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Chemoenzymatic Synthesis of Chiral Piperidines Using the Immobilized Transaminase ATA‐117 in Continuous Flow Reactors

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
A robust continuous flow chemoenzymatic process was developed for the stereoselective synthesis of cis‐(2R,6R)‐2,6‐disubstituted piperidines, including the natural alkaloid (–)‐pinidinone. The asymmetric transamination of α,β‐unsaturated ketones was catalyzed by immobilized ATA‐117, followed by spontaneous aza‐Michael cyclization, providing the desired
Sara Vicinanza   +11 more
wiley   +1 more source

Reductive Transamination of Pyridinium Salts to N-Aryl Piperidines. [PDF]

open access: yesJ Org Chem
Chen Z   +8 more
europepmc   +1 more source

The Use of Piperidinium Surfactants in Nematicide Formulations. [PDF]

open access: yesMolecules
Kushnazarova R   +6 more
europepmc   +1 more source
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Stereoselective Synthesis of Piperidines

Synthesis, 2000
Sabine Laschat
exaly  

PIPERIDINE DERIVATIVE

2009
HIGASHIURA KUNIHIKO   +3 more
openaire   +7 more sources

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