Results 201 to 210 of about 84,342 (322)

Exploring CPP Enhanced Hypoxia Targeting: An Approach Using Radiolabeled 2‐nitroimidazole TAT Conjugate

Drug Development Research, Volume 87, Issue 1, February 2026.
ABSTRACT Mediated by their protein transduction domain, cell‐penetrating peptides (CPPs) have been widely explored for facilitating intracellular delivery of drugs and small molecules. In this study, a radiolabeled, 2‐nitroimidazole conjugated TAT (TAT ‐ transactivator of transcription) peptide was prepared and evaluated for targeting tumor hypoxia ...
Sweety Mittal, Akanksha Jain, Ashwini Babu, Chandan Kumar, Madhava B. Mallia   +4 more
wiley   +1 more source

A dicationic ionic liquid strategy to enhance the thermal stability of manganese bromide scintillators. [PDF]

Chem Sci
Chen GY, Lin HW, Ablez A, Guo XP, Ren YW, Luo JH, Zou QH, Du KZ, Wang ZP, Huang XY.   +9 more
europepmc   +1 more source

Synthesis of N-Substituted 1,6-Dihydro-3(2H)-pyridinones and 1-Acyl-3-piperidines

, 1984
Ling-Ching Chen, Eng-Chi Wang, Jen‐Hom Lin, S S Wu   +3 more
openalex   +1 more source

Preparation and characterization of some Transition Metal Complexes the first and second with (1-methyl-3-Piperidine Xanthate potassium) and ethylenediamine

, 2023
Fayhaa K.Al-Garah
openalex   +2 more sources

Expanding Access to Opioid Use Disorder Treatment: Low‐Threshold Buprenorphine Dispensing via an Interprofessional Mobile Medical Unit in Chicago

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 2, February 2026.
ABSTRACT Background Less than 25% of individuals with opioid use disorder access medication treatment. Lower income and segregated Black and Hispanic communities often have little to no access to services. In 2021, the Drug Enforcement Administration authorized opioid treatment programs to add mobile units to their licensure, extending treatment to ...
Abigail T. Elmes‐Patel, Jennie B. Jarrett, Antonio D. Jimenez, Stockton M. Mayer, Sarah E. Messmer   +4 more
wiley   +1 more source

Allosteric targeting of RIPK1: discovery of novel inhibitors <i>via</i> parallel virtual screening and structure-guided optimization. [PDF]

RSC Med Chem
Vijayan RSK, Hamilton MM, Pfaffinger DE, Alvarez FG, Reyna NJ, Bardenhagen JP, Shepard H, Rodriguez C, Goodwani S, Lightfoot Y, Maskos K, Johannsson S, Kempf G, Xu QA, Neumann L, Jiang Y, Do MG, Jones P, Lewis RT, Ray WJ, Cross JB.   +20 more
europepmc   +1 more source

Conversion of 3-Substituted Piperidines and Pyridines into the Corresponding N-(3,4-Dimethoxyphenethyl)lactams: A Comparative Study of the Mercuric Acetate-EDTA and the Ferricyanide Oxidation Methods

, 1975
Tozo Fujii, Masashi Ohba, Shigeyuki Yoshifuji   +2 more
openalex   +1 more source

Structural Insights Into the Nuclear Import of Gallid Alphaherpesvirus 1 Large Tegument Protein

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
The study identifies and characterizes a bipartite nuclear localization signal within the GaAHV‐1 UL36 large tegument protein, revealing its structural interaction with importin α/β1 and confirming a conserved mechanism of nuclear import through biochemical, crystallographic, and mutational analyses.
Babu Kanti Nath, Crystall M. D. Swarbrick, Reuben Blades, Daryl Ariawan, Ole Tietz, Gualtiero Alvisi, Jade K. Forwood, Subir Sarker   +7 more
wiley   +1 more source

Novel Sulfonium Reagents for the Modular Synthesis of Spiro[2.3]Hexanes and Heteroatom‐Containing Analogues: Synthesis, Application, and Evaluation as Bioisosteres

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
Strained spirocyclic spiro[2.3]hexane and its heteroatom‐containing derivatives, including previously underrepresented 5‐oxa‐1‐azaspiro[2.3]hexanes and 1,5‐diazaspiro[2.3]hexanes, were synthesized via a modular approach of insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into alkenes, carbonyls and imines.
Philipp Natho, Annarita Vicenti, Fabrizio Mastrolorito, Francesca De Franco, Lee Walsh‐Benn, Marco Colella, Ernesto Mesto, Emanuela Schingaro, Orazio Nicolotti, Antimo Gioiello, Renzo Luisi   +10 more
wiley   +2 more sources

Thiazolidinones: novel insights from microwave synthesis, computational studies, and potentially bioactive hybrids. [PDF]

Beilstein J Org Chem
Martinho LA, Praciano VHJG, Matos GDR, Gatto CC, Andrade CKZ.   +4 more
europepmc   +1 more source