Results 71 to 80 of about 957,581 (316)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Examination of certain technological procedures during the alcoholic fermentation of plum wine [PDF]
The purpose of this paper is to examine the effect of certain technological parameters of alcoholic fermentation on the quality of plum wines produced. As part of this research, the application of various commercial pectolytic enzymes to the treatment of
Miljić Uroš D. +3 more
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Lajikkeen ja lannoitustavan vaikutus kevätvehnän viljelyarvoon
Tutkimuksessa on monitekijäkokein selvitelty kolmen kevätvehnälajikkeen (Apu, Ruso ja Svenno) viljelyarvoa eri lannoitustasoilla (0, 400 ja 800 kg/ha Yn) sekä lannoitteiden hajalevitystä että rivimultausta käyttäen.
Erkki I. Kivi, Simo Hovinen
doaj
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani +7 more
wiley +1 more source
Maria Sember, Chad Donley, Matthew Eggleston Department of Emergency Medicine, Mercy Health Youngstown Hospital, Youngstown, OH, USACorrespondence: Chad DonleyDepartment of Emergency Medicine, Mercy Health Youngstown Hospital, 1044 Belmont Avenue ...
Sember M, Donley C, Eggleston M
doaj
Mycotoxin occurrence on baled and pit silages collected in Co. Meath
Recent studies of baled silages produced in Ireland have identified considerable filamentous fungal contamination. Many of these fungi are toxigenic, capable of producing secondary metabolites, namely mycotoxins. Mycotoxins are potentially detrimental to
McElhinney C. +3 more
doaj +1 more source
Progress on Polynomial Identity Testing - II [PDF]
We survey the area of algebraic complexity theory; with the focus being on the problem of polynomial identity testing (PIT). We discuss the key ideas that have gone into the results of the last few years.Comment: 17 pages, 1 figure ...
Saxena, Nitin
core +2 more sources
PIT: a practical mutation testing tool for Java (demo)
Mutation testing introduces artificial defects to measure the adequacy of testing. In case candidate tests can distinguish the behaviour of mutants from that of the original program, they are considered of good quality -- otherwise developers need to ...
Henry Coles +4 more
semanticscholar +1 more source
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source

