Synthesis and Antioxidative Activity of Piperine Derivatives Containing Phenolic Hydroxyl
Journal of Chemistry, 2020 Piperine was used in this study in its raw form, and different steps, such as amide hydrolysis and amidation, were used to synthesize piperine derivatives containing a phenolic hydroxyl group.
Bei Qin, Kuan Yang, Ruijun Cao
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Immunomodulatory Potential of Piperine in Rats
Turkish Journal of ImmunologyObjective: The ultimate goal of this research was to investigate the immunomodulatory potential of piperine, a black pepper alkaloid, on innate and acquired immune responses in Lewis rats.
Alireza Ghavami +2 more
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Piperine Attenuates Pathological Cardiac Fibrosis Via PPAR-γ/AKT Pathways
EBioMedicine, 2017 Mitogen-activated protein kinases (MAPKs) and AMPactivated protein kinase α (AMPKα) play critical roles in the process of cardiac hypertrophy.
Zhen-Guo Ma +5 more
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A rapid HPTLC method to estimate piperine in Ayurvedic formulations
Journal of Ayurveda and Integrative Medicine, 2019 Background: Trikatu, Sitopaladi, Hingavastaka, Avipattikara, Sringyadi and Talisadya are very popular Ayurvedic (churna) medicines practiced in India; however, unfortunately, they possess several quality control issues.
Alok K. Hazra +3 more
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Piperine as a phytogenic additive in broiler diets
Pesquisa Agropecuária Brasileira, 2012 The objective of this work was to determine the effect of piperine as a phytogenic additive in chicken broiler diet. Seven‑day‑old male chicks were randomly allocated in four experimental treatments (n = 24), with four replicates (n = 6).
Verônica da Silva Cardoso +4 more
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Cancer Chemoprevention and Piperine: Molecular Mechanisms and Therapeutic Opportunities
Frontiers in Cell and Developmental Biology, 2018 Cancer is a genetic disease characterized by unregulated growth and dissemination of malignantly transformed neoplastic cells. The process of cancer development goes through several stages of biochemical and genetic alterations in a target cell.
Rafiq A. Rather, Madhulika Bhagat
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Ethanol Extract of Piper longum L., a Culinary Spice, Suppresses Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss. [PDF]
J Food SciABSTRACT Piper longum L., commonly consumed as a culinary spice and referred to as Piperis Fructus (PF) in traditional East Asian medicine, has been associated with various pharmacological activities; however, the anti‐osteoporotic potential of its ethanol extract has not been fully elucidated.
Moon JH +7 more
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Synthesis and Characterisation of Piperine-loaded Starch Nanoparticles [PDF]
, 2020 This study aimed to explore the potential application of starch nanoparticles as the nanocarriers for the controlled release of piperine. Starch nanoparticles with mean particle sizes ranging from 50 nm to 200 nm have been synthesised as nanocarriers for
Chin, Suk Fun +3 more
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Piperine causes G1 phase cell cycle arrest and apoptosis in melanoma cells through checkpoint kinase-1 activation. [PDF]
PLoS ONE, 2014 In this study, we determined the cytotoxic effects of piperine, a major constituent of black and long pepper in melanoma cells. Piperine treatment inhibited the growth of SK MEL 28 and B16 F0 cells in a dose and time-dependent manner.
Neel M Fofaria +2 more
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Piperine-Loaded PLGA Nanoparticles as Cancer Drug Carriers
, 2021 Factors like oxidative stress, environmental risk factors, genetics, chemical treatments, and resistance to treatment strategies all have serious impediments in scientific progress for treating diseases.
Amit Kumar +9 more
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