov, Vladimir K. Chebotar, Polina S. Filippova, Tatiana V. Shelenga, Maria H. Belousova, Nadezhda N. Chikida   +9 more
doaj   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

Dengue Virus Molecular Targets and Antiviral Drug Development: Advances, Challenges and Therapeutic Perspectives

ChemistrySelect, Volume 11, Issue 33, 1 September 2026.
This narrative review analyzes DENV molecular targets, including structural proteins (C, prM/M, E), non‐structural components (NS1NS5), and host factors, alongside small‐molecule candidates in preclinical and clinical phases. Owing to high structural conservation, the NS2B‐NS3 protease and NS5 (RdRp/MTase) remain primary drug discovery focuses, while ...
Aryane Lucia da Silva Aguiar De Oliveira, José Arion Da Silva Moura, Pedro César de Souza, Marcelo Arthur Dias da Costa Santana, Matheus Vinicius Guimarães de Melo, Douglas Carvalho Francisco Viana, Marina Galdino Da Rocha Pitta, Isabella Luiza Ralph de Oliveira, Maira Galdino Da Rocha Pitta   +8 more
wiley   +1 more source

LURP1, a SARD1‐regulated protein, coordinates with the helper NLR ADR1 to promote plant immunity

New Phytologist, Volume 251, Issue 5, Page 2852-2866, September 2026.
The working model of LURP1 function in plant immunity. Upon pathogen infection, SARD1/CBP60g promotes the transcription of LURP1 directly. LURP1 likely functions as an adaptor protein that associates with the PRRs–BAK1 complexes at the plasma membrane (PM) while also interacts with the ADR1 family helper NLRs.
Xueru Liu, Weijie Huang, Zhengxi Gong, Chenying Li, Siyu Chen, Shucai Wang, Yuelin Zhang, Xin Li   +7 more
wiley   +1 more source

Systemic acquired resistance: an emerging role for jasmonates in local signal biogenesis, translocation and distal signal decoding

New Phytologist, Volume 251, Issue 6, Page 3142-3158, September 2026.
Jasmonate signalling underpins establishment of plant systemic acquired resistance (SAR). Activation of the hypersensitive response (HR) not only contains the pathogen but establishes broad spectrum resistance in unchallenged leaves. The strong burst of reactive oxygen/nitrogen species initiating the HR results in lipid peroxidation (illustrated by ...
Fay Bennett, Erin Stroud, Pradeep Kachroo, Murray Grant   +3 more
wiley   +1 more source

Stability issue of amino acids and organic acids in exhaled breath condensate and the potential use for lung cancer diagnosis

Journal of Chromatography Open
As a non-invasive biofluid, exhaled breath condensate (EBC), which contains various volatile and non-volatile metabolites, such as amino acids (AAs) and organic acids (OAs), offers immense potential for metabolic monitoring and disease diagnosis ...
Korcan Korba, Ebru Calkan Yildirim, Su Ozgur, Tuncay Goksel, Fatma Nil Ertas, Levent Pelit   +5 more
doaj   +1 more source

Sinapoylglucose: malate sinapoyltransferase SNG1 negatively regulates drought resistance by crosstalk with abscisic acid signaling in Arabidopsis

The Plant Journal, Volume 127, Issue 5, September 2026.
SUMMARY Drought stress has a profound impact on yield, with massive repercussions for agricultural production. In addition to ABA, the central hormone controlling the plant response to drought, secondary metabolites also play important functions in drought stress; however, the precise nature of their roles is still obscure. Metabolomics analysis of ABA‐
Kun Li, Jiangtao Jia, Yong Yang, Minghui Zhang, Shulin Zhang, Xiaohan Liang, Zhiwen Lu, Min Xu, Zhe Wang, Fengbo Yang, Haipeng Li, Jinggong Guo, Kun‐peng Jia, Lam‐Son Phan Tran, Jose R. Botella, Weiqiang Li, Yuchen Miao   +16 more
wiley   +1 more source

A plant‐centric view of class B flavin‐dependent monooxygenase evolution and diversity

The Plant Journal, Volume 127, Issue 5, September 2026.
SUMMARY Flavin‐dependent monooxygenases (FMOs) are ancient enzymes present throughout all kingdoms of life. FMOs utilize flavin‐based cofactors to incorporate an oxygen atom into their substrate, altering its chemical properties. Class B FMOs are enriched throughout the plant kingdom, catalyzing essential reactions for plant development and defense ...
Joachim Møller Christensen, Elizabeth H. J. Neilson   +1 more
wiley   +1 more source

SARD1 and CBP60g redundantly regulate N‐hydroxypipecolic acid‐ and salicylic acid‐dependent systemic immunity but are dispensable for the activation of indolic defense metabolism

The Plant Journal, Volume 127, Issue 6, September 2026.
SUMMARY We investigated the roles of the cognate, redundantly acting transcription factors SARD1 and CPB60g in the metabolic reprogramming of leaves of Arabidopsis thaliana suffering from bacterial infection or UV light exposure. Comprehensive metabolite analyses reveal that SARD1/CBP60g exert distinct influences on major stress‐inducible metabolic ...
Mona Perrar, Marlene Gross, Patrick Petzsch, Karl Köhrer, Jürgen Zeier   +4 more
wiley   +1 more source

Chemical Composition, Nutritional Profile, and Bioactive Properties of Diplotaxis tenuifolia, a Health-Promoting Food

Molecules
Diplotaxis tenuifolia (Brassicaceae), valued for its culinary use and bioactive potential, has not yet been comprehensively characterized in terms of its chemical composition and biological properties.
Sandrine Ressurreição, Lígia Salgueiro, Artur Figueirinha   +2 more
doaj   +1 more source