Results 201 to 210 of about 25,392 (338)

REILLY PIPERIDINES [PDF]

Chemical & Engineering News Archive, 1962
openaire   +1 more source

Influence of Peptide‐Based Chelator Sequences on HER2‐Targeting Radiopeptide

Journal of Peptide Science, Volume 32, Issue 5, May 2026.
Peptide‐based chelator consisting of Cys‐Gly‐Gly‐Gly incorporated into HER2‐targeting rL‐A9 peptide for 99mTc‐labeling. [99mTc]Tc‐CGGG‐rL‐A9 exhibited high binding affinity and tumor uptake and retention. ABSTRACT In our pursuit of developing HER2‐targeting radiolabeled peptides for detection and therapy of HER2‐positive breast cancer, the previously ...
Sonal Gupta, Manoj Kumar, Krishna Mohan Repaka, Amit Das, Ajit A. Kengar, Drishty Satpati   +5 more
wiley   +1 more source

[Expression of Concern] Halofuginone induces the apoptosis of breast cancer cells and inhibits migration via downregulation of matrix metalloproteinase‑9. [PDF]

Int J Oncol
Jin ML, Park SY, Kim YH, Park G, Lee SJ.
europepmc   +1 more source

Gaining insights into MmpL3: combining structural and computational approaches to unlock transport and inhibitor‐binding mechanisms

Acta Crystallographica Section D, Volume 82, Issue 5, Page 550-570, May 2026.
This study investigates the mycobacterial membrane protein MmpL3, a key target for new antituberculosis drugs, by combining high‐resolution crystallography and computational simulations. It reveals how the inhibitor UPAR‐1109 binds to MmpL3, providing detailed insights into the function and flexibility of the protein and supporting the rational design ...
Satoshi Murakami, Domenico Marson, Eiki Yamashita, Bruno Broshka, Ui Okada, Maho Aoki, Giannamaria Annunziato, Erik Laurini, Emanuele Carosati, Marco Pieroni   +9 more
wiley   +1 more source

Multimodal Approach for Recalcitrant Melasma Using Picosecond Laser and Topical JAK Inhibition: A Case Report. [PDF]

J Cosmet Dermatol
Ashkanani H, AlZaabi M, AlRasheed A, AlDaraji W.   +3 more
europepmc   +1 more source

Efficient Synthesis of Spiro[Piperidine-4,3'-Pyrrolo[3,4-C]Quinolines Via 1,3-Dipolar Cycloaddition of Azomethine Ylides and 3-Nitro-2(1h)-Quinolones

Márk Molnár, Tamás Gáti, Attila Bényei, Miklós Nyerges   +3 more
openalex   +1 more source

THE INFLUENCE OF STERIC AND ORBITAL INTEREACTIONS ON MOLECULAR STRUCTURE IN N-SUBSTITUTED PIPERIDINES

, 2016

openalex   +1 more source

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

British Journal of Pharmacology, Volume 183, Issue 9, Page 1845-1859, May 2026.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim, Junhyuk Woo, Sungmin Pak, Joonho Paik, Gyu‐Sang Hong, Ji Hun Wi, Sanghee Lee, Cristina Fenollar‐Ferrer, Kyungreem Han, Young Kee Shin, Uhtaek Oh   +10 more
wiley   +1 more source

Chiron approaches to polyhydroxylated piperidines: promising glycosidase inhibitors

ARKIVOC, 2002
Dilip D. Dhavale, Vijaya N. Desai, Nabendu N. Saha, Jayant N. Tilekar   +3 more
doaj   +1 more source

Transaminase-Triggered Cascades for the Synthesis and Dynamic Kinetic Resolution of Chiral N-Heterocycles. [PDF]

Angew Chem Int Ed Engl
O'Connell A, Haarr MB, Ryan J, Xu X, Martin A, Smith SN, Elghobashi-Meinhardt N, Fleming P, Maciá B, Caprio V, O'Reilly E.   +10 more
europepmc   +1 more source