Results 171 to 180 of about 40,681 (241)

Synthesis and crystal structure of piperidinyl propanenitrile towards the preparation of piperidine based bioactive films for drug delivery applications. [PDF]

Sci Rep
Mohamed-Ezzat RA, Hasanin MS, Kariuki BM, Dacrory S.   +3 more
europepmc   +1 more source

Piperidine derivatives.

Bulletin of the World Health Organization, 2010
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Catalytic Access to Bridged Sila-N-heterocycles from Piperidines via Cascade sp3 and sp2 C–Si Bond Formation

Journal of the American Chemical Society, 2018
Described herein is the development of an unprecedented route to bridged sila- N-heterocycles via B(C6F5)3-catalyzed cascade silylation of N-aryl piperidines with hydrosilanes. Mechanistic studies indicated that an outer-sphere ionic path is operative to
Jianbo Zhang, Sehoon Park, Sukbok Chang   +2 more
exaly   +2 more sources

Harnessing the Electrophilicity of Keteniminium Ions: A Simple and Straightforward Entry to Tetrahydropyridines and Piperidines from Ynamides

Angewandte Chemie - International Edition, 2016
An efficient, modular and straightforward entry to tetrahydropyridines and piperidines is reported. This reaction is based on a formal intramolecular hydroalkylation of readily available, properly substituted ynamides which, upon simple activation under ...
Morgan Lecomte, Gwilherm Evano
exaly   +2 more sources

Multicomponent synthesis of highly functionalized piperidines

Synthetic Communications, 2020
Highly functionalized piperidines are a versatile class of nitrogen-containing heterocycles which find broad applications in numerous fields such as medicinal chemistry and drug discovery research.
Leili Shaker Ardakani, Arash Arabmarkadeh, M. Kazemi   +2 more
semanticscholar   +1 more source

Transition‐Metal‐Free Deconstructive Lactamization of Piperidines

Angewandte Chemie - International Edition, 2019
One of the major challenges in organic synthesis is the activation or deconstructive functionalization of unreactive C(sp3 )-C(sp3 ) bonds, which requires using transition or precious metal catalysts.
Silvano Cruz-Gregorio, Jacinto Sandoval-Lira, Julio M Hernández-Pérez   +2 more
exaly   +2 more sources

Highly Diastereoselective Synthesis of Medium-Sized Carbocycle-Fused Piperidines via Sequential Hydride Shift Triggered Double C(sp3)-H Bond Functionalization.

Organic Letters, 2019
Herein we report a diastereoselective synthesis of medium-sized carbocycle-fused piperidines via [1,n (n = 6, 7)]-[1,5]-sequential hydride shift triggered double C(sp3)-H bond functionalization.
Miyabi Kataoka, Yuna Otawa, Natsuki Ido, K. Mori   +3 more
semanticscholar   +1 more source

Regio- and Diaseteroselective Synthesis of Polysubstituted Piperidines Enabled by Boronyl Radical-Catalyzed (4+2) Cycloaddition.

Angewandte Chemie
Piperidines are widely present in small molecule drugs and natural products. Despite many methods have been developed for their synthesis, new approaches to polysubstituted piperidines are highly desirable.
Z. Ding, Zhijun Wang, Yingying Wang, Xicheng Wang, Yuanji Xue, Ming Xu, Hailong Zhang, Liang Xu, Pengfei Li   +8 more
semanticscholar   +1 more source

Synthesis of Piperidines

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source