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Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry [PDF]

open access: yesChemistryOpen
Interest in piperazine scaffolds continues to rise due to their broad relevance across anti‐infective, anticancer, and neuroactive research. This review examines reports published from 2014 to 2024 and organizes current developments by therapeutic class,
Assel Ten   +5 more
doaj   +2 more sources

Synthesis, Characterization, Computational Studies, and Evaluation of Neuroprotective Effects of New Piperazine Compounds [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2021
The new piperazine-based Schiff base hydrazone with N, O donor set of atoms, LPE, has been prepared by the condensation reaction of new piperazine-based diamine, APE, with salicylaldehyde.
Malihe Erfantalab   +3 more
doaj   +1 more source

Development of heavy metal-based nanostructured complex technology for use in building mortar [PDF]

open access: yesНанотехнологии в строительстве, 2022
: Introduction. Heavy metals (copper, zinc, nickel, lead, chromium, cobalt, cadmium) get into constructional materials with natural and man-made raw materials.
Vladimir M. Ilin   +3 more
doaj   +1 more source

Synthetic route towards 1,2,3,4-tetrahydroquinoxaline/piperidine combined tricyclic ring system [PDF]

open access: yesJournal of the Serbian Chemical Society, 2022
The synthetic route toward novel tricyclic, nitrogen-containing system is disclosed. Three novel compounds possessing structural features of 1,2,3,4-tetrahydroquinoxaline and decahydropyrido[3,4-b]pyrazine are synthesized starting from readily available ...
Krunić Mihajlo J.   +3 more
doaj   +1 more source

Crystal structure and Hirshfeld surface analysis of the hydrated 2:1 adduct of piperazine-1,4-diium 3,5-dinitro-2-oxidobenzoate and piperazine

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2022
The crystal structure of the adduct piperazine-1,4-diium 3,5-dinitro-2-oxidobenzoate–piperazine–water (2/1/2) shows the existence of a 3,5-dinitrosalicylate dianion (DNSA2−) and a protonated piperazine-1,4-diium cation (PIP2+) along with a piperazine ...
Veerappan Subha   +4 more
doaj   +1 more source

Effective Removal of Acetaldehyde Using Piperazine/Nitric Acid Co-Impregnated Bead-Type Activated Carbon

open access: yesMembranes, 2023
Acetaldehyde (CH3CHO) in the atmosphere is associated with adverse health effects. Among the various options for use in removing CH3CHO, adsorption is often employed because of its convenient application and economical processes, particularly when using ...
Yu-Jin Kang   +7 more
doaj   +1 more source

5,5′-(Piperazine-1,4-diyl)bis(4-chloro-3H-1,2-dithiol-3-one)

open access: yesMolbank, 2022
Conjugates of 3H-1,2-dithiol-3-ones with various biologically active compounds are intensively investigated. Although many derivatives of this class have been described in the literature, the compounds containing two dithiole cycles have been explored ...
Vladimir A. Ogurtsov, Oleg A. Rakitin
doaj   +1 more source

Oxidation of some Alicyclic Amines by Potassium Hexacyanoferrate (III) in Alkaline Medium: A Kinetic and Mechanistic Study [PDF]

open access: yesمجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2001
Oxidation of some alicyclic amines (morpholine, piperazine and piperidine) by potassium hexacyanoferrate(???) in basic medium has been investigated at 35°C.
M. M. Al-Subu   +4 more
doaj   +1 more source

Electrochemical Oxidation Products of Piperazine as Corrosion Inhibitor for HP13Cr Steel in 20% HCl Solution

open access: yesInternational Journal of Electrochemical Science, 2019
Three products are synthesized by adjusting current density and quantity of ionic liquid [Bmim][PF6] in electrochemical oxidation of piperazine. The molecular structures of N-methoxyl piperazine, N- carbonyl piperazine and N, N’-dicarbonyl piperazine are
Jun Zhao   +7 more
doaj   +1 more source

Determination of the Primary Molecular Target of 1,2,4-Triazole-Ciprofloxacin Hybrids [PDF]

open access: yes, 2015
We have synthesized and examined the antibacterial activity, toxicity and affinity towards bacterial type II topoisomerases of a series of 1,2,4-triazole-ciprofloxacin hybrids.
Agata Paneth   +12 more
core   +2 more sources

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