Results 181 to 190 of about 11,531 (247)

Off‐Label Initiation of Gabapentin and Valproic Acid Among Long‐Stay Nursing Home Residents With and Without Dementia

Journal of the American Geriatrics Society, EarlyView.
Lauren B. Gerlach, Lan Zhang, Ana Montoya, Sarah L. Krein, Andrew R. Zullo, Julie P. W. Bynum, Donovan Maust   +6 more
wiley   +1 more source

Dearomative spirocyclization of ynamides. [PDF]

Chem Sci
Agbaria M, Egbaria N, Nairoukh Z.
europepmc   +1 more source

Flipping the Card With Enantiodivergent Organocatalysis

Chemistry – A European Journal, Volume 32, Issue 29, 7 August 2026.
This minireview elaborates on recent organocatalytic strategies for achieving enantiodivergence—the ability to access both product enantiomers using a single chiral catalyst. It highlights how achiral stimuli, such as solvent polarity and chemical additives, along with minimal catalyst modifications, trigger stereochemical inversions in reactions ...
Debora Iapadre, Alessio Carioscia, Alessandro Brusa, Armando Carlone   +3 more
wiley   +1 more source

Synthesis of Chiral Saturated Heterocycles Bearing Quaternary Centers via Enantioselective β-C(sp³)-H Activation of Lactams. [PDF]

J Am Chem Soc
Lu P, Burgenson WR, Simmons BJ, Liu S, Yeung KS, Qiao JX, Yu JQ.   +6 more
europepmc   +1 more source

Comparative <i>in vitro</i> efficacy of aztreonam-avibactam and other alternatives (cefepime-taniborbactam, cefepime-zidebactam, and cefiderocol) against metallo-β-lactamase-producing Enterobacterales isolated in 2024 in France. [PDF]

Antimicrob Agents Chemother
Emeraud C, Dutkiewicz M, Dortet L.
europepmc   +1 more source

Hypervalent iodine-mediated intramolecular alkene halocyclisation. [PDF]

Beilstein J Org Chem
Bansal C, Ruggles O, Rowett AC, Lennox AJJ.   +3 more
europepmc   +1 more source

HOF‐Stabilized Apple EV Nanocargo in an NIR‐Responsive Hydrogel Enables On‐Demand Therapeutic Modulation for Transdermal Deep‐Joint Osteoarthritis Therapy

Advanced Healthcare Materials, Volume 15, Issue 29, 7 August 2026.
An NIR‐responsive transdermal hydrogel integrating apple EV nanocargo, berberine, piperine, HOFs, and graphene oxide enables localized osteoarthritis modulation. The platform supports enhanced transdermal delivery together with mild hyperthermia‐associated and redox‐related responses, leading to reduced inflammation and oxidative stress, improved ...
Yu‐Wen Tseng, Pei‐Wei Weng, Hsien‐Tsung Lu, Jiunn‐Horng Kang, Lekha Rethi, Lekshmi Rethi, Yan‐Ting Chen, Hieu Trung Nguyen, Yao‐Tung Tsai, Andrew E.‐Y. Chuang   +9 more
wiley   +1 more source

Design, Synthesis and Biological Evaluation of Medicinal Potential Compounds. [PDF]

Molecules
Boto REF, Almeida P, Silvestre SM.
europepmc   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, Volume 15, Issue 29, 7 August 2026.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source

A Brønsted acid-base approach for the net monoselective C-F substitution of (trifluoromethyl)alkanes. [PDF]

Chem Sci
Coradi NJ, Bandar JS.
europepmc   +1 more source