Results 291 to 300 of about 40,506 (345)

Synthesis of 2-Unsubstituted Pyrrolidines and Piperidines from Donor-Acceptor Cyclopropanes and Cyclobutanes: 1,3,5-Triazinanes as Surrogates for Formylimines.

Journal of Organic Chemistry, 2017
A synthetic procedure to access 2-unsubstituted pyrrolidines and piperidines is presented. In the presence of MgI2 as Lewis acid, donor-acceptor cyclopropanes or corresponding cyclobutanes were treated with 1,3,5-triazinanes, leading to the five- or six ...
L. K. B. Garve, A. Kreft, P. Jones, D. Werz   +3 more
semanticscholar   +1 more source

2-cyano Δ3 piperidines IV: Spiroannelation in the piperidine series

Tetrahedron Letters, 1981
Abstract The preparation of piperidines 7 and 11 spirosubstituted at C-2 from the 2-cyano Δ3 piperidine 5 is described. The mechanism of their formation is discussed.
H. Harris, H.-P. Husson, David S. Grierson   +2 more
openaire   +2 more sources

ChemInform Abstract: Stereoselective Synthesis of Piperidines

ChemInform, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Sabine Laschat, Tim Dickner
openaire   +3 more sources

Enantioselective Synthesis of Chiral Piperidines via the Stepwise Dearomatization/Borylation of Pyridines.

Journal of the American Chemical Society, 2016
We have developed a novel approach for the synthesis of enantioenriched 3-boryl-tetrahydropyridines via the Cu(I)-catalyzed regio-, diastereo-, and enantioselective protoborylation of 1,2-dihydropyridines, which were obtained by the partial reduction of ...
K. Kubota, Yuta Watanabe, K. Hayama, Hajime Ito   +3 more
semanticscholar   +1 more source

Diastereoselectively Complementary C-H Functionalization Enables Access to Structurally and Stereochemically Diverse 2,6-Substituted Piperidines.

Organic Letters, 2016
The preparation of 2,6-substituted piperidine derivatives through diastereoselective C-H functionalization of corresponding nitrogen heterocycles represents an appealing protocol and yet remains a formidable challenge.
G. Wang, Ying Mao, Lei Liu
semanticscholar   +1 more source

Conformation-induced regioselective and divergent opening of epoxides by fluoride: facile access to hydroxylated fluoro-piperidines.

Organic and biomolecular chemistry, 2016
Utilizing molecular conformation as a controlling factor, epoxide-containing 2-aryl-piperidines can be ring-opened with the reagent combination of tetrabutylammonium fluoride (TBAF) and potassium bifluoride (KHF2) in a regioselective and divergent ...
Nannan Yan, Z. Fang, Qing-Quan Liu, Xiaohong Guo, Xiangguo Hu   +4 more
semanticscholar   +1 more source

Chiral pyrrolidines and piperidines from enantioselective rhodium-catalyzed cascade arylative cyclization.

Organic Letters, 2015
A new rhodium-catalyzed asymmetric arylative cyclization of nitrogen-tethered alkyne-enoate with arylboronic acids is described. In this process two new carbon-carbon bonds and one stereocenter are formed, providing access to pyrrolidines and piperidines
Fabien Serpier, B. Flamme, J. Brayer, B. Folléas, Sylvain Darses   +4 more
semanticscholar   +1 more source

The chemistry of piperidines—I

Tetrahedron, 1973
Abstract The reaction of pyrrolidine, piperidine and morpholine enamines of 1-methyl-4-piperidone with acraldehyde is found to be a convenient route to 3-aza-3-methyl-6-cycloalkylaminobicyclo[3.3.1]-nonan-9-ones. In each case two difficultly separable ketones are obtained which on reduction give mixtures of isomeric alcohols.
A.Z. Britten, J. O'Sullivan
openaire   +2 more sources

Immobilization of a Photoswitchable Piperidine Base

Organic Letters, 2009
The synthesis of a photoswitchable piperidine base, carrying a monochlorosilane anchoring group, and its immobilization on silica gel, mimicking an oxide surface, is reported. Efficient photoswitching between the E and Z isomers of the azobenzene photochrome was demonstrated for the immobilization precursor in solution and the immobilized piperidine ...
Stefan Hecht, Ragnar S. Stoll
openaire   +3 more sources

Access to Polyfunctionalized Chiral Piperidines through Enantioselective Addition-Carbocyclization Cascade Reaction Catalyzed by a Rhodium(I)-Diene Complex.

Organic Letters, 2015
A new addition-carbocyclization cascade reaction initiated by arylboronic acids and catalyzed by a rhodium/chiral diene complex is described. Starting from N-bridged oxoenoate derivatives, highly functionalized piperidines bearing three contiguous ...
Fabien Serpier, J. Brayer, B. Folléas, Sylvain Darses   +3 more
semanticscholar   +1 more source