Results 51 to 60 of about 17,674 (187)

Laparoscopic stapled partial cystectomy with intraoperative cystourethroscopy for urothelial carcinoma in two dogs

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To describe the procedure and short‐term outcomes of two dogs that underwent laparoscopic stapled partial cystectomy with intraoperative cystoscopy for excision of solitary, non‐trigonal, urothelial carcinoma lesions. Animals A 12‐year‐old female spayed mixed breed and a 13‐year‐old female spayed Siberian Husky.
Maureen A. Griffin   +2 more
wiley   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi   +6 more
wiley   +1 more source

Effects of various penetration enhancers on percutaneous absorption of piroxicam from emulgels [PDF]

open access: yes, 2012
A suitable emulgel formulation of piroxicam was prepared and its percutaneous permeation was investigated using Wistar rat skin and diffusion cell technique.
Azarmi, Sh   +5 more
core   +2 more sources

A Pilot Double-Blinded, Randomized, Clinical Trial of Topical Virgin Olive Oil Versus Piroxicam Gel in Osteoarthritis of the Knee [PDF]

open access: yes
Osteoarthritis (OA) is the most common type of arthritis, and the knee is the most common site of symptomatic OA.1 Knee OA is responsible for a higher incidence of disability than any other long-term conditions.2 Topical therapies present a therapeutic ...
بقایی, زهرا   +4 more
core   +1 more source

Prediction of the permeability of neutral drugs inferred from their solvation properties [PDF]

open access: yes, 2015
Determination of drug absorption is an important component of the drug discovery and development process in that it plays a key role in the decision to promote drug candidates to clinical trials.
Milanetti, Edoardo   +2 more
core   +1 more source

Complete Response to the Combination of Immunotherapy and Targeted Therapy in Stage IV Nasal Adenocarcinoma of a Dog: A Case Report

open access: yesVeterinary Medicine and Science, Volume 12, Issue 2, March 2026.
The combination therapy of anti‐PD‐1 and TOC showed good therapeutic effects in this case of canine nasal adenocarcinoma, underscoring the potential of combining immunotherapy with targeted therapy in cases where single‐agent treatments fail. Combination therapy may enhance tumour growth inhibition by regulating the tumour immune microenvironment.
Yi Hu   +6 more
wiley   +1 more source

Histological changes induced by Piroxicam on the hepatic and renal tissues of mice with and without administration of Peppermint oil

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2022
Piroxicam is a popular anti-inflammatory drug that displays palliative and antipyretic activity. Peppermint oil is a common flavoring used in foods and drinks.
Al-Hamdany Muna   +2 more
doaj   +1 more source

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Are Associated with a High Incidence of Gastrointestinal Side-Effects [PDF]

open access: yes, 2013
Inhibition of the cyclooxygenase  (COX) enzyme is the basis for both the efficacy and toxicity of NSAIDs. The aim of this study was to avaluate the non-steroidal anti-inflammatory drugs were used in neuro polyclinic hospital of Dr.
Azizah, L. (Lailan)
core   +2 more sources

Serum Symmetric Dimethylarginine as a Predictor of Toxicity of Carboplatin in Dogs

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 1, Page 140-149, March 2026.
ABSTRACT Glomerular filtration rate (GFR) predicts carboplatin clearance and myelotoxicity in humans and cats. This relationship is unknown in dogs. In canines, elevated serum symmetric dimethylarginine (SDMA) correlates with reduced GFR. This study prospectively evaluated whether dogs with elevated SDMA (> 14 μg/dL) are at increased risk of ...
Alexandra Gareau   +3 more
wiley   +1 more source

Early tumor response to intraarterial or intravenous administration of carboplatin to treat naturally occurring lower urinary tract carcinoma in dogs. [PDF]

open access: yes, 2015
BackgroundSurvival times and tumor responses associated with malignant neoplasia of the lower urinary tract are poor despite the vast array of current treatments.
Berent, AC   +8 more
core  

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