Results 41 to 50 of about 596,846 (253)
PLoS ONE, 2011 The piriform cortex receives input from the olfactory bulb and (via the entorhinal cortex) sends efferents to the hippocampus, thereby connecting the two canonical neurogenic regions of the adult rodent brain.
Friederike Klempin +4 more
doaj +1 more source
Olfactory function in focal epilepsies: Understanding mesial temporal lobe epilepsy beyond the hippocampus [PDF]
, 2019 Several lines of research have linked olfactory regions with the pathophysiology of focal epilepsies. Among those regions, the piriform cortex represents the major part of the primary olfactory cortex.
Aledo Serrano, Angel +6 more
core +2 more sources
Nonsensory target-dependent organization of piriform cortex [PDF]
Proceedings of the National Academy of Sciences, 2014 Significance The mammalian olfactory system is capable of detecting and discriminating a vast and diverse array of small organic molecules or odorants. Complex blends of these chemicals are finally perceived as a unified odor object—for example, a rose contains dozens of active compounds.
Chien-Fu F, Chen +5 more
openaire +2 more sources
NeuroImage, 2021 Olfaction could prove to be an early marker of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. To use olfaction for disease diagnosis, elucidating the standard olfactory functions in healthy humans is necessary.
Yuka Donoshita +3 more
doaj +1 more source
Early Gabapentin Treatment during the Latency Period Increases Convulsive Threshold, Reduces Microglial Activation and Macrophage Infiltration in the Lithium-Pilocarpine Model of Epilepsy [PDF]
, 2017 The lithium-pilocarpine model of epilepsy reproduces several features of temporal lobe epilepsy in humans, including the chronological timeline of an initial latency period followed by the development of spontaneous seizures. Epilepsy therapies in humans
Auzmendi, Jerónimo Andrés +3 more
core +3 more sources
PLoS ONE, 2011 BackgroundSleep plays an active role in memory consolidation. Sleep structure (REM/Slow wave activity [SWS]) can be modified after learning, and in some cortical circuits, sleep is associated with replay of the learned experience.
Dylan C Barnes +3 more
doaj +1 more source
TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy [PDF]
, 2017 Significance Alzheimer’s disease (AD) is the most common cause of dementia and is a major public health problem for which there is currently no disease-modifying treatment.
Anderson, Elise +9 more
core +2 more sources
Circuit-specific dendritic development in the piriform cortex [PDF]
eneuro, 2019 AbstractDendritic geometry is largely determined during postnatal development and has a substantial impact on neural function. In sensory processing, postnatal development of the dendritic tree is affected by two dominant circuit motifs, ascending sensory feedforward inputs and descending and local recurrent connections.
Laura Moreno-Velasquez +7 more
openaire +4 more sources
JAMA Neurology, 2019 Importance A functional area associated with the piriform cortex, termed area tempestas, has been implicated in animal studies as having a crucial role in modulating seizures, but similar evidence is limited in humans.
M. Galovic +32 more
semanticscholar +1 more source
Odor identity coding by distributed ensembles of neurons in the mouse olfactory cortex
eLife, 2017 Olfactory perception and behaviors critically depend on the ability to identify an odor across a wide range of concentrations. Here, we use calcium imaging to determine how odor identity is encoded in olfactory cortex.
Benjamin Roland +4 more
doaj +1 more source