Results 81 to 90 of about 77,758 (248)

Long-Term Stability Comparison between an Original and a Generic Version of Piperacillin/Tazobactam in Dextrose 5 % Infusion Polyolefin Bags at 5 ± 3 °C after Microwave Freeze-Thaw Treatment

Pharmaceutical Technology in Hospital Pharmacy, 2018
Piperacillin-Tazobactam is frequently infused in hospitals. The use of a generic version was considered after the out of stock of the brand name Tazocin®.
Huvelle Sophie, Godet Marie, Galanti Laurence, Closset Mélanie, Bihin Benoît, Jamart Jacques, Hecq Jean-Daniel   +6 more
doaj   +1 more source

Piperacillin enhances the inhibitory effect of tazobactam on β-lactamase through inhibition of organic anion transporter 1/3 in rats

Asian Journal of Pharmaceutical Sciences, 2019
To assess the mechanism of the pharmacokinetic interaction between piperacillin and tazobactam, renal excretion and pharmacokinetic studies of piperacillin/tazobactam were investigated in normal and bacteremia rats.
Shilei Yang, Zhihao Liu, Changyuan Wang, Shijie Wen, Qiang Meng, Xiaokui Huo, Huijun Sun, Xiaodong Ma, Jinyong Peng, Zhonggui He, Kexin Liu   +10 more
doaj   +1 more source

The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]

, 2017
Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K, Diaz, Jose J, Jr, Huston, Jared M, May, Addison K, Mazuski, John E, Mollen, Kevin P, Nadler, Evan P, O\u27Neill, Patrick J, Prince, Jose M, Rosengart, Matthew R, Sawyer, Robert G, Tessier, Jeffrey M   +11 more
core   +3 more sources

Perspectives of Healthcare Professionals, Patients and Family Members on Managing Regular Medications Across the Perioperative Pathway: An Exploratory Qualitative Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore healthcare professionals', patients', and family members' experiences of managing regular medications across the perioperative pathway in a specialist cancer hospital in Melbourne. Design An exploratory qualitative study using a descriptive‐interpretive approach.
Atefeh Mehrabifar, Elizabeth Manias, Thomas E. Poulton, Bernhard Riedel, Janelle Penno, Patricia Nicholson   +5 more
wiley   +1 more source

Research Progress on Risk Factors for Acute Kidney Injury After Antibiotic‐Loaded Bone Cement Spacer Treatment for Periprosthetic Joint Infection

Orthopaedic Surgery, EarlyView.
During the two‐stage revision treatment of PJI patients, the use of ALCS may lead to the development of AKI, which could result in severe adverse outcomes. Despite the wide variation in the incidence of developing AKI reported in the literature, clinicians still need adequate attention, especially when confronting PJI patients who are elderly, obese ...
Lijun Cai, Xingxiao Pu, Yajie Chen, Guangtao Han, Qianhao Li, Qiuru Wang, Pengde Kang   +6 more
wiley   +1 more source

Delayed-type of hypersensitivity reaction due to piperacillin/tazobactam causing severe thrombocytopenia

National Journal of Physiology, Pharmacy and Pharmacology, 2016
Piperacillin/tazobactam is a frequently prescribed and well-tolerated β-lactam antibiotic used in various clinical conditions with favorable side effect profile.
Mihir Parekh, Sanket Sheth, Bhalendu Vaishnav, Anusha Mangalampalli   +3 more
doaj   +1 more source

Ionizable Lipid Containing Nanocarriers for Antimicrobial Agent Delivery

Small Science
Antimicrobial resistance (AMR) poses a global health crisis demanding innovative solutions. Traditional antibiotics, though pivotal over the past century in combating bacterial infections, face diminished efficacy against evolving bacterial defense ...
Haitao Yu, Sampa Sarkar, Z. L. Shaw, Brendan Dyett, Xudong Cai, Sue Lyn Yap, Charlotte E. Conn, Aaron Elbourne, Calum J. Drummond, Jiali Zhai   +9 more
doaj   +1 more source

A case report of severe drug-induced immune hemolytic anemia caused by piperacillin

Frontiers in Immunology
Piperacillin is a beta-lactamase inhibitor frequently used in the treatment of urinary tract infections. It is a broad-spectrum antibiotic with strong antibacterial action against Pseudomonas aeruginosa and Enterobacter, especially extended-spectrum beta-
Hong Zhao, Hong Zhao, Jian Chen, Jian Chen, Guojin Ou, Guojin Ou, Guojin Ou   +6 more
doaj   +1 more source

The reaction mechanism of metallo-beta-lactamases is tuned by the conformation of an active site mobile loop [PDF]

, 2018
Carbapenems are "last resort" β-lactam antibiotics used to treat serious and life-threatening health care-associated infections caused by multidrug-resistant Gram-negative bacteria.
Alzari, Pedro M., Bethel, Christopher R., Bonomo, Robert A., Giannini, Estefanía, Klinke, Sebastian, Llarrull, Leticia Irene, Mojica, María F., Otero, Lisandro Horacio, Palacios, Antonela Rocio, Taracila, Magdalena A., Vila, Alejandro Jose   +10 more
core   +1 more source

Etiology, pathogenesis and treatment of peri‐implantitis: A European perspective

Periodontology 2000, EarlyView.
Abstract Peri‐implantitis is a plaque‐associated pathological condition occurring in tissues around dental implants. It is characterized by inflammation in the peri‐implant mucosa and progressive loss of supporting bone. Over the last 30 years, peri‐implantitis has become a major disease burden in dentistry.
Tord Berglundh, Andrea Mombelli, Frank Schwarz, Jan Derks   +3 more
wiley   +1 more source