Results 301 to 310 of about 40,506 (345)

The Synthesis of Certain Disubstituted Piperidines

Journal of the American Pharmaceutical Association (Scientific ed.), 1951
Several isomers of 2,6-bis-(1-hydroxyalkyl) piperidine hydrochlorides, in which the alkyl group is propyl, butyl, pentyl, hexyl, and benzyl have been prepared by hydrogenating the corresponding five 2,6-diacylpyridine intermediates. 3,5-Diphenylpieridine and a by-roduct, 2,4-diphenylpentamethylenediamine dihydrochlorde, were also prepared.
Glenn L. Jenkins, R.O. Bachmann
openaire   +3 more sources

L-Proline nitrate: a recyclable and green catalyst for the synthesis of highly functionalized piperidines

, 2015
The synthesis of highly functionalized piperidines has been strategically accessed via organo-catalytic three components (in situ five components) reaction of an amine, aldehyde and 1,3-dicarbonyl compound.
N. Agrawal, S. Bahekar, P. Sarode, Sanjio S. Zade, H. Chandak   +4 more
semanticscholar   +1 more source

Stereoselective Rearrangement of (Trifluoromethyl)prolinols to Enantioenriched 3-Substituted 2-(Trifluoromethyl)piperidines.

Organic Letters, 2015
3-Substituted 2-(trifluoromethyl)piperidines B were synthesized by ring expansion of (trifluoromethyl)prolinols A, which were obtained from L-proline via an aziridinium intermediate C.
Sarah Rioton, Aurélie Orliac, Z. Antoun, R. Bidault, Domingo Gomez Pardo, J. Cossy   +5 more
semanticscholar   +1 more source

Ring Contraction of 3-Hydroxy-3-(trifluoromethyl)piperidines: Synthesis of 2-Substituted 2-(Trifluoromethyl)pyrrolidines.

Chemistry, 2015
A ring contraction of 3-hydroxy-3-(trifluoromethyl)piperidines was achieved via an aziridinium intermediate. This contraction facilitates the synthesis of a series of 2-substituted 2-(trifluoromethyl)pyrrolidines incorporating a quaternary center at the ...
Alexandra Feraldi‐Xypolia, Domingo Gomez Pardo, J. Cossy   +2 more
semanticscholar   +1 more source

Enantioselective synthesis of trifluoromethyl substituted piperidines with multiple stereogenic centers via hydrogenation of pyridinium hydrochlorides

, 2015
An enantioselective iridium-catalyzed hydrogenation of trifluoromethyl substituted pyridinium hydrochlorides is described. Introduction of a trifluoromethyl group increases the reactivity due to the electron-withdrawing effect.
Mu-Wang Chen, Zhishi Ye, Zhangpei Chen, Bo Wu, Yong‐Gui Zhou   +4 more
semanticscholar   +1 more source

Pyridine and piperidine alkaloids

1991
The compounds of pyridine and piperidine alkaloids are plant bases and are being isolated from insects and from amphibians and marine animals. They are widely distributed in nature and they perform a number of different functions in nature, such as train pheromones and defense mechanisms in insects. In many cases, the stereochemistry is complex and the
Malcolm Sainsbury, Owen Plunkett
openaire   +2 more sources

Determination of pyrrolidine and piperidine

Analytical Biochemistry, 1964
Conrad G. Honegger, Helen Langemann
openaire   +3 more sources

Piperidine in the cerebellum of the dog

Journal of Neurochemistry, 1970
E Kawahito, Yoshitoshi Kasé, Mikiko Kataoka, Takeshi Miyata   +3 more
openaire   +2 more sources

Biosynthesis of piperidine alkaloids

Tetrahedron Letters, 1968
M.F. Keogh, D. G. O'Donovan
openaire   +3 more sources

1-Benzenesulfinyl Piperidine

2003
[4972-31-0] C11H15NOS (MW 209.31) InChI = 1S/C11H15NOS/c13-14(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1,3-4,7-8H,2,5-6,9-10H2 InChIKey = LBRJCAJLGAXDKP-UHFFFAOYSA-N (reagent used in combination with trifluoromethanesulfonic anhydride to form a powerful electrophilic salt capable of activating thioglycosides and selenoglycosides for ...
openaire   +2 more sources