Advance on delivery nanocarriers of piperine: nanoparticles [PDF]
E3S Web of Conferences, 2019 Piperine is a kind of natural functional active components with spicy flavor and varies pharmacology effects. It has wide application in the food and medicine industries.
Lingli Qin
doaj +2 more sources
Piperine: A comprehensive review of methods of isolation, purification, and biological properties
Medicine in Drug Discovery, 2020 Black pepper is an autoicous and decorous vine cultivated and harvested in tropical regions of Sri Lanka and India. Black pepper is one of the most commonly consumed spices, and its pungency is due to the presence of an alkaloid known as piperine ...
Kakasaheb R Mahadik
exaly +3 more sources
Effect of piperine on the mitigation of obesity associated with gut microbiota alteration
Current Research in Food Science, 2022 An obese mouse model induced by high-fat diet (HFD) feeding was used to reveal the role of piperine in modulating gut microbiota (GM). Piperine was administrated at 20 and 40 mg/kg body weight every day.
Jianlin He, Yufeng Wei
exaly +3 more sources
Piperine inhibits biofilm formation and efflux activity and dysregulates lipid metabolism in Mycobacterium abscessus. [PDF]
PLoS ONEThe nontuberculous Mycobacterium abscessus is a human pathogen that causes chronic lung infections and soft tissue infections. The bacterium forms biofilms and efflux pumps contribute to its tolerance of antibiotics.
Toe Ko Ko Htay +2 more
doaj +2 more sources
Anticancer effect of piperine, a black pepper compound, regulating apoptosis mediated through extracellular vesicles and cathepsin D in acute leukemia [PDF]
Scientific ReportsExtracellular vesicles (EVs) contribute to tumorigenesis in acute leukemia, while natural compounds can counteract these EVs-mediated mechanisms. Piperine, a natural black pepper compound, exerts anticancer activity toward many cancer cells with minimal ...
Kantorn Charoensedtasin +3 more
doaj +2 more sources
Protective effects of piperine on the retina of mice with streptozotocin-induced diabetes by suppressing HIF-1/VEGFA pathway and promoting PEDF expression [PDF]
International Journal of Ophthalmology, 2021 AIM: To evaluate the protective mechanisms of piperine in the retina of mice with streptozotocin-induced diabetes. METHODS: In experiments in vitro, stimulation by chemical hypoxia was established in ARPE-19 cells.
Pu Zhang +3 more
doaj +1 more source
Sustainable Chemistry, 2023 Bioactive compounds like piperine (alkaloids) offer a variety of health benefits due to their biological and pharmacological potential. Piperine has been revealed to have anti-inflammatory, anti-aging, anti-diabetes, anti-bacterial, anti-ulcer, and anti ...
Charles Lwamba +3 more
doaj +1 more source
Synergistic Effects of Piperine and Memantine on Reducing the Symptoms of Depression and BDNF Expression in Corticosterone Model of Depression in Amygdala and Hippocampus of Rat Brain [PDF]
Journal of Mazandaran University of Medical Sciences, 2023 Background and purpose: Depression is a common psychiatric disorder.There are some studies about anti-depressant effect of piperien. This study is about the synergistic effect of piperine and memantine on behavior improvement and BDNF gene expression in ...
Kazem Namazi +7 more
doaj
Aquaculture Reports, 2023 Piperine is a phytobiotic and a polyphenol-derived alkaloid compound extracted from the pepper. We evaluated the effects of dietary piperine on growth, feed utilization, innate immunity, digestibility and disease resistance of Pacific white shrimp ...
Jaebeom Shin +9 more
doaj +1 more source
Indonesian Journal of Pharmacy, 2021 Most of the active pharmaceutical ingredients in the pharmaceutical world are obtained from natural ingredients, one of which is white pepper. White pepper seeds (Piper nigrum L.) contain the main alkaloid compound piperine, which has a broad spectrum ...
Nindya Kusumorini +3 more
doaj +1 more source