Results 331 to 340 of about 47,089 (385)

Piperidine nucleosides and nucleotides

Nucleic Acids Symposium Series, 2008
A novel series of racemic piperidin-3-yl and piperidin-4-yl derivatives of nucleobases and their phosphonate derivatives were prepared.
Ivan Rosenberg, Dominik Rejman, Soňa Kovačková, Martin Dračínský, Ondřej Pačes   +4 more
openaire   +3 more sources

Multicomponent synthesis of highly functionalized piperidines

Synthetic Communications, 2020
Highly functionalized piperidines are a versatile class of nitrogen-containing heterocycles which find broad applications in numerous fields such as medicinal chemistry and drug discovery research.
Leili Shaker Ardakani, Arash Arabmarkadeh, M. Kazemi   +2 more
semanticscholar   +1 more source

Bicyclic Piperidines via [2 + 2] Photocycloaddition.

Journal of Organic Chemistry, 2020
A synthetic strategy to fused bicyclic piperidines-building blocks for medicinal chemistry-is developed. The key step was an intramolecular [2 + 2]-photocyclization. The photochemical step was performed on a gram scale.
V. Shcherbakova, Dmitry Dibchak, Mariya Snisarenko, Yevhen Skalenko, Aleksandr V. Denisenko, Anastasiia S. Kuznetsova, Pavel K. Mykhailiuk   +6 more
semanticscholar   +1 more source

Catalytic Access to Bridged Sila- N-heterocycles from Piperidines via Cascade sp3 and sp2 C-Si Bond Formation.

Journal of the American Chemical Society, 2018
Described herein is the development of an unprecedented route to bridged sila- N-heterocycles via B(C6F5)3-catalyzed cascade silylation of N-aryl piperidines with hydrosilanes. Mechanistic studies indicated that an outer-sphere ionic path is operative to
Jianbo Zhang, Sehoon Park, Sukbok Chang
semanticscholar   +1 more source

Highly Diastereoselective Synthesis of Medium-Sized Carbocycle-Fused Piperidines via Sequential Hydride Shift Triggered Double C(sp3)-H Bond Functionalization.

Organic Letters, 2019
Herein we report a diastereoselective synthesis of medium-sized carbocycle-fused piperidines via [1,n (n = 6, 7)]-[1,5]-sequential hydride shift triggered double C(sp3)-H bond functionalization.
Miyabi Kataoka, Yuna Otawa, Natsuki Ido, K. Mori   +3 more
semanticscholar   +1 more source

Transition-Metal-Free Deconstructive Lactamization of Piperidines.

Angewandte Chemie, 2019
One of the major challenges in organic synthesis is the activation or deconstructive functionalization of unreactive C(sp3 )-C(sp3 ) bonds, which requires using transition or precious metal catalysts.
Julio Romero-Ibañez, Silvano Cruz-Gregorio, J. Sandoval-Lira, Julio M Hernández-Pérez, L. Quintero, Fernando Sartillo‐Piscil   +5 more
semanticscholar   +1 more source

ChemInform Abstract: Stereoselective Synthesis of Piperidines

ChemInform, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Sabine Laschat, Tim Dickner
openaire   +3 more sources

2-cyano Δ3 piperidines IV: Spiroannelation in the piperidine series

Tetrahedron Letters, 1981
Abstract The preparation of piperidines 7 and 11 spirosubstituted at C-2 from the 2-cyano Δ3 piperidine 5 is described. The mechanism of their formation is discussed.
H. Harris, H.-P. Husson, David S. Grierson   +2 more
openaire   +2 more sources

Transition-Metal-Free Multiple Functionalization of Piperidines to 4-Substituted and 3,4-Disubstituted 2-Piperidinones.

Chemistry, 2019
Remote and multiple functionalization of piperidines without the use of transition metal catalysts and elaborate directing groups is one of the major challenges in organic synthesis.
Delfino Chamorro‐Arenas, Alejandro A. Nolasco‐Hernández, L. Fuentes, L. Quintero, Fernando Sartillo‐Piscil   +4 more
semanticscholar   +1 more source

The chemistry of piperidines—I

Tetrahedron, 1973
Abstract The reaction of pyrrolidine, piperidine and morpholine enamines of 1-methyl-4-piperidone with acraldehyde is found to be a convenient route to 3-aza-3-methyl-6-cycloalkylaminobicyclo[3.3.1]-nonan-9-ones. In each case two difficultly separable ketones are obtained which on reduction give mixtures of isomeric alcohols.
A.Z. Britten, J. O'Sullivan
openaire   +2 more sources