Results 71 to 80 of about 14,807 (258)

High performance computing of explicit schemes for electrofusion jointing process based on message-passing paradigm [PDF]

open access: yes, 2005
The research focused on heterogeneous cluster workstations comprising of a number of CPUs in single and shared architecture platform. The problem statements under consideration involved one dimensional parabolic equations.
Alias, Norma   +2 more
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

The Connection between Star-Forming Galaxies, AGN Host Galaxies and Early-Type Galaxies in the SDSS

open access: yes, 2007
We present a study of the connection between star-forming galaxies, AGN host galaxies, and normal early-type galaxies in the Sloan Digital Sky Survey (SDSS).
Busarello G.   +9 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

First measurement of Mg isotope abundances at high redshifts and accurate estimate of Delta alpha/alpha

open access: yes, 2011
(Abridged) We use a high-resolution spectrum of the quasar HE0001-2340 observed with the UVES/VLT to measure Mg isotope abundances in the intervening absorption-line systems at high redshifts.
Aldenius   +49 more
core   +1 more source

Real-Time analysis and visualization for single-molecule based super-resolution microscopy [PDF]

open access: yes, 2013
Accurate multidimensional localization of isolated fluorescent emitters is a time consuming process in single-molecule based super-resolution microscopy.
Choquet, Daniel   +4 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

ENERGETICALLY OPTIMAL WORK OF WATER INTAKE STRUCTURES FROM UNDERGROUND SOURCES

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2019
Objectives Perfecting of the existing schemes of water delivery in the pure tank on a pressure piping and increase in efficiency of submersible pumps on water intaking constructions from underground sources.
I. Yu. Purusova
doaj   +1 more source

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