Results 121 to 130 of about 627,391 (362)
Animal Research and One Health, EarlyView.This study was to evaluate the role of GH in lipolysis and insulin sensitivity in bovine adipocytes and clarify the underlying mechanism. Our findings demonstrate that GH activates ERK/HSL signaling pathway, promotes lipolysis, and impairs insulin sensitivity in bovine adipocytes.
Xinxing Gao +10 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims There is a potential risk of systemic side‐effects with the use of potent corticosteroids, such as clobetasol propionate (CP). This concern is of particular interest in paediatric patients. The aim of this study was to develop and verify a physiologically based pharmacokinetic (PBPK) model to describe the local and systemic exposure to CP
Janna K. Duong +6 more
wiley +1 more source
Residual Tumor Confers a 10-Fold Increased Risk of Regrowth in Clinically Nonfunctioning Pituitary Tumors. [PDF]
, 2019 ObjectiveWe evaluated tumor recurrence and regrowth rates following endoscopic transnasal transsphenoidal (TNTS) surgical removal in a consecutive series of clinically nonfunctioning pituitary adenomas (CNFTs).DesignRetrospective chart review of clinical,
Bergsneider, Marvin +10 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Glucagon‐like peptide‐1 (GLP‐1) and glucagon dual receptor agonists are in clinical development for a range of metabolic conditions, including type 2 diabetes and obesity. The cardiovascular actions at these receptors are well studied, but less is known about their combination.
James Goodman +13 more
wiley +1 more source
Fusion Pores as Regulators of Quantal Size and Cellular Physiology
BioEssays, EarlyView.During regulated exocytosis, membrane fusion regulatory factors act directly on SNAREs and membrane lipids to control fusion pore dynamics. This, in turn, leads to a differential amount of cargo release (referred to in this article as “quantal size”) across various cell types, thereby triggering distinct physiological cues.
Bhavya R. Bhaskar +3 more
wiley +1 more source
BioEssays, EarlyView.Regarding pituitary gonadotropin regulation, recent studies have shown that in mammals, FSH and LH are regulated by a single GnRH (solo GnRH model), whereas in teleosts, they are regulated by CCK (FSH‐RH) and GnRH (LH‐RH), respectively (dual GnRH model).
Daichi Kayo +3 more
wiley +1 more source
Benign Lymphogranuloma of Schaumann with Apparent Involvement of the Anterior Pituitary [PDF]
, 1945 H. W. Barber
openalex +1 more source
Under‐Interpretation of Neuroimaging Data in Insanity Assessment: A Hidden Risk
Behavioral Sciences &the Law, EarlyView.ABSTRACT Neuroimaging data can provide valuable insights into insanity evaluations, but the debate over its use for legal purposes is far from resolved. While much attention has been given to the risks of over‐interpretation, potential errors stemming from under‐interpretation received less scrutiny. In this paper, we aim to showcase how this error may
Camilla Frangi +5 more
wiley +1 more source