Results 91 to 100 of about 416,939 (310)

Management of Intracranial Perforator Aneurysms

Stroke: Vascular and Interventional Neurology
Intracranial perforator aneurysms are rare but potentially life‐threatening vascular lesions that can lead to subarachnoid hemorrhage. Initial imaging is frequently negative, so a high level of suspicion is important for efficient detection of perforator
Karthik Papisetty, Sam J. Schulz, Rajiv Dharnipragada, Andrew S. Venteicher   +3 more
doaj   +1 more source

Associations between early life stress and anterior pituitary gland volume development – A novel index of long-term hypothalamic-pituitary-adrenal axis functioning

, 2021
Associations between early life stress and anterior pituitary gland volume development – A novel index of long-term hypothalamic-pituitary-adrenal axis ...
Jee Hyun Kim (13075509), P Farrow (13478482), S Whittle (13363980), JG Simmons (14462010), C Díaz-Arteche (13478479), O Schwartz (13478263), DE Ganella (14876710)   +6 more
core  

ViTAMIn‐O: Democratizing Computer Vision‐Based Machine Learning for Stem Cell Research

Advanced Intelligent Systems, EarlyView.
This study introduces a fully open generalist computer vision model for predicting the differentiation outcomes of stem cell‐based model systems, together with its code‐free deployment platform, ColabViTAMIn‐O. It is benchmarked against various architectures, datasets, and training protocols.
Ferhat Hamurcu, Markus Breunig, Arpad Varga, Bianka Bosch, Jessica Lindenmayer, Anjan T. Kanakappady, Kevin Achberger, Natalia Pashkovskaia, Alexander Kleger, Stefan Liebau, Stefanie Klingenstein, Moritz Klingenstein   +11 more
wiley   +1 more source

Recurrent Cushing’s disease due to postoperative seeding of tumor cells in the sphenoid sinus: a case report with review of the literature

Endocrine Journal
Recurrent Cushing’s disease is most commonly caused by residual or newly developed pituitary neuroendocrine tumor (PitNET) tissue within the sellar region. Extrasellar recurrence due to postoperative tumor cell seeding is exceedingly rare.
Tatsuma Matsuda, Noriaki Fukuhara, Masahiko Tosaka, Kentaro Horiguchi, Yoshinori Higuchi, Hiroshi Nishioka   +5 more
doaj   +1 more source

Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders [PDF]

, 2001
The homeobox gene Hesx1/HESX1 has been implicated in the establishment of anterior pattern in the central nervous system (CNS) in a number of vertebrate species.
Tyrell, R, Warner, J., Beddington, R.S., Stewart, A., Woods, K, McNay, D, Stewart, A, Warner, J, Beddington, RSP, Dattani, M, Brickman, J.M., Tyrell, R., Brickman, JM, Clements, M, Woods, K., Clements, M., McNay, D., Dattani, M.   +17 more
core  

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

The hypothalamic-pituitary-adrenal axis in critical illness [PDF]

, 1993
Plasma ACTH and cortisol concentrations are frequently elevated in patients in intensive care units (ICU). To examine the functional integrity of the hypothalamic-pituitary-adrenal axis during critical illness, we evaluated prospectively 53 ICU patients ...
Winkelmann, W., Allolio, B., Würth, G., Reincke, Martin   +3 more
core   +1 more source

3D Facial Analysis in Acromegaly: Gender-Specific Features and Clinical Correlations

Frontiers in Endocrinology, 2018
Objective: Quantitative investigations of facial changes in acromegaly are rare. A new imaging technique, three-dimensional (3D) stereophotography, can accurately quantify whole facial changes.
Xiaopeng Guo, Xiaopeng Guo, Xiaopeng Guo, Tian Meng, Jiuzuo Huang, Xiaojun Wang, Wei Lian, Wei Lian, Wei Lian, Kan Deng, Kan Deng, Kan Deng, Lu Gao, Lu Gao, Lu Gao, Zihao Wang, Zihao Wang, Zihao Wang, Bing Xing, Bing Xing, Bing Xing, Xiao Long   +21 more
doaj   +1 more source

COX14 Variants Are Associated With Mitochondrial Complex IV Deficiency Nuclear Type 10 (MC4DN10)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT COX14 encodes a transmembrane protein essential for cytochrome c oxidase (COX) complex assembly. A homozygous missense variant in COX14 was reported in three siblings from a single consanguineous family with severe, fatal infantile mitochondrial complex IV deficiency nuclear type 10 (MC4DN10; MIM# 619053).
Elias K. Awad, Emily Waskow, Hari Tunuguntla, Joseph Spinner, Hanna J. Tadros, Lisa T. Emrick, Daniel G. Calame, Fernando Scaglia   +7 more
wiley   +1 more source

Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling

Cell Communication and Signaling, 2017
Background Meningiomas are the most common primary intracranial tumors in adults. While a majority of meningiomas are slow growing neoplasms that may cured by surgical resection, a subset demonstrates more aggressive behavior and insidiously recurs ...
Yu Mei, Ziming Du, Changchen Hu, Noah F. Greenwald, Malak Abedalthagafi, Nathalie Y.R. Agar, Gavin P. Dunn, Wenya Linda Bi, Sandro Santagata, Ian F. Dunn   +9 more
doaj   +1 more source