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Sleep MedicineBackground: Narcolepsy is a chronic sleep disorder characterized mainly by excessive daytime sleepiness (EDS) and cataplexy in the case of narcolepsy type 1 (NT1).
Svenja Happe, Isabelle Lecomte
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Quantification of Pitolisant: A RP - HPLC study
YMER Digital, 2022Objective An attempt was made to develop a simple, isocratic and robust reverse phase high performance liquid chromatographic method for Pitolisant. Material and methods An Inertsil octa decyl silane column and photo diode array detector were employed for the quantification of Pitolisant at 268 nm using a mobile phase consisting of acetonitrile and 0.1
Sowjanya Gummadi +1 more
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Antihistamine agents and pitolisant might be useful for anorexia nervosa
Medical Hypotheses, 2019This hypothesis is that patients with anorexia nervosa (AN) demonstrate derangement in the histamine central nervous system. It might be possible to ameliorate these by careful use of histamine receptor antagonists targeting Histamine 1, 2, or 3 receptors. Histamine 3 receptors are exclusively present in the brain.
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