Results 141 to 150 of about 73,428 (238)
Archiv der Pharmazie, Volume 359, Issue 3, March 2026.In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi +17 more
wiley +1 more source
Macromolecular Chemistry and Physics, Volume 227, Issue 5, 13 March 2026.Cationic poly(2‐oxazoline)s (POx) have emerged as versatile materials for different biomedical applications. The combination of the pseudo‐peptidic polymer backbone and the amine‐derived cationic motifs results in well‐tolerated polymers with potential benefits for drug and gene delivery as well as antimicrobial development.
Meike N. Leiske
wiley +1 more source
Journal of Peptide Science, Volume 32, Issue 3, March 2026.Discovery, evolution and potential future applications of bismuth bicycle molecules—a novel class of therapeutics with unique properties. ABSTRACT Bicyclic peptides are emerging as next generation therapeutics by combining the affinity and specificity of antibodies with the synthetic convenience of small molecules.
Saan Voss +8 more
wiley +1 more source
Rare Metals, Volume 45, Issue 3, March 2026.ABSTRACT Against the backdrop of global clean energy transition and surging demand for lithium resources, lithium extraction from salt lakes presents unprecedented development opportunities. Nanofiltration (NF) membrane technology, recognized for its efficiency, energy savings, and environmental benefits, demonstrates significant application potential ...
Wen‐Feng Li +5 more
wiley +1 more source
Bifunctional dithiocarbamates: a bridge between coordination chemistry and nanoscale materials
, 2009 Cowley, AR +3 more
core +1 more source
Small Science, Volume 6, Issue 3, March 2026.This study examines how the physico‐chemical properties of gold nanorods (AuNR) influence their interactions with human immune cells. Antibody‐targeted AuNR selectively bind and induce apoptosis in T‐lymphocytes during photothermal therapy. In contrast, neutrophils have a high intrinsic phagocytic capacity and the design of selective particles requires
Tista Roy Chaudhuri +12 more
wiley +1 more source
Drug Product Development of Lipid Nanoparticle‐Based mRNA Therapeutics and Vaccines
WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 2, March/April 2026.Overview of the development path from an mRNA–lipid nanoparticle (LNP) concept to a licensed drug product, covering LNP design, manufacturing process development, formulation, and analytical characterization. ABSTRACT Lipid nanoparticles (LNP) are currently the most relevant non‐viral delivery systems for mRNA and occasionally for smaller nucleic acids
Gideon Kersten +4 more
wiley +1 more source
Conformational Preferences and Benchmarking of Computational Methods for Piperazine-Based Ligands. [PDF]
ACS OmegaRincón DA, Zaorska E, Malinska M.
europepmc +1 more source
Spreading depolarization and its influence on epileptiform activity
Epilepsia, Volume 67, Issue 3, Page 1078-1089, March 2026.Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque +2 more
wiley +1 more source