Results 61 to 70 of about 9,407 (166)
ABSTRACT A series of novel chiral urea and thiourea compounds were designed as multitarget‐directed ligands for Alzheimer's disease and evaluated against hAChE, hBChE, and hMAO‐B, with exploratory assessment of HSD10. These chiral compounds were synthesized and fully characterized, and their enantiopurity was confirmed via HPLC.
Sule Erol Gunal +10 more
wiley +1 more source
Fotossensibilidade induzida pelo piroxicam.
In Portugal, piroxicam is one of the most prescribed non-steroidal anti-inflammatory agents (NSAIDs) and is frequently associated to photosensitivity skin reactions, well known by all dermatologists.
P Varela +4 more
doaj +1 more source
Fluorinated aminopiperidones, designed as non‐glutarimide thalidomide analogs, were synthesized with full regio‐ and stereocontrol. The C*–CF3 used as carbonyl surrogate improved solubility and membrane interactions while abolishing cereblon binding.
Boštjan Adamlje +11 more
wiley +1 more source
STABILITAS FISIKA DAN KIMIA REKRISTAL DAN DISPERSI PADAT PIROKSIKAM-PEG 6000
It is hoped that solid dispersion and recrystalization can solve the problem of low solubility of piroxicam. Metastable polymorph or amorph state can be formed in solid dispersion and recrystalization preparation, leading to a better dissolution. During
Annas Binarjo
doaj +1 more source
Coordination chemistry offers a versatile platform where noncovalent interactions play a critical role in driving the formation of self‐assemblies and supramolecular structures. This account chronicles our research trajectory, guided by the fundamental investigations into the structures and properties of transition metal complexes, toward the ...
Vonika Ka‐Man Au
wiley +1 more source
Adverse Reactions of Piroxicam
During the approximately five years (1981–86) that piroxicam has been available in South Africa, the Medicines Safety Centre has received 31 reports of adverse reactions associated with this drug.
Dewald Gerber, P. F. D'Arcy
core +1 more source
Interaction of piroxicam with mitochondrial membrane and cytochrome c [PDF]
Modulation of surface properties of biomembranes by any ligand leading to permeabilization, fusion, rupture, etc. is a fundamental requirement for many biological processes.
Chakraborty, Hirak +4 more
core +1 more source
Melatonin protects against piroxicam-induced gastric ulceration
The antiulcer e.ect of melatonin on gastric lesions caused by piroxicam was studied with the intent of determining the mechanism of action of this agent.
Russel J. Reiter +7 more
core +1 more source
Khaya senegalensis inhibits piroxicam mediated gastro-toxicity in wistar rats [PDF]
Objective:The purpose of this study was to investigate the effects of piroxicam co-administration with ethanolic stem-bark extract of Khaya senegalensis on biomarkers of oxidative stress and gastro-toxicity in Wistar rats.
Fatima Nnawodu Ishaq +2 more
doaj
Effective method for the detection of piroxicam in human plasma using HPLC
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used by the general population to alleviate inflammation and pain after oral surgeries. Piroxicam is among the most commonly used NSAIDs and excels in controlling pain, swelling, trismus and other
Adriana Maria CALVO +7 more
doaj +1 more source

