Results 181 to 190 of about 38,750 (255)

B(C₆F₅)₃-Catalyzed Chemical Tagging of Bioactive <i>N</i>-Alkylamines through β-Amino C(sp³)-H Functionalization. [PDF]

Org Lett
Chapman M, Dai C, Wang Y, Zhao C, Pham Q, Chatterjee A, Wasa M.   +6 more
europepmc   +1 more source

Selective Rh(II)‐Catalyzed Intermolecular Oxyamidation and Acid‐Promoted Nucleophilic Cyclization Cascade of Enamides

ChemistryEurope, Volume 4, Issue 6, June 2026.
A structurally diverse series of 1‐amino‐izidine scaffolds was accessed through a cascade process combining rhodium‐catalyzed nitrene‐transfer oxyamidation with subsequent nucleophilic cyclization under acidic conditions, proceeding via an in situ generated iminium intermediate.
Grégory Jestin, Romain Rey‐Rodriguez, Romane Manguin, Pascal Retailleau, Philippe Dauban, Isabelle Gillaizeau   +5 more
wiley   +1 more source

Crystal structures of (<i>S</i>)-3-{1-[(4-chloro-phen-yl)sulfon-yl]piperidin-2-yl}pyridine, (<i>S</i>)-3-[1-(4-methyl-phen-yl)piperidin-2-yl]pyridine, (<i>S</i>)-3-{1-[(4-meth-oxy-phen-yl)sulfon-yl]piperidin-2-yl}pyridine and (<i>S</i>)-3-{1-[(3,4-di-methyl-phen-yl)sulfon-yl]piperidin-2-yl}pyridine. [PDF]

Acta Crystallogr E Crystallogr Commun
Okmanov RY, Olimova MI, Yuldashova IE, Azimova GZ, Pulatova FA.   +4 more
europepmc   +1 more source

Multifaceted Lewis Acidity of a High‐Valent Cu(III) Hydroxide Complex

ChemistryEurope, Volume 4, Issue 6, June 2026.
Novel reactivity of a Cu(III) trifluoromethyl hydroxide tetramer as a multifaceted Lewis acid is demonstrated. Treatment with strong Lewis bases leads to binuclear Cu(III) hydroxide bridged scaffolds, whereas capped cubanes are formed with solvents and halide anions.
Vladimir Motornov, Niklas Limberg, Alexandre Millanvois   +2 more
wiley   +1 more source

Photoredox-enabled late-stage functionalization of pyrrolidines in batch and flow: rapid access to benzothiazole hybrids as a new class of cholinesterase inhibitors. [PDF]

RSC Adv
Filipović A, Vučkovski M, Mićović D, Bondžić AM, Bondžić BP.   +4 more
europepmc   +1 more source

Structural‐to‐Functional Complexity Transformations Enabled by Bridged Polyheterocycles: Access to Cis‐1,3‐Diamines and Amino‐Alcohols

ChemistryEurope, Volume 4, Issue 6, June 2026.
Polycyclic intermediates enable stereocontrolled synthesis of densely functionalized cis‐1,3‐diamine and amino alcohol carbocycles and heterocycles via structural‐to‐functional complexity transformations from low‐complexity starting material. Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products ...
Jiayi Zhu, Erica Benedetti, Laurent Micouin   +2 more
wiley   +1 more source

An Imidazo[2,1-b][1,3,4]thiadiazole Derivative Inhibits the Virulence Factor α-Hemolysin by Blocking the Pullout of Its Stem Domain. [PDF]

ChemMedChem
Korotkov VS, Lukat P, Di Lucrezia R, Shekhar A, Degenhart C, Diestel R, Bilitewski U, Dinkel K, Blankenfeldt W, Brönstrup M.   +9 more
europepmc   +1 more source

Method for Reductive N‐Alkylation of a Secondary Amine With an Aldehyde at Room Temperature Through Utilization of an Imine Reductase

Chemistry–Methods, Volume 6, Issue 6, June 2026.
An organic‐synthetic method for smooth N‐alkylation of a secondary amine with an aldehyde as reagents and glucose as a reducing agent in aqueous medium has been developed, exemplified for the N‐benzylation of 2‐methylpyrrolidine. This transformation proceeds through enzyme catalysis with an imine reductase as a biocatalyst and a glucose dehydrogenase ...
Kateryna Zelenska, Harald Gröger
wiley   +1 more source

Organo-catalyzed deamination of polystyrene sulfonamide for diverse post-polymerization modification of styrenic polymers.

Polym Chem
Shrestha T, Nguyen DM, Goehrig H, Damani VS, Quinn CM, Kayser LV.   +5 more
europepmc   +1 more source

Structural modification of 5-alkyl-4-phenyl-thiazole-based fatty acid amide hydrolase and soluble epoxide hydrolase inhibitors to alleviate orofacial inflammatory pain in the rat. [PDF]

BBA Adv
Gorostiza G, Mercado M, Pavana L, Carr D, Yuan C, Tsang A, Gomez K, Minton I, Carrillo D, Berumen M, Pecic S, Kandasamy R.   +11 more
europepmc   +1 more source