Results 191 to 200 of about 103,451 (274)

Development of a SIN1 targeting inhibitor as a novel therapeutic approach for the treatment of malignancies. [PDF]

Mol Cancer Ther
Beauchamp EM, Jain A, Clutter M, Nahotko D, Lopez Fajardo E, Vagadia PP, Dunne SF, Mina A, Fischietti M, Oku CV, Blyth GT, Mishra RK, Karras E, Radecki SG, Lantz C, Addepalli S, Modi M, Zou L, Cho BK, Goo YA, Rossoff J, Fish EN, Saleiro D, Schiltz GE, Platanias LC.   +24 more
europepmc   +1 more source

Novel Sulfonium Reagents for the Modular Synthesis of Spiro[2.3]Hexanes and Heteroatom-Containing Analogues: Synthesis, Application, and Evaluation as Bioisosteres. [PDF]

Angew Chem Int Ed Engl
Natho P, Vicenti A, Mastrolorito F, De Franco F, Walsh-Benn L, Colella M, Mesto E, Schingaro E, Nicolotti O, Gioiello A, Luisi R.   +10 more
europepmc   +1 more source

Allosteric targeting of RIPK1: discovery of novel inhibitors <i>via</i> parallel virtual screening and structure-guided optimization. [PDF]

RSC Med Chem
Vijayan RSK, Hamilton MM, Pfaffinger DE, Alvarez FG, Reyna NJ, Bardenhagen JP, Shepard H, Rodriguez C, Goodwani S, Lightfoot Y, Maskos K, Johannsson S, Kempf G, Xu QA, Neumann L, Jiang Y, Do MG, Jones P, Lewis RT, Ray WJ, Cross JB.   +20 more
europepmc   +1 more source

Application of the OBIMAP (One-Bead Interchain Multipeptide Assembly Platform) to Long Peptide Synthesis: Liraglutide as a Case Study. [PDF]

ACS Omega
AlShaer D, Al Musaimi O, Williams DR.
europepmc   +1 more source

Computational Chemistry Advances in the Development of PARP1 Inhibitors for Breast Cancer Therapy. [PDF]

Pharmaceuticals (Basel)
Twala C, Govender P, Govender K.
europepmc   +1 more source

Thiazolidinones: novel insights from microwave synthesis, computational studies, and potentially bioactive hybrids. [PDF]

Beilstein J Org Chem
Martinho LA, Praciano VHJG, Matos GDR, Gatto CC, Andrade CKZ.   +4 more
europepmc   +1 more source

Isoniazid-Derived Hydrazones Featuring Piperazine/Piperidine Rings: Design, Synthesis, and Investigation of Antitubercular Activity. [PDF]

Biomolecules
Özcan E, Vagolu SK, Tamhaev R, Lherbet C, Mourey L, Tønjum T, Gündüz MG, Doğan ŞD.   +7 more
europepmc   +1 more source

Rational design and antibacterial assessment of novel pyranopyrazole derivatives: a combined experimental and in silico study. [PDF]

Sci Rep
Abdelatty MM, Makhlouf AA, Moustapha ME, Yossef AM, Farag ZR.   +4 more
europepmc   +1 more source

Piperidine derivatives.

Bulletin of the World Health Organization, 2010
openaire   +1 more source