Results 51 to 60 of about 17,813 (206)

The Development of Transdermal Piroxicam Using HPMC Matrices With PVP K-30 as a Penetration Enhancer [PDF]

, 2006
The physicochemical properties such as solubility, partition coefficient, and membrane permeability of a drug are required for formulating and estimating drugs absorption that pass through biological membranes.
Aryani, Ni Luh Dewi
core  

Codocytosis in the Dog: 345 Cases (2020–2022)

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Introduction Codocytes, or target cells, are a morphologic variation of erythrocytes characterized by increased membrane surface area relative to volume. In dogs, codocytosis is frequently noted on blood smear evaluation, but its clinical significance remains poorly understood. Objectives To characterize the clinical conditions associated with
Sarena M. Krojanker, Maria Jaramillo, Brad D. Cingolani, Floyd L. Williams Jr., Priscila B. S. Serpa, Andrew D. Woolcock   +5 more
wiley   +1 more source

TOPICAL OLEO-HYDROGEL PREPARATIONS OF PIROXICAM WITH ENHANCED SKIN PERMEABILITY AND ANTIINFLAMMATORY ACTIVITY

Zagazig Journal of Pharmaceutical Sciences, 2000
In an attempt to improve the skin permeation and anti-inflammatory activity of piroxicam, various topical formulations including oleo-hydrogels (oleo-gels) were prepared and their in vitro diffusion, skin permeation and in vivo anti-inflammatory ...
Fergany Mohammed , Nailia Boulatova
doaj   +1 more source

Dermatological Adverse Events Associated With Lapatinib Treatment in Dogs With Urothelial Carcinoma: A Retrospective Study

Veterinary Dermatology, EarlyView.
Lapatinib is widely used in human oncology; however, dermatological adverse events (DAEs) are common and have been correlated with treatment efficacy. In veterinary medicine, lapatinib use in combination with piroxicam has been shown to be effective in treating canine urothelial carcinoma (UC); however, the incidence and prognostic significance of DAEs
Kosuke Horita, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda   +3 more
wiley   +1 more source

Photocatalyzed Ring Expansion of α‐Ketosulfonylaziridines: Ready Access to δ‐Sultams

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
A novel radical–polar crossover (RPC) photoredox‐catalyzed reaction for the synthesis of δ‐sultams from N‐sulfonyl α‐ketoaziridines through a controlled ring opening–expansion process is presented. This method allows the easy access to sultams with an unprecedented substitution pattern in up to 85% yield and 2:1 d.r., and highlights the potential of ...
Marco M. Mastandrea, Stefania Perulli, Vittoria Martini, Ludovica Primitivo, Lei‐Jie Zhou, Christian Mück‐Lichtenfeld, Miquel A. Pericàs, Olga García Mancheño   +7 more
wiley   +2 more sources

Actionable Pharmacogenomics and Essential Medicines: An Analysis of WHO and African Lists for Safer and Efficacious Drug Use

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1371-1381, May 2026.
The World Health Organization Model Essential Medicines List and African national essential medicines lists (EMLs) detail drugs intended to be consistently available within national health systems, thereby supporting clinicians and pharmacists in making evidence‐based treatment decisions.
Tinashe A. Mazhindu, Mohamed Nagy, David Twesigomwe, Gaye Agesa, Janine Scholefield, Collen Masimirembwa   +5 more
wiley   +1 more source

Laparoscopic stapled partial cystectomy with intraoperative cystourethroscopy for urothelial carcinoma in two dogs

Veterinary Surgery, Volume 55, Issue 4, Page 856-863, May 2026.
Abstract Objective To describe the procedure and short‐term outcomes of two dogs that underwent laparoscopic stapled partial cystectomy with intraoperative cystoscopy for excision of solitary, non‐trigonal, urothelial carcinoma lesions. Animals A 12‐year‐old female spayed mixed breed and a 13‐year‐old female spayed Siberian Husky.
Maureen A. Griffin, Christian Folk, Nicole J. Buote   +2 more
wiley   +1 more source

Piroxicam and intracavitary platinum-based chemotherapy for the treatment of advanced mesothelioma in pets: preliminary observations [PDF]

, 2008
Malignant Mesothelioma is an uncommon and very aggressive tumor that accounts for 1% of all the deaths secondary to malignancy in humans. Interestingly, this neoplasm has been occasionally described in companion animals as well. Aim of this study was the
Enrico P Spugnini, Stefania Crispi, Alessandra Scarabello, Giovanni Caruso, Gennaro Citro, Alfonso Baldi, BWS Robinson, J Peto, BT Mossman, EP Spugnini, EP Spugnini, M Carbone, A De Luca, JJ Manfredi, S Tomek, D Curran, AP Chahinian, MK Samson, SC White, A Hughes, HL Kindler, EP Spugnini, KW Head, CP Raflo, K Akiyama, B Bacci, Y Kobayashi, M Rinke, Y Suzuki, A Sparkes, AS Moore, KK Kerstetter, J Jackson, GK Ogilvie, GK Ogilvie, RL Stepien, LA Gallagher, SJ Birchard, A Porrello   +38 more
core   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Phosphorylation of silk fibroins improves the cytocompatibility of silk fibroin derived materials: a platform for the production of tuneable material [PDF]

, 2014
Silk fibroin demonstrates great biocompatibility and is suitable for many biomedical applications, including tissue engineering and regenerative medicine.
Adams, Ann H. Cory, Bramson, Bruylants, Budhavaram, Chiao, Costa, D'Angelo, Dawson, Freddi, Fuller, Ganguly, Geladopoulos, Ha, Hezi-Yamit, Higuchi, Hofmann, Hu, Huang, Kamlesh, Kaplan, Karageorgiou, Khorasani, Khorasani, Kiremitçi, Kong, Kreegipuu, Li, Liu, Liu, Magoshi, Magoshi, Mai-ngam, Mandell, Mann, Mieszawska, Mo, Modhave, Motomizu, Motta, N. V. Bhat, Numata, Numata, O'Toole, Philip, Polyansky, Poskus, Potoyan, Richards, Rothstein, Shang, Shen, Silva, Silva, Skehan, Smiechowski, Tabata, Takács-Novák1, Tanaka, Tsukada, Vepari, Wang, Wang, Westheimer, Winkler, Winkler, Wong Po Foo, Xue, Xue, Yang, Zhou   +70 more
core   +1 more source