Results 111 to 120 of about 416,939 (310)

Identifying research priorities for pituitary adenoma surgery: an international Delphi consensus statement [PDF]

Purpose Pituitary surgery is the mainstay treatment for most pituitary adenomas, but many questions remain about perioperative and long-term management and outcomes.
Kolias, AG, Baldeweg, Stephanie E., Geltzeiler, Mathew, Fleseriu, Maria, Koulouri, Olympia, Serrano, I, Drake, William M., Fernandez-Miranda, JC, Fleseriu, M, Gurnell, M, Valetopoulou, A, Melmed, S, Schwartz, Theodore H., Borg, A, Baldeweg, SE, Melmed, Shlomo, Borg, Anouk, Bremner, Fion, Layard Horsfall, H, Buchfelder, Michael, Schwartz, TH, Ginn, J, Kolias, Angelos G., Santarius, T, McBride, Pat, Zada, Gabriel, Dorward, N, Khan, Danyal Z., Bouloux, PMG, Koulouri, O, Miszkiel, KA, Raverot, G, Gurnell, Mark, Newall, Nicola, Kosmin, Michael, Jaunmuktane, Zane, Drake, WM, Buchfelder, M, Harris, Steve, McCormack, AI, Newall, N, McCormack, Ann I., Mamelak, Adam N., Ginn, Joy, Korbonits, Márta, Bremner, F, PitCop Collaborative, Cudlip, Simon, Raverot, Gerald, Geltzeiler, M, Fernandez-Miranda, Juan C., Bouloux, Pierre M. G., Marcus, Hani J., Khan, DZ, Mamelak, AN, Marcus, HJ, Harris, S, Kosmin, M, Santarius, Thomas, Mannion, R, Mannion, Richard, Serrano, Inma, McBride, P, Zada, G, Miszkiel, Katherine A., Valetopoulou, Alexandra, Korbonits, M, Cudlip, S, Layard Horsfall, Hugo, Jaunmuktane, Z, Dorward, Neil   +70 more
core   +1 more source

Microbial‐Metabolite Signatures Are Associated With Glucocorticoid Responsiveness in Chronic Rhinosinusitis With Nasal Polyps

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang, Xin‐Yu Ding, Mei‐Ping Lu, Yan‐Bing Chen, Ye Yuan, Lin Jiang, Min Zhang, Lei Cheng   +7 more
wiley   +1 more source

Clinicopathological significance of baseline T2-weighted signal intensity in functional pituitary adenomas

, 2018
Purpose To assess baseline T2-weighted signal intensity (T2-WSI) of functional pituitary adenomas (FPA), and to investigate the relationship of baseline T2-WSI with clinical features, histopathological granulation patterns, and response to treatment in ...
Bilgic, Bilge, Tanrikulu, Seher, Sakin Tekin, Dogansen, Sema Ciftci, Yarman, Sema, Sema Yarman, Yalin, Gulsah Yenidunya, Gulsah Yenidunya Yalin, Bilge Bilgic, Sema Ciftci Dogansen, Sencer, Serra, Nihan Nizam, Tekin, Sakin, Serra Sencer, Nizam, Nihan, Seher Tanrikulu   +15 more
core   +1 more source

Poly(I:C)‐Activated Nasal Fibroblasts Promote Eosinophil Recruitment in CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by persistent mucosal inflammation and eosinophilic infiltration. Although epithelial and immune cells have been widely studied, the role of nasal fibroblasts in innate immune activation and eosinophil recruitment remains unclear.
Chaewon Shin, An‐Gi Kim, Byeong Min Yu, Woo‐Keun Kwon, Min‐Ho Hwang, Joo‐Hoo Park   +5 more
wiley   +1 more source

Effects of physical training on serum and pituitary growth hormone contents in diabetic rats

, 2009
The present study investigated the effects of moderate physical training on some of the parameters in the GH-IGF axis in experimental diabetic rats. Male Wistar rats were allocated into the following groups: sedentary control, trained control, sedentary ...
de Moura, Rodrigo Ferreira, Rogatto, Gustavo Puggina, de Araujo, Michel Barbosa, Luciano, Eliete, de Moura, Leandro Pereira, Curiacos de Almeida Leme, Jose Alexandre, Gomes, Ricardo Jose, Rostom de Mello, Maria Alice   +7 more
core   +1 more source

Assessing the Mucosal Inflammatory Endotype of Obesity in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory syndrome of the paranasal sinuses that is defined phenotypically as either with nasal polyps (CRSwNP) or without nasal polyps (CRSsNP). More recently, inflammatory markers have been used to cluster patients into putative endotypes that are presumed to have a common ...
Jeffanie W. Gayoso, Li‐Ching Huang, Quanhu Sheng, Daniel Lofgren, Ping Li, Katherine Cahill, Mason Krysinski, Rakesh K. Chandra, Justin H. Turner, Naweed Chowdhury   +9 more
wiley   +1 more source

Additional file 6: of Distribution of ncRNAs expression across hypothalamic-pituitary-gonadal axis in Capra hircus

, 2018
Pathways identified for (experimentally observed) genes targeted by upregulated miRNA expressed in the pituitary, hypothalamus and ovary.
Paolo Marsan (3563915), Andrea Talenti (4171039), John Williams (32544), Bianca Castiglioni (4171036), Paola Crepaldi (517054), Stefania Chessa (4171051), Giulio Pagnacco (3228531), Emanuele Capra (4171048), Beatrice Coizet (3261549), Alessandra Stella (28791), Barbara Lazzari (28788), Stefano Frattini (3261540)   +11 more
core   +1 more source

Baihe Zhimu Decoction ameliorates anxious depression via PI3K/AKT/mTOR pathway‐mediated neuroprotection and inhibition of hippocampal neuronal apoptosis

Animal Models and Experimental Medicine, EarlyView.
Baihe Zhimu Decoction alleviates anxious depression‐like behaviors and protects hippocampal neurons. Chemical profiling and network pharmacology reveal multiple active components acting via the PI3K/AKT/mTOR pathway, enhancing neuronal survival and function, as confirmed by multi‐level in vitro and in vivo validation.
Yuanshan Han, Kexin He, Haolan Yang, Jiacheng Dai, Ronglin Chen, Yang Liu, Yuhong Wang, Lin Tang, Hongqing Zhao   +8 more
wiley   +1 more source

Extracapsular en bloc resection in pituitary adenoma surgery

, 2015
PURPOSE: A pituitary pseudocapsule often contains tumor tissue and should be removed for radical resection. It can be used as a surgical plane for more radical resection of the tumor in many cases of pituitary adenomas.
이은직, 구철룡, 김의현, 김선호   +3 more
core   +1 more source

Much more than their fangs: Macroscopic anatomy of the brain of Bothrops moojeni Hoge 1966 (Squamata, Serpentes, Viperidae)

The Anatomical Record, EarlyView.
Abstract Neuroanatomical research has progressed considerably in several vertebrate lineages, yet studies of reptilian brain morphology remain markedly underdeveloped. Here we provide the first description of macroscopic brain anatomy and its ontogeny in the viperid Bothrops moojeni, based on a sample of seven individuals.
Paula Araújo, Júlio César Costa de Souza, Angele Martins   +2 more
wiley   +1 more source