Results 231 to 240 of about 37,689 (286)

Stereospecific Synthesis of Highly Substituted Piperazines via an One-Pot Three Component Ring-Opening Cyclization from N-Activated Aziridines, Anilines, and Propargyl Carbonates.

Journal of Organic Chemistry, 2018
A simple and efficient one-pot three-component synthetic route to highly substituted and functionalizable piperazines in high yields with excellent stereoselectivity (de, ee >99%) is reported.
N. Chauhan, Sajan Pradhan, M. Ghorai
semanticscholar   +1 more source

Synthesis, in vitro cytotoxicity and biological evaluation of twenty novel 1,3-benzenedisulfonyl piperazines as antiplatelet agents.

Bioorganic & Medicinal Chemistry, 2021
Xiu‐jie Liu, Yan Wang, Xiao Wang, Zhihao Zhang   +3 more
semanticscholar   +1 more source

Piperazine in the Treatment of Enterobiasis

Archives of Pediatrics & Adolescent Medicine, 1955
Enterobiasis is the most common helminth infestation in the United States. The pinworm has proved to be a difficult parasite to eradicate for the human race. Although reports of therapeutic agents have filled the medical literature throughout the years, not one drug has been universally accepted.
M H, RACHELSON, W R, FERGUSON
openaire   +2 more sources

Substituted Sulfonyl Piperazines

Journal of Pharmaceutical Sciences, 1962
Abstract In view of reports in the literature on the anticonvulsant action of various sulfonyl piperazines and of certain substituted 1-sulfonyl-4- β -aminoethylpiperazines as antishock agents, a series of mono- and disulfonyl β -aminoethylpiperazines have been prepared.
W E, LANGE, R N, LAZARUS, M E, AMUNDSON
openaire   +2 more sources

Derivatives of Piperazine. XXI. Synthesis of Piperazine and C-Substituted Piperazines

Journal of the American Chemical Society, 1947
L J, KITCHEN, C B, POLLARD
openaire   +2 more sources

Piperazine toxicity

Veterinary Record, 1987
openaire   +4 more sources

Piperazine

2000
Abstract Salts of piperazine, a cyclic secondary amine, were introduced into clinical medicine in the 1880s for the treatment of gout and other rheumatic disorders; they were found in the 1950s to have anthelmintic activity (3-5). Piperazine is used for the treatment of intestinal infestation with Ascaris lumbricoides (roundworm) and ...
openaire   +1 more source

Piperazine

Reactions Weekly, 2014
A.M. Molina López, M.R. Moyano Salvago
openaire   +2 more sources

Therapy of Ascariasis with Piperazine

The American Journal of Tropical Medicine and Hygiene, 1955
Summary The following cure rates were achieved in Ascaris lumbricoides infections with piperazine citrate syrup: one day treatment, 74 per cent; two days, 94 per cent. A five day course with smaller daily doses but a larger total amount gave a cure rate of 91 per cent. A minor toxic side effect, possibly due to the drug, was observed in only one of 136
openaire   +2 more sources

Piperazine

2021
openaire   +2 more sources