Results 271 to 280 of about 24,641 (321)

Dearomative Cyclization of Ynamides toward the Formation of Fused Diazabicycles. [PDF]

Org Lett
Agbaria M, Nairoukh Z.
europepmc   +1 more source

Regulierung der Promiskuitiven Katalyse durch Substratinduzierte Transiente Assemblierung

Angewandte Chemie, Volume 138, Issue 1, 2 January 2026.
Wir berichten über eine neuartige substratinduzierte transiente Koassemblierung zwischen einem kurzen lysinreichen Peptid und Fmoc‐Gly‐OH. Im aktivierten Zustand zeigt die Assemblierung eine promiskuitive katalytische Aktivität durch die Beschleunigung der Hydrolyse und der C═N‐Kondensationsreaktion.
Ayan Chatterjee, Maximilian Schuler, Marius G. Braun, Christopher V. Synatschke, Qi Lu, Jiyao Yu, David Y. W. Ng, Tanja Weil   +7 more
wiley   +1 more source

Treatment of transplantation-associated thrombotic microangiopathy with iptacopan: two cases report. [PDF]

Ann Hematol
Kong J, Tian Z, Deng DX, Mo XD.
europepmc   +1 more source

Genetische Codierung von Pentafluorphosphato‐Phenylalanin ermöglicht die Herstellung von PF5‐Proteinen als Phosphoprotein‐Mimetika

Angewandte Chemie, Volume 138, Issue 1, 2 January 2026.
Erweiterung des genetischen Codes mit einem einzigartigen hyperfluorierten Phosphotyrosin‐Analogon. In dieser Arbeit haben wir die nicht‐natürliche Aminosäure Pentafluorphosphato‐Difluormethyl‐Phenylalanin, die sieben Fluoratome und eine permanente negative Ladung trägt, mittels mutierter, orthogonaler Aminoacyl‐tRNA‐Synthetasen erfolgreich in drei ...
Anna Magdalena Ambros, Haocheng Qianzhu, Markus Tiemann, Edan Habel, Katrin Denzinger, Hana Zupan, Matteo Accorsi, Bettina G. Keller, Gerhard Wolber, Thomas Huber, Jörg Rademann   +10 more
wiley   +1 more source

A case of vitiligo secondary to discoid lupus erythematosus treated with tofacitinib. [PDF]

Medicine (Baltimore)
Jin S, Wang S, Jin S, Tang C, Wang P.
europepmc   +1 more source

Regulating Promiscuous Catalysis via Substrate‐Induced Transient Assembly

Angewandte Chemie International Edition, Volume 65, Issue 1, 2 January 2026.
We report a novel substrate‐induced transient co‐assembly between a short Lys‐rich peptide and Fmoc‐Gly‐OH. In the activated state, the assembly exhibits promiscuous catalytic activity through the rate enhancements of hydrolysis and C═N condensation reactions.
Ayan Chatterjee, Maximilian Schuler, Marius G. Braun, Christopher V. Synatschke, Qi Lu, Jiyao Yu, David Y.W. Ng, Tanja Weil   +7 more
wiley   +1 more source

Efficacy of BTK inhibitor combined with rituximab and lenalidomide in newly diagnosed diffuse large B-cell lymphoma: a single-center, retrospective study. [PDF]

Ann Hematol
Lv Y, Zhu Y, Yang C, Zhang X, Zhang X, Wei J, Ye X, Xu G, Mao L, Mai W, Yang M, Qian J, Tong H, Jin J, Yu W.   +14 more
europepmc   +1 more source

Genetic Encoding of Pentafluorophosphato‐Phenylalanine Provides PF5‐Proteins as Phosphoprotein Mimetics

Angewandte Chemie International Edition, Volume 65, Issue 1, 2 January 2026.
Genetic code expansion with a unique hyper‐fluorinated phosphotyrosine analog. In this work, we successfully incorporated the unnatural amino acid pentafluorophosphato‐difluoromethyl‐phenylalanine, carrying seven fluorine atoms and a permanent negative charge into three different proteins via the use of mutated orthogonal aminoacyl‐tRNA synthetases ...
Anna Magdalena Ambros, Haocheng Qianzhu, Markus Tiemann, Edan Habel, Katrin Denzinger, Hana Zupan, Matteo Accorsi, Bettina G. Keller, Gerhard Wolber, Thomas Huber, Jörg Rademann   +10 more
wiley   +1 more source

Stereocontrolled four-carbon homologation of vicinally functionalized allylic pyrrolidines to highly customized azonines bearing remote benzylic stereocenters. [PDF]

RSC Adv
Beng TK, Johnsen A, Gitonga A, Kaur J.
europepmc   +1 more source

Imaging of Lipid Droplets in Living Cells and Mice with Metabolic Dysfunction‐Associated Steatotic Liver Disease via a Galactose‐Modified Supramolecular Near‐Infrared Fluorescent Glycoprobe

Advanced Functional Materials, Volume 36, Issue 3, 8 January 2026.
A galactose‐modified supramolecular near‐infrared (NIR) glycoprobe, TCF‐FBN@Gal‐BSA, enables targeted delivery to the liver through the asialoglycoprotein receptor (ASGPR) and facilitates liver‐targeting fluorescence visualization of lipid droplets (LDs) in metabolic dysfunction‐associated steatotic liver disease (MASLD) mice.
Han‐Min Wang, Lei Dong, Qiu‐Lian Hao, Lu‐Lu Sun, Xin‐Rong Li, Yu‐Wei Yuan, Ming‐Ye Tang, Jin Gong, Yi Zang, Jia Li, Tony D. James, Xiao‐Peng He, Hai‐Hao Han   +12 more
wiley   +1 more source